STRINGSTRING
BD94_0095 BD94_0095 ftsH ftsH groL groL groS groS BD94_0587 BD94_0587 BD94_0757 BD94_0757 dnaK dnaK BD94_0827 BD94_0827 BD94_1022 BD94_1022 alaS alaS BD94_1161 BD94_1161 clpP clpP BD94_1697 BD94_1697 BD94_1856 BD94_1856 BD94_1857 BD94_1857 BD94_2085 BD94_2085 BD94_2094 BD94_2094 BD94_2364 BD94_2364 BD94_2398 BD94_2398 BD94_2496 BD94_2496 BD94_2512 BD94_2512 BD94_2612 BD94_2612 BD94_2646 BD94_2646 grpE grpE dnaJ dnaJ BD94_2777 BD94_2777 BD94_3424 BD94_3424 clpB clpB BD94_3681 BD94_3681 BD94_3692 BD94_3692 BD94_3849 BD94_3849 lon lon
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BD94_0095ClpB protein; Belongs to the ClpA/ClpB family. (845 aa)
ftsHCell division protein FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (657 aa)
groLHeat shock protein 60 family chaperone GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. (541 aa)
groSHeat shock protein 60 family co-chaperone GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. (92 aa)
BD94_0587Chaperone protein HtpG. (631 aa)
BD94_0757Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit; S4 paralog. (149 aa)
dnaKChaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. (628 aa)
BD94_0827Hypothetical protein; Belongs to the ClpS family. (102 aa)
BD94_1022Membrane protein. (349 aa)
alaSAlanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (867 aa)
BD94_1161Cell division protein FtsH. (447 aa)
clpPATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. (227 aa)
BD94_1697ClpB protein; Belongs to the ClpA/ClpB family. (830 aa)
BD94_1856Hypothetical protein. (129 aa)
BD94_1857Hypothetical protein. (181 aa)
BD94_2085Membrane protein. (275 aa)
BD94_2094Hypothetical protein. (822 aa)
BD94_2364Cell division protein FtsH. (240 aa)
BD94_2398Hypothetical protein. (455 aa)
BD94_2496Peptidyl-prolyl cis-trans isomerase. (340 aa)
BD94_2512Hypothetical protein. (272 aa)
BD94_2612FKBP-type peptidyl-prolyl cis-trans isomerase fklB. (144 aa)
BD94_2646Membrane protein containing heat shock protein DnaJ N-terminal domain. (188 aa)
grpEHeat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...] (178 aa)
dnaJChaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] (370 aa)
BD94_2777Hypothetical protein. (325 aa)
BD94_3424ATP-dependent Clp protease ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. (396 aa)
clpBClpB protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. (864 aa)
BD94_3681Non-specific DNA-binding protein Dps/Iron-binding ferritin-like antioxidant protein/Ferroxidase; Belongs to the Dps family. (158 aa)
BD94_3692HtrA protease/chaperone protein. (500 aa)
BD94_3849Small heat shock protein; Belongs to the small heat shock protein (HSP20) family. (155 aa)
lonATP-dependent protease La Type I; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. (799 aa)
Your Current Organism:
Elizabethkingia anophelis
NCBI taxonomy Id: 1338011
Other names: E. anophelis NUHP1, Elizabethkingia anophelis NUHP1
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