97 items (Rhizopus microsporus) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	A0A2G4SKW5	NAD(P)H-hydrate epimerase; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX. (230 aa)
	A0A2G4SLC1	FSH1-domain-containing protein. (235 aa)
	A0A2G4SLP6	Dihydrofolate synthetase; Belongs to the folylpolyglutamate synthase family. (417 aa)
	UBA4	Adenylyltransferase and sulfurtransferase UBA4; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Acts by mediating the C-terminal thiocarboxylation of sulfur carrier URM1. Its N-terminus first activates URM1 as acyl-adenylate (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 to form thiocarboxylation (-COSH) of its C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards URM1. Subseque [...] (452 aa)
	A0A2G4SMB8	Uncharacterized protein. (442 aa)
	A0A2G4SMD2	Propionyl-CoA carboxylase. (552 aa)
	A0A2G4SME8	4'-phosphopantetheinyl transferase. (255 aa)
	A0A2G4SMG5	Uncharacterized protein. (707 aa)
	A0A2G4SNH2	Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family. (710 aa)
	A0A2G4SNK2	Riboflavin synthase domain-like protein. (708 aa)
	A0A2G4SNT0	Riboflavin kinase. (169 aa)
	A0A2G4SP51	Solute carrier family 25 protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (306 aa)
	A0A2G4SP60	Class II aaRS and biotin synthetase. (667 aa)
	A0A2G4SPE5	Uncharacterized protein. (496 aa)
	A0A2G4SPK6	Mitochondrial carrier; Belongs to the mitochondrial carrier (TC 2.A.29) family. (319 aa)
	A0A2G4SQE5	ATP-dependent (S)-NAD(P)H-hydrate dehydratase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Belongs to the NnrD/CARKD family. (319 aa)
	A0A2G4SQS7	Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1243 aa)
	A0A2G4SQU3	Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released. (625 aa)
	A0A2G4ST56	Uncharacterized protein. (192 aa)
	A0A2G4STQ9	Carboxyl transferase. (514 aa)
	A0A2G4STT2	Rhodanese domain-containing protein. (313 aa)
	A0A2G4STX5	Uncharacterized protein. (317 aa)
	A0A2G4SU89	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (608 aa)
	A0A2G4SUL7	ATP-NAD kinase. (376 aa)
	A0A2G4SUT2	FTHFS-domain-containing protein. (937 aa)
	A0A2G4SUW9	Cytochrome b5; Belongs to the cytochrome b5 family. (131 aa)
	A0A2G4SVU0	General substrate transporter; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (505 aa)
	A0A2G4SW30	Phosphodiest-domain-containing protein. (419 aa)
	A0A2G4SWJ6	Xanthine/uracil permease. (606 aa)
	A0A2G4SWV2	Pyridoxal kinase. (333 aa)
	A0A2G4SWZ0	A1pp-domain-containing protein. (182 aa)
	A0A2G4SX43	Cysteine desulfurylase. (459 aa)
	A0A2G4SXS1	Carboxyl transferase. (502 aa)
	A0A2G4SXX0	Uncharacterized protein. (545 aa)
	A0A2G4SY10	Xanthine/uracil permease. (483 aa)
	A0A2G4SY23	Cytochrome b5; Belongs to the cytochrome b5 family. (123 aa)
	A0A2G4SY91	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family. (199 aa)
	A0A2G4SYH5	Nudix hydrolase domain-containing protein. (307 aa)
	A0A2G4SZ98	CoaE-domain-containing protein. (239 aa)
	A0A2G4SZP1	Mitochondrial carrier; Belongs to the mitochondrial carrier (TC 2.A.29) family. (325 aa)
	A0A2G4SZV9	Monosaccharide transporter; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (510 aa)
	A0A2G4T0D8	DUF544-domain-containing protein. (319 aa)
	A0A2G4T0H7	Glutathione S-transferase; Belongs to the GST superfamily. (227 aa)
	A0A2G4T164	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (467 aa)
	A0A2G4T185	Molybdopterin binding protein. (254 aa)
	A0A2G4T191	MOSC domain-containing protein. (333 aa)
	A0A2G4T1L9	NAD(P)-binding protein. (311 aa)
	A0A2G4T1U1	Uncharacterized protein. (184 aa)
	A0A2G4T1Y1	Dihydrofolate reductase; Belongs to the dihydrofolate reductase family. (198 aa)
	A0A2G4T226	Uncharacterized protein. (652 aa)
	A0A2G4T2K8	DFP-domain-containing protein. (322 aa)
	A0A2G4T2K9	Riboflavin kinase. (173 aa)
	A0A2G4T2Q8	Mitochondrial substrate carrier; Belongs to the mitochondrial carrier (TC 2.A.29) family. (333 aa)
	A0A2G4T330	Uncharacterized protein. (695 aa)
	A0A2G4T353	GST N-terminal domain-containing protein. (323 aa)
	A0A2G4T399	ATP-NAD kinase. (600 aa)
	A0A2G4T3C6	Uncharacterized protein. (220 aa)
	A0A2G4T3P1	Rhodanese-like protein. (430 aa)
	A0A2G4T3X3	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (598 aa)
	A0A2G4T432	Mitochondrial carrier; Belongs to the mitochondrial carrier (TC 2.A.29) family. (338 aa)
	A0A2G4T4D3	Metallo-dependent phosphatase; Belongs to the 5'-nucleotidase family. (676 aa)
	A0A2G4T4I1	Molybdopterin synthase catalytic subunit; Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group. (147 aa)
	A0A2G4T4P6	5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (208 aa)
	A0A2G4T4S2	Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. (293 aa)
	A0A2G4T4U3	Nicotinamide-nucleotide adenylyltransferase; Belongs to the eukaryotic NMN adenylyltransferase family. (253 aa)
	A0A2G4T524	Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. (498 aa)
	A0A2G4T527	Molybdopterin binding protein. (255 aa)
	A0A2G4T6G5	Monosaccharide transporter; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (509 aa)
	A0A2G4T6S7	Acetyl-CoA carboxylase. (2216 aa)
	A0A2G4T7C0	MFS general substrate transporter. (516 aa)
	A0A2G4T7I5	NAD(P)-binding protein. (307 aa)
	A0A2G4T7N2	Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. (413 aa)
	A0A2G4T8D0	Rhodanese-like protein. (314 aa)
	A0A2G4T944	Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase. (390 aa)
	A0A2G4T9X6	ATP-NAD kinase. (411 aa)
	A0A2G4TBC8	MFS domain-containing protein; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (1013 aa)
	A0A2G4SKW1	P-loop containing nucleoside triphosphate hydrolase protein. (207 aa)
	A0A2G4SKR1	Uncharacterized protein. (578 aa)
	A0A2G4SKC5	Nucleotidylyl transferase. (172 aa)
	A0A2G4SK31	Fumble. (369 aa)
	A0A2G4SJZ6	Phosphodiest-domain-containing protein. (503 aa)
	A0A2G4SIY9	Uncharacterized protein. (629 aa)
	A0A2G4SIV0	Molybdenum cofactor biosynthesis protein 1 B. (487 aa)
	A0A2G4SIC4	Adenine nucleotide alpha hydrolases-like protein. (220 aa)
	A0A2G4SI40	Bifunctional protein. (298 aa)
	A0A2G4SHS2	Thiamine pyrophosphokinase; Belongs to the thiamine pyrophosphokinase family. (250 aa)
	A0A2G4SHP8	Acetyl-CoA carboxylase. (546 aa)
	A0A2G4SHM7	Corrinoid adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family. (165 aa)
	A0A2G4SHL6	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (467 aa)
	A0A2G4SGR6	Xanthine/uracil permease. (604 aa)
	A0A2G4SGM7	FSH1 domain-containing protein. (209 aa)
	A0A2G4SGG1	Nicotinamide-nucleotide adenylyltransferase; Belongs to the eukaryotic NMN adenylyltransferase family. (270 aa)
	A0A2G4SFU6	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1178 aa)
	A0A2G4SFK2	Mitochondrial carrier; Belongs to the mitochondrial carrier (TC 2.A.29) family. (305 aa)
	A0A2G4SF73	Purine permease. (602 aa)
	A0A2G4SF29	Class II aaRS and biotin synthetase. (630 aa)
	A0A2G4SEI6	Glutathione S-transferase. (216 aa)

Your Current Organism:

Rhizopus microsporus

NCBI taxonomy Id: 1340429
Other names: R. microsporus ATCC 52813, Rhizopus microsporus ATCC 52813

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A2G4SF29	A0A2G4SFU6	A0A2G4SF29	A0A2G4SFU6	Class II aaRS and biotin synthetase.	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	0.769
A0A2G4SF29	A0A2G4SHP8	A0A2G4SF29	A0A2G4SHP8	Class II aaRS and biotin synthetase.	Acetyl-CoA carboxylase.	0.709
A0A2G4SF29	A0A2G4SIY9	A0A2G4SF29	A0A2G4SIY9	Class II aaRS and biotin synthetase.	Uncharacterized protein.	0.752
A0A2G4SF29	A0A2G4SMD2	A0A2G4SF29	A0A2G4SMD2	Class II aaRS and biotin synthetase.	Propionyl-CoA carboxylase.	0.709
A0A2G4SF29	A0A2G4SMG5	A0A2G4SF29	A0A2G4SMG5	Class II aaRS and biotin synthetase.	Uncharacterized protein.	0.688
A0A2G4SF29	A0A2G4SNH2	A0A2G4SF29	A0A2G4SNH2	Class II aaRS and biotin synthetase.	Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family.	0.481
A0A2G4SF29	A0A2G4STQ9	A0A2G4SF29	A0A2G4STQ9	Class II aaRS and biotin synthetase.	Carboxyl transferase.	0.709
A0A2G4SF29	A0A2G4SXS1	A0A2G4SF29	A0A2G4SXS1	Class II aaRS and biotin synthetase.	Carboxyl transferase.	0.709
A0A2G4SF29	A0A2G4SY91	A0A2G4SF29	A0A2G4SY91	Class II aaRS and biotin synthetase.	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	0.571
A0A2G4SF29	A0A2G4T1Y1	A0A2G4SF29	A0A2G4T1Y1	Class II aaRS and biotin synthetase.	Dihydrofolate reductase; Belongs to the dihydrofolate reductase family.	0.571
A0A2G4SF29	A0A2G4T226	A0A2G4SF29	A0A2G4T226	Class II aaRS and biotin synthetase.	Uncharacterized protein.	0.688
A0A2G4SF29	A0A2G4T2K8	A0A2G4SF29	A0A2G4T2K8	Class II aaRS and biotin synthetase.	DFP-domain-containing protein.	0.726
A0A2G4SF29	A0A2G4T330	A0A2G4SF29	A0A2G4T330	Class II aaRS and biotin synthetase.	Uncharacterized protein.	0.688
A0A2G4SF29	A0A2G4T6S7	A0A2G4SF29	A0A2G4T6S7	Class II aaRS and biotin synthetase.	Acetyl-CoA carboxylase.	0.851
A0A2G4SFU6	A0A2G4SF29	A0A2G4SFU6	A0A2G4SF29	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	Class II aaRS and biotin synthetase.	0.769
A0A2G4SFU6	A0A2G4SHP8	A0A2G4SFU6	A0A2G4SHP8	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	Acetyl-CoA carboxylase.	0.783
A0A2G4SFU6	A0A2G4SIY9	A0A2G4SFU6	A0A2G4SIY9	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	Uncharacterized protein.	0.748
A0A2G4SFU6	A0A2G4SMD2	A0A2G4SFU6	A0A2G4SMD2	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	Propionyl-CoA carboxylase.	0.810
A0A2G4SFU6	A0A2G4SMG5	A0A2G4SFU6	A0A2G4SMG5	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	Uncharacterized protein.	0.713
A0A2G4SFU6	A0A2G4SP60	A0A2G4SFU6	A0A2G4SP60	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	Class II aaRS and biotin synthetase.	0.769