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| | rnz | Ribonuclease Z; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family. (304 aa) |
| | rsmI | rRNA small subunit methyltransferase I; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. (224 aa) |
| | BD94_0030 | RNA polymerase ECF-type sigma factor. (106 aa) |
| | BD94_0048 | tRNA-(ms[2]io[6]A)-hydroxylase. (192 aa) |
| | BD94_0053 | RNA polymerase ECF-type sigma factor; Belongs to the sigma-70 factor family. ECF subfamily. (177 aa) |
| | rplU | LSU ribosomal protein L21p; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. (132 aa) |
| | rpmA | LSU ribosomal protein L27p; Belongs to the bacterial ribosomal protein bL27 family. (85 aa) |
| | rsmH | rRNA small subunit methyltransferase H; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. (297 aa) |
| | BD94_0147 | TRNA/rRNA methyltransferase. (176 aa) |
| | BD94_0158 | Hypothetical protein. (440 aa) |
| | tgt | tRNA-guanine transglycosylase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the [...] (378 aa) |
| | rho | Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (577 aa) |
| | BD94_0187 | RNA polymerase sigma-70 factor, ECF subfamily. (196 aa) |
| | BD94_0195 | Tryptophanyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (321 aa) |
| | BD94_0199 | Outer membrane protein H precursor. (166 aa) |
| | ileS | Isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1128 aa) |
| | BD94_0220 | RNA polymerase ECF-type sigma factor; Belongs to the sigma-70 factor family. ECF subfamily. (169 aa) |
| | rpmE2 | LSU ribosomal protein L31p. (84 aa) |
| | trmB | tRNA (guanine46-N7-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. (224 aa) |
| | rplM | LSU ribosomal protein L13p (L13Ae); This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (151 aa) |
| | rpsI | SSU ribosomal protein S9p (S16e); Belongs to the universal ribosomal protein uS9 family. (128 aa) |
| | rpsB | SSU ribosomal protein S2p (SAe); Belongs to the universal ribosomal protein uS2 family. (252 aa) |
| | tsf | Translation elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family. (274 aa) |
| | gltX | Glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (503 aa) |
| | rpmF | LSU ribosomal protein L32p; Belongs to the bacterial ribosomal protein bL32 family. (67 aa) |
| | BD94_0275 | Putative O-methyltransferase; Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC). (229 aa) |
| | rpmH | LSU ribosomal protein L34p; Belongs to the bacterial ribosomal protein bL34 family. (51 aa) |
| | tilS | tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (433 aa) |
| | leuS | Leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (939 aa) |
| | BD94_0304 | Transcription termination protein NusB. (301 aa) |
| | aspS | Aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (584 aa) |
| | BD94_0320 | RNA methyltransferase, TrmA family; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (470 aa) |
| | rnc | Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. (256 aa) |
| | cysS | Cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (487 aa) |
| | rpsU | SSU ribosomal protein S21p; Belongs to the bacterial ribosomal protein bS21 family. (65 aa) |
| | BD94_0359 | Translation elongation factor Tu. (368 aa) |
| | nusG | Transcription antitermination protein NusG; Participates in transcription elongation, termination and antitermination. (180 aa) |
| | rplK | LSU ribosomal protein L11p (L12e); Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. (147 aa) |
| | rplA | LSU ribosomal protein L1p (L10Ae); Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. (230 aa) |
| | rplJ | LSU ribosomal protein L10p (P0); Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (196 aa) |
| | rplL | LSU ribosomal protein L7/L12 (P1/P2); Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family. (122 aa) |
| | BD94_0371 | Protein YicC. (285 aa) |
| | miaA | tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (311 aa) |
| | rpmB | LSU ribosomal protein L28p; Belongs to the bacterial ribosomal protein bL28 family. (78 aa) |
| | BD94_0402 | LSU ribosomal protein L33p / LSU ribosomal protein L33p, zinc-independent. (39 aa) |
| | BD94_0407 | Hypothetical protein. (577 aa) |
| | fmt | Methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. (315 aa) |
| | BD94_0422 | RNA polymerase ECF-type sigma factor; Belongs to the sigma-70 factor family. ECF subfamily. (179 aa) |
| | BD94_0436 | RNA polymerase ECF-type sigma factor; Belongs to the sigma-70 factor family. ECF subfamily. (164 aa) |
| | BD94_0480 | Hypothetical protein. (401 aa) |
| | argS | Arginyl-tRNA synthetase. (587 aa) |
| | BD94_0575 | Hypothetical protein YaeJ with similarity to translation release factor. (130 aa) |
| | BD94_0576 | Deoxyhypusine synthase. (325 aa) |
| | trmD | tRNA (Guanine37-N1) -methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. (200 aa) |
| | rimO | Ribosomal protein S12p Asp88 methylthiotransferase; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily. (434 aa) |
| | BD94_0761 | tRNA dihydrouridine synthase B; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. (329 aa) |
| | BD94_0781 | RNA polymerase ECF-type sigma factor; Belongs to the sigma-70 factor family. ECF subfamily. (185 aa) |
| | BD94_0787 | Putative Holliday junction resolvase; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. (136 aa) |
| | def | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. (190 aa) |
| | BD94_0830 | tRNA/rRNA methyltransferase. (242 aa) |
| | frr | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. (184 aa) |
| | BD94_0870 | Sigma factor; Belongs to the sigma-70 factor family. ECF subfamily. (184 aa) |
| | BD94_0913 | Hypothetical protein. (110 aa) |
| | BD94_0929 | Protein RtcB. (460 aa) |
| | BD94_0951 | Hypothetical protein. (110 aa) |
| | BD94_0991 | RNA polymerase ECF-type sigma factor; Belongs to the sigma-70 factor family. ECF subfamily. (166 aa) |
| | BD94_1015 | CAAX amino terminal protease family. (302 aa) |
| | mnmE | GTPase and tRNA-U34 5-formylation enzyme TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. (461 aa) |
| | pheS | Phenylalanyl-tRNA synthetase alpha chain; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. (336 aa) |
| | BD94_1109 | Hypothetical protein. (229 aa) |
| | BD94_1149 | Hypothetical protein. (245 aa) |
| | alaS | Alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (867 aa) |
| | prfB | Peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. (369 aa) |
| | BD94_1193 | MiaB family protein, possibly involved in tRNA or rRNA modification. (448 aa) |
| | BD94_1211 | L-asparaginase. (331 aa) |
| | BD94_1225 | tRNA nucleotidyltransferase; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. (474 aa) |
| | BD94_1226 | Sua5 YciO YrdC YwlC family protein; Belongs to the SUA5 family. (182 aa) |
| | tyrS | Tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. (431 aa) |
| | BD94_1250 | RNA polymerase sigma-70 factor; Belongs to the sigma-70 factor family. ECF subfamily. (186 aa) |
| | lipA | Lipoate synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (290 aa) |
| | BD94_1281 | Cytoplasmic axial filament protein CafA and Ribonuclease G. (518 aa) |
| | queG | Iron-sulfur cluster-binding protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family. (311 aa) |
| | BD94_1309 | Protein secretion chaperonin CsaA. (114 aa) |
| | pheT | Phenylalanyl-tRNA synthetase beta chain; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. (799 aa) |
| | BD94_1442 | Signal peptidase I; Belongs to the peptidase S26 family. (534 aa) |
| | BD94_1594 | TonB-dependent receptor. (1049 aa) |
| | BD94_1832 | RNA-binding protein. (86 aa) |
| | def-2 | Peptide deformylase 8; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. (193 aa) |
| | BD94_1981 | SusC, outer membrane protein involved in starch binding. (921 aa) |
| | BD94_2028 | Ribosomal large subunit pseudouridine synthase B; Belongs to the pseudouridine synthase RsuA family. (328 aa) |
| | def-3 | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. Belongs to the polypeptide deformylase family. (205 aa) |
| | BD94_2045 | Putative peptidase. (224 aa) |
| | BD94_2051 | Sua5 YciO YrdC YwlC family protein; Belongs to the SUA5 family. (205 aa) |
| | rlmH | LSU m3Psi1915 methyltransferase RlmH; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. (157 aa) |
| | BD94_2192 | RNA polymerase ECF-type sigma factor; Belongs to the sigma-70 factor family. ECF subfamily. (138 aa) |
| | BD94_2200 | Tetrapyrrole (Corrin-Porphyrin) methylase family protein. (232 aa) |
| | prfC | Peptide chain release factor; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily. (532 aa) |
| | BD94_2206 | CAAX amino terminal protease family protein. (276 aa) |
| | rsmA | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. (255 aa) |
| | truB | tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. (235 aa) |
| | BD94_2243 | SAM-dependent methyltransferase. (384 aa) |
| | BD94_2253 | Isoaspartyl aminopeptidase / Asp-X dipeptidase. (334 aa) |
| | BD94_2266 | RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (288 aa) |
| | rsmG | rRNA small subunit methyltransferase, glucose inhibited division protein GidB; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family. (209 aa) |
| | BD94_2323 | RNA polymerase ECF-type sigma factor; Belongs to the sigma-70 factor family. ECF subfamily. (266 aa) |
| | lysS | Lysyl-tRNA synthetase (class II); Belongs to the class-II aminoacyl-tRNA synthetase family. (567 aa) |
| | BD94_2387 | Translation initiation factor SUI1-related protein. (107 aa) |
| | rlmN | Ribosomal RNA large subunit methyltransferase N; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family. (347 aa) |
| | metG | Methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (677 aa) |
| | lipB | Octanoate-[acyl-carrier-protein]-protein-N- octanoyltransferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. (237 aa) |
| | rpsF | SSU ribosomal protein S6p; Binds together with S18 to 16S ribosomal RNA. (135 aa) |
| | rpsR | SSU ribosomal protein S18p / SSU ribosomal protein S18p, zinc-independent; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. (100 aa) |
| | rplI | LSU ribosomal protein L9p; Binds to the 23S rRNA. (166 aa) |
| | BD94_2501 | TonB-dependent receptor. (965 aa) |
| | BD94_2513 | Hypothetical protein. (118 aa) |
| | hisS | Histidyl-tRNA synthetase. (449 aa) |
| | rplS | LSU ribosomal protein L19p; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. (118 aa) |
| | BD94_2556 | SSU ribosomal protein S1p; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. (594 aa) |
| | thrS | Threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). (643 aa) |
| | infC | Translation initiation factor 3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins. (174 aa) |
| | rpmI | LSU ribosomal protein L35p; Belongs to the bacterial ribosomal protein bL35 family. (65 aa) |
| | BD94_2579 | LSU ribosomal protein L20p; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. (97 aa) |
| | BD94_2594 | RNA-binding protein. (93 aa) |
| | BD94_2732 | Methyltransferase; Belongs to the methyltransferase superfamily. (394 aa) |
| | proS | Prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). (491 aa) |
| | BD94_2779 | RNA polymerase sigma-70 factor; Belongs to the sigma-70 factor family. ECF subfamily. (158 aa) |
| | BD94_2847 | Isoaspartyl aminopeptidase / Asp-X dipeptidase. (333 aa) |
| | efp | Translation elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. (187 aa) |
| | BD94_2860 | ATPase YjeE, predicted to have essential role in cell wall biosynthesis. (136 aa) |
| | pnp | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. (729 aa) |
| | rpsO | SSU ribosomal protein S15p (S13e); Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome. (89 aa) |
| | rbfA | Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. (119 aa) |
| | BD94_3017 | Phenylalanyl-tRNA synthetase alpha chain; Belongs to the class-II aminoacyl-tRNA synthetase family. (344 aa) |
| | BD94_3056 | Glutaminyl-tRNA synthetase. (556 aa) |
| | BD94_3078 | Ribosomal large subunit pseudouridine synthase F; Belongs to the pseudouridine synthase RsuA family. (240 aa) |
| | BD94_3128 | 23S rRNA (guanosine-2'-O-) -methyltransferase rlmB; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. (252 aa) |
| | tsaD | YgjD/Kae1/Qri7 family, required for threonylcarbamoyladenosine (t(6)A) formation in tRNA; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. (338 aa) |
| | BD94_3154 | Ribosomal RNA small subunit methyltransferase E; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. (231 aa) |
| | trmH | tRNA (Guanosine18-2'-O-) -methyltransferase; Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. (215 aa) |
| | BD94_3347 | TonB-dependent receptor. (940 aa) |
| | valS | Valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (871 aa) |
| | BD94_3358 | RNA polymerase ECF-type sigma factor; Belongs to the sigma-70 factor family. ECF subfamily. (164 aa) |
| | BD94_3360 | RNA polymerase sigma-54 factor RpoN. (487 aa) |
| | asnS | Asparaginyl-tRNA synthetase. (482 aa) |
| | rimM | 16S rRNA processing protein RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family. (180 aa) |
| | rpsP | SSU ribosomal protein S16p; Belongs to the bacterial ribosomal protein bS16 family. (190 aa) |
| | truA | tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (257 aa) |
| | BD94_3377 | Ribosomal RNA small subunit methyltransferase D. (186 aa) |
| | BD94_3385 | Ribosomal large subunit pseudouridine synthase D 0; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (353 aa) |
| | rpoB | DNA-directed RNA polymerase beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1274 aa) |
| | rpoC | DNA-directed RNA polymerase beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1420 aa) |
| | smpB | tmRNA-binding protein SmpB; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switc [...] (152 aa) |
| | BD94_3634 | LSU ribosomal protein L17p; Belongs to the bacterial ribosomal protein bL17 family. (151 aa) |
| | rpoA | DNA-directed RNA polymerase alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (331 aa) |
| | rpsD | SSU ribosomal protein S4p (S9e); One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (201 aa) |
| | rpsK | SSU ribosomal protein S11p (S14e); Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. (129 aa) |
| | rpsM | SSU ribosomal protein S13p (S18e); Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family. (125 aa) |
| | infA | Translation initiation factor 1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. (71 aa) |
| | rplO | LSU ribosomal protein L15p (L27Ae); Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (149 aa) |
| | rpmD | LSU ribosomal protein L30p (L7e). (59 aa) |
| | rpsE | SSU ribosomal protein S5p (S2e); Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family. (173 aa) |
| | rplR | LSU ribosomal protein L18p (L5e); This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (118 aa) |
| | rplF | LSU ribosomal protein L6p (L9e); This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (181 aa) |
| | rpsH | SSU ribosomal protein S8p (S15Ae); One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (132 aa) |
| | rpsN | SSU ribosomal protein S14p (S29e); Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family. (89 aa) |
| | rplE | LSU ribosomal protein L5p (L11e); This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (183 aa) |
| | rplX | LSU ribosomal protein L24p (L26e); One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit. (106 aa) |
| | rplN | LSU ribosomal protein L14p (L23e); Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (122 aa) |
| | rpsQ | SSU ribosomal protein S17p (S11e); One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (84 aa) |
| | rpmC | LSU ribosomal protein L29p (L35e); Belongs to the universal ribosomal protein uL29 family. (61 aa) |
| | rplP | LSU ribosomal protein L16p (L10e); Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. (141 aa) |
| | rpsC | SSU ribosomal protein S3p (S3e); Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. (242 aa) |
| | rplV | LSU ribosomal protein L22p (L17e); The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome. (134 aa) |
| | rpsS | SSU ribosomal protein S19p (S15e); Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (92 aa) |
| | rplB | LSU ribosomal protein L2p (L8e); One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (273 aa) |
| | rplW | LSU ribosomal protein L23p (L23Ae); One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family. (96 aa) |
| | rplD | LSU ribosomal protein L4p (L1e); Forms part of the polypeptide exit tunnel. (209 aa) |
| | rplC | LSU ribosomal protein L3p (L3e); One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. (208 aa) |
| | rpsJ | SSU ribosomal protein S10p (S20e); Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (101 aa) |
| | fusA | Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...] (705 aa) |
| | rpsG | SSU ribosomal protein S7p (S5e); One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. (158 aa) |
| | rpsL | SSU ribosomal protein S12p (S23e); Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit. (135 aa) |
| | BD94_3687 | Putative rRNA methylase. (254 aa) |
| | BD94_3691 | Rhodanese-related sulfurtransferase; Belongs to the UPF0176 family. (454 aa) |
| | BD94_3781 | TonB-dependent receptor. (534 aa) |
| | BD94_3784 | TonB-dependent receptor. (980 aa) |
| | infB | Translation initiation factor 2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. (955 aa) |
| | nusA | Transcription termination protein NusA; Participates in both transcription termination and antitermination. (415 aa) |
| | pth | Peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. (187 aa) |
| | BD94_3853 | RNA polymerase sigma-54 factor RpoN; Belongs to the sigma-70 factor family. ECF subfamily. (183 aa) |
| | BD94_3869 | RNA pseudouridylate synthase, group 1. (226 aa) |
| | BD94_3880 | Seryl-tRNA synthetase. (421 aa) |
| | BD94_3901 | Peptide chain release factor-like protein. (232 aa) |
| | BD94_3903 | RNA-2',3'-PO4:RNA-5'-OH ligase. (463 aa) |
| | prfA | Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. (361 aa) |
| | BD94_3919 | Hypothetical protein; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (107 aa) |
| | BD94_3926 | HesA/MoeB/ThiF family protein. (244 aa) |
| | rnpA | Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. (116 aa) |
| | miaB | tRNA-i(6)A37 methylthiotransferase; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. (478 aa) |
| | rplY | LSU ribosomal protein L25p; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily. (203 aa) |
| | glyQS | Glycyl-tRNA synthetase; Catalyzes the attachment of glycine to tRNA(Gly). Belongs to the class-II aminoacyl-tRNA synthetase family. (513 aa) |
| | BD94_3971 | Late embryogenesis abundant protein precursor. (137 aa) |
| | tadA | tRNA-specific adenosine-34 deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. (143 aa) |
| | mnmA | tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (394 aa) |
| | kptA | RNA:NAD 2'-phosphotransferase; Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''- cyclic phosphate (APPR>P). May function as an ADP-ribosylase. (180 aa) |
| | lepA | Translation elongation factor LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. (598 aa) |
| | BD94_4057 | RNA polymerase ECF-type sigma factor; Belongs to the sigma-70 factor family. ECF subfamily. (185 aa) |
| | BD94_4063 | Inactive metal-dependent proteasesilike protein, putative molecular chaperone. (225 aa) |
| | mnmG | tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. (620 aa) |
| | ybeY | Metal-dependent hydrolase; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. (135 aa) |
