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| | asd | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (358 aa) |
| | dapA | 4-hydroxy-tetrahydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (293 aa) |
| | metC | Cystathionine gamma-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (379 aa) |
| | birA | Bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. (311 aa) |
| | galK_1 | LacI family transcriptional regulator; Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily. (392 aa) |
| | galT | Galactose-1-phosphate uridylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (493 aa) |
| | hom | Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (428 aa) |
| | thrB | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (288 aa) |
| | pyrK | Dihydroorotate dehydrogenase electron transfer subunit; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+). (268 aa) |
| | pyrDB | Dihydroorotate dehydrogenase B catalytic subunit; Catalyzes the conversion of dihydroorotate to orotate. (312 aa) |
| | pyrE | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (209 aa) |
| | ald | Alanine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the AlaDH/PNT family. (370 aa) |
| | coaE | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (197 aa) |
| | pyrC | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. (424 aa) |
| | metK | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (396 aa) |
| | murAB | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (419 aa) |
| | panE | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (315 aa) |
| | ligA | DNA ligase (NAD(+)) LigA; This protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. (319 aa) |
| | amyX_1 | Type I pullulanase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycosyl hydrolase 13 family. (766 aa) |
| | nrdD_1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (112 aa) |
| | guaA | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. (519 aa) |
| | glyA | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (418 aa) |
| | tdk | Thymidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (201 aa) |
| | xpt | Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. (193 aa) |
| | guaC | Guanosine monophosphate reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides; Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily. (327 aa) |
| | ldhA | L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (327 aa) |
| | ilvE | Branched chain amino acid aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (339 aa) |
| | plsY | Glycerol-3-phosphate acyltransferase; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. (215 aa) |
| | ribD | Deoxycytidylate deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. (155 aa) |
| | cobB | DNA-binding protein; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. (247 aa) |
| | eno | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (434 aa) |
| | A6J72_01025 | Hypothetical protein; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. (179 aa) |
| | AspB | Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (393 aa) |
| | cdd | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (129 aa) |
| | deoC1 | Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (220 aa) |
| | deoA | Pyrimidine-nucleoside phosphorylase; Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (425 aa) |
| | coaA | Type I pantothenate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (306 aa) |
| | Amy | Alpha-amylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (482 aa) |
| | glcK | Glucokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (319 aa) |
| | carB | Carbamoyl phosphate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CarB family. (1059 aa) |
| | carA | Carbamoyl phosphate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CarA family. (362 aa) |
| | pyrB | Aspartate carbamoyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (306 aa) |
| | pyrR | Bifunctional pyr operon transcriptional regulator/uracil phosphoribosyltransferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant; Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily. (173 aa) |
| | ndk | Nucleoside-diphosphate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (139 aa) |
| | ARC25972.1 | Acyl-[acyl-carrier-protein] thioesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (247 aa) |
| | dhfR | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (170 aa) |
| | thyA | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (279 aa) |
| | thiI | tRNA 4-thiouridine(8) synthase ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (404 aa) |
| | iscS_1 | Derived by automated computational analysis using gene prediction method: Protein Homology. (380 aa) |
| | fbp | Fructose-bisphosphatase class III; Class 3; catalyzes the formation of fructose 6-phosphate from fructose-1,6-bisphosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (640 aa) |
| | mgs | 1,2-diacylglycerol 3-glucosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (437 aa) |
| | dgs | Glycosyl transferase family 1; Derived by automated computational analysis using gene prediction method: Protein Homology. (332 aa) |
| | galE_1 | UDP-glucose 4-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (339 aa) |
| | rmlB | dTDP-glucose 4,6-dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (348 aa) |
| | rfbC | dTDP-4-dehydrorhamnose 3,5-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (197 aa) |
| | rmlA1 | Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. (289 aa) |
| | rmlD | dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. (283 aa) |
| | pheA | Prephenate dehydratase; Catalyzes the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (277 aa) |
| | aroK | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (158 aa) |
| | aroA | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (427 aa) |
| | TyrA | Prephenate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (368 aa) |
| | aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (388 aa) |
| | aroB | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (355 aa) |
| | aroE | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (284 aa) |
| | aroD | 3-dehydroquinase; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family. (225 aa) |
| | ltaS2 | Alkaline phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (724 aa) |
| | deoD_1 | Purine-nucleoside phosphorylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (236 aa) |
| | punA | Purine-nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (269 aa) |
| | rpiA | Ribose-5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (227 aa) |
| | tpiA_1 | Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (252 aa) |
| | ppc | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (899 aa) |
| | nrdE | Ribonucleotide-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (719 aa) |
| | plsC | 1-acyl-sn-glycerol-3-phosphate acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (246 aa) |
| | ARC26111.1 | beta-N-acetylhexosaminidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (627 aa) |
| | gldA | Glycerol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (362 aa) |
| | bssA | Formate C-acetyltransferase/glycerol dehydratase family glycyl radical enzyme; Derived by automated computational analysis using gene prediction method: Protein Homology. (814 aa) |
| | pgl | 6-phosphogluconolactonase; Derived by automated computational analysis using gene prediction method: Protein Homology. (337 aa) |
| | ARC26146.1 | MBL fold hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (211 aa) |
| | femX | UDP-N-acetylmuramoylpentapeptide-lysine N(6)-alanyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (404 aa) |
| | femA | Peptidoglycan branched peptide synthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (412 aa) |
| | nagB | Glucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. (235 aa) |
| | arcC1 | Carbamate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the carbamate kinase family. (315 aa) |
| | arcB | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (338 aa) |
| | arcA | Arginine deiminase; Derived by automated computational analysis using gene prediction method: Protein Homology. (409 aa) |
| | pyrH | UMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (246 aa) |
| | mtnN | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. (230 aa) |
| | nudF | ADP-ribose pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (183 aa) |
| | glmU | UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (459 aa) |
| | fabG_2 | NAD(P)-dependent dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (232 aa) |
| | metG | methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily. (665 aa) |
| | tmk | dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (212 aa) |
| | upp | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (209 aa) |
| | patB | Cysteine desulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology. (388 aa) |
| | murE | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of L-lysine to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan; Belongs to the MurCDEF family. MurE subfamily. (481 aa) |
| | treA | Alpha,alpha-phosphotrehalase; Derived by automated computational analysis using gene prediction method: Protein Homology. (547 aa) |
| | pckA | Phosphoenolpyruvate carboxykinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (548 aa) |
| | murG | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (356 aa) |
| | murD | UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (450 aa) |
| | coaD | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (165 aa) |
| | cysK | Cysteine synthase A; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cysteine synthase/cystathionine beta- synthase family. (309 aa) |
| | gmk | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (208 aa) |
| | luxS | S-ribosylhomocysteine lyase; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. (160 aa) |
| | ponA | Penicillin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (723 aa) |
| | nadE | NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. (274 aa) |
| | pncB2 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (486 aa) |
| | dacA_1 | D-alanyl-D-alanine carboxypeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S11 family. (413 aa) |
| | csd | Cysteine desulfurase; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. (410 aa) |
| | tagO | Undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (388 aa) |
| | fba | Fructose-1,6-bisphosphate aldolase, class II; Derived by automated computational analysis using gene prediction method: Protein Homology. (293 aa) |
| | mraY | Peptide ABC transporter ATP-binding protein; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (327 aa) |
| | nagA | N-acetylglucosamine-6-phosphate deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (383 aa) |
| | adhA | HAD family hydrolase; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. (340 aa) |
| | manX_1 | PTS mannose transporter subunit EIIAB; Derived by automated computational analysis using gene prediction method: Protein Homology. (329 aa) |
| | manY_1 | PTS mannose/fructose/sorbose transporter subunit IIC; Derived by automated computational analysis using gene prediction method: Protein Homology. (267 aa) |
| | manZ_1 | PTS mannose family transporter subunit IID; Hosphoenolpyruvate-dependent sugar phosphotransferase system catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IID with IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology. (303 aa) |
| | accA | Cytochrome O ubiquinol oxidase; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (256 aa) |
| | accD | acetyl-CoA carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (287 aa) |
| | accC | acetyl-CoA carboxylase biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (455 aa) |
| | fabZ | beta-hydroxyacyl-ACP dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (140 aa) |
| | accB | acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (159 aa) |
| | fabF | Beta-ketoacyl-[acyl-carrier-protein] synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (410 aa) |
| | fabG_1 | beta-ketoacyl-ACP reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (243 aa) |
| | FabK | [acyl-carrier-protein] S-malonyltransferase; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. (324 aa) |
| | fabH | 3-oxoacyl-ACP synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (324 aa) |
| | yclM | Aspartate kinase; Catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; lysine and threonine sensitive; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartokinase family. (449 aa) |
| | metE | 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (750 aa) |
| | hisK | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the PHP hydrolase family. HisK subfamily. (244 aa) |
| | ARC26455.1 | 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (381 aa) |
| | mtaD | Chlorohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (422 aa) |
| | pyrDA | Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate. (311 aa) |
| | gdhA | Glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (448 aa) |
| | pflB | Formate acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (771 aa) |
| | pksG | hydroxymethylglutaryl-CoA synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (390 aa) |
| | fni | Type 2 isopentenyl-diphosphate Delta-isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). (338 aa) |
| | ARC26494.1 | Phosphomevalonate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (332 aa) |
| | MvaD | Diphosphomevalonate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (314 aa) |
| | galK_2 | Mevalonate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (292 aa) |
| | gap | Type I glyceraldehyde-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (335 aa) |
| | thiN | Thiamine diphosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (210 aa) |
| | rpe | Ribulose-phosphate 3-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribulose-phosphate 3-epimerase family. (219 aa) |
| | glpK | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. (503 aa) |
| | pgi | Glucose-6-phosphate isomerase; Functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GPI family. (449 aa) |
| | purA | Restriction endonuclease; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (430 aa) |
| | thrC | Threonine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (494 aa) |
| | ntpD | V-type ATP synthase subunit D; Produces ATP from ADP in the presence of a proton gradient across the membrane. (207 aa) |
| | ntpB | V-type ATP synthase subunit B; Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit. (463 aa) |
| | ntpA | V-type ATP synthase subunit A; Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family. (596 aa) |
| | ntpG | V-type ATP synthase subunit F; Derived by automated computational analysis using gene prediction method: Protein Homology. (107 aa) |
| | ntpC | V-type ATP synthase subunit C; Derived by automated computational analysis using gene prediction method: Protein Homology. (336 aa) |
| | ntpK | V-type ATP synthase subunit K; Produces ATP from ADP in the presence of a proton gradient across the membrane; the K subunit is a nonenzymatic component which binds the dimeric form by interacting with the G and E subunits; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the V-ATPase proteolipid subunit family. (159 aa) |
| | NtpI | V-type ATP synthase subunit I; Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I is part of the membrane proton channel; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the V-ATPase 116 kDa subunit family. (652 aa) |
| | ARC26586.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (107 aa) |
| | murQ | N-acetylmuramic acid 6-phosphate etherase; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. (308 aa) |
| | nanA_1 | N-acetylneuraminate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (305 aa) |
| | nanE | N-acetylmannosamine-6-phosphate 2-epimerase; Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P). (234 aa) |
| | adhE | Bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. (883 aa) |
| | mro | Galactose mutarotase; Converts alpha-aldose to the beta-anomer. (348 aa) |
| | lacD | Tagatose-bisphosphate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldolase LacD family. (333 aa) |
| | manX_5 | PTS fructose transporter subunit IIA; Derived by automated computational analysis using gene prediction method: Protein Homology. (134 aa) |
| | manZ_4 | PTS fructose transporter subunit IID; Derived by automated computational analysis using gene prediction method: Protein Homology. (275 aa) |
| | agaC_2 | PTS fructose transporter subunit IIC; Derived by automated computational analysis using gene prediction method: Protein Homology. (297 aa) |
| | purB | Adenylosuccinate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (431 aa) |
| | purH | Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (516 aa) |
| | purN | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (184 aa) |
| | purM | Phosphoribosylformylglycinamidine cyclo-ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (339 aa) |
| | purF | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (479 aa) |
| | purL | Phosphomethylpyrimidine kinase; Internal stop; Derived by automated computational analysis using gene prediction method: Protein Homology. (1241 aa) |
| | purC | Phosphoribosylaminoimidazolesuccinocarboxamide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SAICAR synthetase family. (235 aa) |
| | plsX | Phosphate acyltransferase; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (332 aa) |
| | patA_2 | Catalyzes the transamination of the aromatic amino acid forming a ketoacid; first step in aromatic amino acid degradation in lactococci; Derived by automated computational analysis using gene prediction method: Protein Homology. (395 aa) |
| | prs | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (322 aa) |
| | tpiA_2 | Triose-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (229 aa) |
| | galE_2 | UDP-glucose 4-epimerase GalE; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (332 aa) |
| | guaB | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (493 aa) |
| | A6J72_05550 | Peptidoglycan-binding protein; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. (214 aa) |
| | sdhA | L-serine ammonia-lyase, iron-sulfur-dependent, subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the iron-sulfur dependent L-serine dehydratase family. (290 aa) |
| | sdhB | L-serine dehydratase, iron-sulfur-dependent subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the iron-sulfur dependent L-serine dehydratase family. (223 aa) |
| | dltA | D-alanine--poly(phosphoribitol) ligase; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Belongs to the ATP-de [...] (516 aa) |
| | amyX_2 | Type I pullulanase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycosyl hydrolase 13 family. (691 aa) |
| | malQ | Hypothetical protein; Internal stop; Derived by automated computational analysis using gene prediction method: Protein Homology. (503 aa) |
| | malP | Maltose phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (753 aa) |
| | cls | Cardiolipin synthase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol; Belongs to the phospholipase D family. Cardiolipin synthase subfamily. (510 aa) |
| | nrdD_1-2 | Anaerobic ribonucleoside-triphosphate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (736 aa) |
| | glcB | PTS mannose transporter subunit IIAB; Derived by automated computational analysis using gene prediction method: Protein Homology. (564 aa) |
| | A6J72_06165 | Hypothetical protein; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. (180 aa) |
| | adk | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (212 aa) |
| | gtaB | UTP--glucose-1-phosphate uridylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (299 aa) |
| | dut | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. (147 aa) |
| | gltX | glutamate--tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (487 aa) |
| | HipO | 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase; Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate. (376 aa) |
| | ARC26858.1 | 5-formyltetrahydrofolate cyclo-ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (175 aa) |
| | pbpF_2 | Transglycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (780 aa) |
| | pgk | Phosphoglycerate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phosphoglycerate kinase family. (398 aa) |
| | glnA | Type I glutamate--ammonia ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family. (448 aa) |
| | ackA | SAM-dependent methyltransferase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (399 aa) |
| | glmS | Glutamine--fructose-6-phosphate transaminase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (604 aa) |
| | ulaA | ATP-dependent Clp protease ATP-binding subunit; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. (486 aa) |
| | ulaC | PTS ascorbate transporter subunit IIA; Phosphoenolpyruvate-dependent sugar phosphotransferase system; functions with enzymes IIB (sgaB; ulaB) and IIC (sgaT; ulaA) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology. (161 aa) |
| | ulaD | Catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate in anaerobic L-ascorbate utilization; Derived by automated computational analysis using gene prediction method: Protein Homology. (221 aa) |
| | ulaE | Xylulose 5-phosphate 3-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (287 aa) |
| | ulaG | L-ascorbate-6-phosphate lactonase; Derived by automated computational analysis using gene prediction method: Protein Homology. (363 aa) |
| | tkt | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (658 aa) |
| | cdsA | Phosphatidate cytidylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CDS family. (267 aa) |
| | fgs_2 | Dihydrofolate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the folylpolyglutamate synthase family. (441 aa) |
| | manX_2 | PTS fructose transporter subunit IIA; Derived by automated computational analysis using gene prediction method: Protein Homology. (145 aa) |
| | manY_2 | PTS sorbose transporter subunit IIC; Derived by automated computational analysis using gene prediction method: Protein Homology. (282 aa) |
| | relA | GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (738 aa) |
| | cysE | Serine O-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (194 aa) |
| | BasA | Glutathione peroxidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutathione peroxidase family. (158 aa) |
| | kdgA | Bifunctional 2-keto-4-hydroxyglutarate aldolase/2-keto-3-deoxy-6-phosphogluconate aldolase; Catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (209 aa) |
| | kdgK | 2-keto-3-deoxygluconate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (333 aa) |
| | manX_4 | PTS N-acetylgalactosamine transporter subunit IIA; Derived by automated computational analysis using gene prediction method: Protein Homology. (144 aa) |
| | sorB | PTS N-acetylgalactosamine transporter subunit IIB; Derived by automated computational analysis using gene prediction method: Protein Homology. (163 aa) |
| | agaC_1 | PTS N-acetylgalactosamine transporter subunit IIC; Catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake;involved in N-acetylgalactosamine transport; Derived by automated computational analysis using gene prediction method: Protein Homology. (259 aa) |
| | manZ_3 | PTS N-acetylgalactosamine transporter subunit IID; Catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IID with IIC forms the translocation channel for the sugar uptake; involved in N-acetylgalactosamine transport; Derived by automated computational analysis using gene prediction method: Protein Homology. (271 aa) |
| | pdxK | Phosphomethylpyrimidine kinase; Catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine; Derived by automated computational analysis using gene prediction method: Protein Homology. (257 aa) |
| | pyrG_2 | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (536 aa) |
| | scrB | Sucrose-6-phosphate hydrolase; Enables the bacterium to metabolize sucrose as a sole carbon source; Belongs to the glycosyl hydrolase 32 family. (484 aa) |
| | gmuE | Fructokinase/branched chain amino acid--2-keto-4-methylthiobutyrate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (299 aa) |
| | gmuF | GntR family transcriptional regulator; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the mannose-6-phosphate isomerase type 1 family. (314 aa) |
| | aroG | 3-deoxy-7-phosphoheptulonate synthase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (346 aa) |
| | alr | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (368 aa) |
| | ansB | L-asparaginase; Derived by automated computational analysis using gene prediction method: Protein Homology. (320 aa) |
| | alaA | Aminotransferase; Broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; Derived by automated computational analysis using gene prediction method: Protein Homology. (404 aa) |
| | gatC_2 | aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family. (100 aa) |
| | gatA | aspartyl/glutamyl-tRNA amidotransferase subunit A; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). (488 aa) |
| | gatB | aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily. (477 aa) |
| | nadD | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (212 aa) |
| | dapE | Peptidase M20; Derived by automated computational analysis using gene prediction method: Protein Homology. (457 aa) |
| | gnd | Phosphogluconate dehydrogenase (NADP(+)-dependent, decarboxylating); Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (474 aa) |
| | crr | PTS sugar transporter subunit IIA; Derived by automated computational analysis using gene prediction method: Protein Homology. (189 aa) |
| | mapP | Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (271 aa) |
| | murC | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (443 aa) |
| | lysA | Hypothetical protein; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. (416 aa) |
| | murI | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. (264 aa) |
| | rdgB | Non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (328 aa) |
| | folD | Bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (284 aa) |
| | IspA | Geranyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FPP/GGPP synthase family. (300 aa) |
| | gpmA_2 | Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (230 aa) |
| | penA | Penicillin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (682 aa) |
| | ddl | D-alanine--D-alanine ligase A; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (348 aa) |
| | murF | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (456 aa) |
| | lacD2 | Tagatose-bisphosphate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldolase LacD family. (315 aa) |
| | lacB | Galactose-6-phosphate isomerase; Catalyzes the interconversion of galactose 6-phosphate to tagatose 6-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (172 aa) |
| | lacA | Galactose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (143 aa) |
| | lacC_2 | Phosphofructokinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the carbohydrate kinase PfkB family. LacC subfamily. (310 aa) |
| | strH | Glycoside hydrolase family 2; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycosyl hydrolase 2 family. (2222 aa) |
| | lacF_1 | PTS lactose transporter subunit IIA; Catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; Derived by automated computational analysis using gene prediction method: Protein Homology. (106 aa) |
| | lacE_2 | PTS lactose transporter subunit IIBC; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology. (567 aa) |
| | lacG | 6-phospho-beta-galactosidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycosyl hydrolase 1 family. (468 aa) |
| | nrnA_1 | DHH family phosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (312 aa) |
| | alsS | Acetolactate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. (554 aa) |
| | GlgB | 1,4-alpha-glucan branching enzyme; Derived by automated computational analysis using gene prediction method: Protein Homology. (636 aa) |
| | glgC | Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (380 aa) |
| | glgD | Glucose-1-phosphate adenylyltransferase subunit GlgD; Derived by automated computational analysis using gene prediction method: Protein Homology. (379 aa) |
| | glgA | Starch synthase; Synthesizes alpha-1,4-glucan chains using ADP-glucose. (477 aa) |
| | glgP | Glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (799 aa) |
| | atpB | F0F1 ATP synthase subunit A; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family. (237 aa) |
| | atpF | ATP synthase F0 subunit B; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (164 aa) |
| | atpH | F0F1 ATP synthase subunit delta; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (178 aa) |
| | atpA | F0F1 ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. (501 aa) |
| | atpG | F0F1 ATP synthase subunit gamma; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (292 aa) |
| | atpD | ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. (468 aa) |
| | atpC | F0F1 ATP synthase subunit epsilon; Produces ATP from ADP in the presence of a proton gradient across the membrane. (139 aa) |
| | murAA | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (426 aa) |
| | apt | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (170 aa) |
| | pgcA_2 | Phosphoglucomutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (563 aa) |
| | pepN | Aminopeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (847 aa) |
| | lacC_1 | DeoR family transcriptional regulator; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the carbohydrate kinase PfkB family. LacC subfamily. (297 aa) |
| | fruA_2 | PTS fructose transporter subunit IIC; Derived by automated computational analysis using gene prediction method: Protein Homology. (649 aa) |
| | dapB | EDD domain protein; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (255 aa) |
| | gor | Glutathione-disulfide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (449 aa) |
| | miaA | tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (294 aa) |
| | pfkA | ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (336 aa) |
| | pyk | Pyruvate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pyruvate kinase family. (500 aa) |
| | ribF | Riboflavin biosynthesis protein RibF; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribF family. (310 aa) |
| | suhB | Inositol monophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (303 aa) |
| | iscS_2 | Cysteine desulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology. (371 aa) |
| | prs2 | Ribose-phosphate diphosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (323 aa) |
| | yjbM | GTP pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (223 aa) |
| | ppnK | NAD(+) kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (272 aa) |
| | pta | Phosphate acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (325 aa) |
| | pgcA_1 | Phosphoglucomutase; Catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (572 aa) |
| | coaBC_2 | Phosphopantothenoylcysteine decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (183 aa) |
| | fhs1 | Formate--tetrahydrofolate ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the formate--tetrahydrofolate ligase family. (556 aa) |
| | zwf | Spore gernimation protein GerA; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (495 aa) |
| | cobQ | Glutamine amidotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (261 aa) |
| | ARC27379.1 | UDP-N-acetylmuramyl peptide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (447 aa) |
| | glmM | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. (450 aa) |
| | serB | Phosphoserine phosphatase SerB; Derived by automated computational analysis using gene prediction method: Protein Homology. (216 aa) |
| | glxK | Glycerate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycerate kinase type-1 family. (370 aa) |
| | gloA | Lactoylglutathione lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (128 aa) |
| | udk | Uridine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (211 aa) |
| | hemH | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (365 aa) |
| | murB | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (300 aa) |
