STRINGSTRING
A0A3F3Q5Y8 A0A3F3Q5Y8 A0A3F3QIA2 A0A3F3QIA2 A0A3F3QIF4 A0A3F3QIF4 A0A3F3QIM6 A0A3F3QIM6 A0A3F3QIR2 A0A3F3QIR2 A0A3F3QIW4 A0A3F3QIW4 A0A3F3QJ09 A0A3F3QJ09 A0A3F3QJ19 A0A3F3QJ19 SLX4 SLX4 A0A3F3QJK8 A0A3F3QJK8 A0A3F3QKM2 A0A3F3QKM2 A0A3F3QKS1 A0A3F3QKS1 A0A3F3QLC7 A0A3F3QLC7 A0A3F3QI67 A0A3F3QI67 A0A3F3QFT7 A0A3F3QFT7 A0A3F3QGM4 A0A3F3QGM4 A0A3F3QI36 A0A3F3QI36 A0A3F3QHM3 A0A3F3QHM3 A0A3F3QHD8 A0A3F3QHD8 A0A3F3QH94 A0A3F3QH94 A0A3F3QH71 A0A3F3QH71 A0A3F3QH54 A0A3F3QH54 A0A3F3PHV2 A0A3F3PHV2 A0A3F3PKH7 A0A3F3PKH7 A0A3F3PL36 A0A3F3PL36 A0A3F3PL38 A0A3F3PL38 A0A3F3PLP1 A0A3F3PLP1 A0A3F3PMT7 A0A3F3PMT7 A0A3F3PN32 A0A3F3PN32 A0A3F3PNZ9 A0A3F3PNZ9 A0A3F3PQA1 A0A3F3PQA1 A0A3F3PQZ5 A0A3F3PQZ5 A0A3F3PR65 A0A3F3PR65 A0A3F3PSU9 A0A3F3PSU9 A0A3F3PSW9 A0A3F3PSW9 A0A3F3PT54 A0A3F3PT54 A0A3F3PT93 A0A3F3PT93 A0A3F3PTY6 A0A3F3PTY6 A0A3F3PTY8 A0A3F3PTY8 A0A3F3PU45 A0A3F3PU45 A0A3F3PU55 A0A3F3PU55 A0A3F3PUB6 A0A3F3PUB6 A0A3F3PUG0 A0A3F3PUG0 A0A3F3PUI8 A0A3F3PUI8 A0A3F3PUM8 A0A3F3PUM8 A0A3F3PVK7 A0A3F3PVK7 A0A3F3PWP6 A0A3F3PWP6 A0A3F3PWZ3 A0A3F3PWZ3 A0A3F3PX30 A0A3F3PX30 A0A3F3PYB0 A0A3F3PYB0 A0A3F3PYC6 A0A3F3PYC6 A0A3F3PYN2 A0A3F3PYN2 A0A3F3PZ42 A0A3F3PZ42 A0A3F3Q0D7 A0A3F3Q0D7 A0A3F3Q0Q7 A0A3F3Q0Q7 SLX1 SLX1 A0A3F3Q175 A0A3F3Q175 A0A3F3Q1V4 A0A3F3Q1V4 A0A3F3Q290 A0A3F3Q290 A0A3F3Q294 A0A3F3Q294 A0A3F3Q2C7 A0A3F3Q2C7 A0A3F3Q2X5 A0A3F3Q2X5 A0A3F3Q3E1 A0A3F3Q3E1 A0A3F3Q3W6 A0A3F3Q3W6 A0A3F3Q403 A0A3F3Q403 A0A3F3Q4C6 A0A3F3Q4C6 A0A3F3Q4Q9 A0A3F3Q4Q9 A0A3F3Q4U5 A0A3F3Q4U5 A0A3F3Q4V1 A0A3F3Q4V1 A0A3F3Q501 A0A3F3Q501 A0A3F3QFI6 A0A3F3QFI6 A0A3F3QF50 A0A3F3QF50 A0A3F3QEW0 A0A3F3QEW0 A0A3F3QEC4 A0A3F3QEC4 KAE1 KAE1 A0A3F3QDW8 A0A3F3QDW8 A0A3F3QDS4 A0A3F3QDS4 A0A3F3QDQ6 A0A3F3QDQ6 A0A3F3QD28 A0A3F3QD28 A0A3F3QD16 A0A3F3QD16 A0A3F3QD11 A0A3F3QD11 A0A3F3QCV8 A0A3F3QCV8 A0A3F3QCT0 A0A3F3QCT0 A0A3F3QCH3 A0A3F3QCH3 A0A3F3QBW0 A0A3F3QBW0 A0A3F3QA68 A0A3F3QA68 A0A3F3Q9G0 A0A3F3Q9G0 A0A3F3Q8T4 A0A3F3Q8T4 A0A3F3Q8N1 A0A3F3Q8N1 A0A3F3Q8L9 A0A3F3Q8L9 A0A3F3Q8B8 A0A3F3Q8B8 A0A3F3Q7Y4 A0A3F3Q7Y4 A0A3F3Q7W6 A0A3F3Q7W6 A0A3F3Q7W3 A0A3F3Q7W3 A0A3F3Q6S5 A0A3F3Q6S5 A0A3F3Q6R1 A0A3F3Q6R1 A0A3F3Q6I7 A0A3F3Q6I7 A0A3F3Q622 A0A3F3Q622 MCM7 MCM7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
A0A3F3Q5Y8Muts domain V-domain-containing protein. (1653 aa)
A0A3F3QIA2Kinase-like domain-containing protein. (376 aa)
A0A3F3QIF4SIR2 family histone deacetylase. (612 aa)
A0A3F3QIM6DSS1/SEM1 family-domain-containing protein. (88 aa)
A0A3F3QIR2Uncharacterized protein. (363 aa)
A0A3F3QIW4DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (629 aa)
A0A3F3QJ09Uncharacterized protein. (275 aa)
A0A3F3QJ19P-loop containing nucleoside triphosphate hydrolase protein. (577 aa)
SLX4Structure-specific endonuclease subunit SLX4; Regulatory subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (830 aa)
A0A3F3QJK8ATP-dependent DNA helicase II subunit 2; Single-stranded DNA-dependent ATP-dependent helicase. (714 aa)
A0A3F3QKM2Uncharacterized protein. (403 aa)
A0A3F3QKS1Non-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids. (444 aa)
A0A3F3QLC7Sld5 domain-containing protein. (178 aa)
A0A3F3QI67DNA mismatch repair protein Msh5. (920 aa)
A0A3F3QFT7Transcriptional regulation of mitochondrial recombination-domain-containing protein. (350 aa)
A0A3F3QGM4Kinetochore component CENP-S-domain-containing protein. (102 aa)
A0A3F3QI36DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily. (347 aa)
A0A3F3QHM3DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1708 aa)
A0A3F3QHD8DNA helicase; Belongs to the MCM family. (961 aa)
A0A3F3QH94Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (797 aa)
A0A3F3QH71RPA_C domain-containing protein. (288 aa)
A0A3F3QH54SNF2 family N-terminal domain-domain-containing protein. (892 aa)
A0A3F3PHV2Uncharacterized protein. (226 aa)
A0A3F3PKH7Uncharacterized protein. (197 aa)
A0A3F3PL36Uncharacterized protein. (200 aa)
A0A3F3PL38Kinase-like domain-containing protein. (491 aa)
A0A3F3PLP1DNA ligase. (1009 aa)
A0A3F3PMT7Uncharacterized protein. (555 aa)
A0A3F3PN32DUF1767 domain-containing protein. (237 aa)
A0A3F3PNZ9Ribonuclease H-like domain-containing protein. (458 aa)
A0A3F3PQA1DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1118 aa)
A0A3F3PQZ5Uncharacterized protein. (1024 aa)
A0A3F3PR65WD domain protein. (409 aa)
A0A3F3PSU9Rec8 like protein-domain-containing protein. (589 aa)
A0A3F3PSW9Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (606 aa)
A0A3F3PT54Mitochondrial genome maintenance MGM101. (265 aa)
A0A3F3PT93Kinase-like domain-containing protein. (365 aa)
A0A3F3PTY6ERCC4 domain-containing protein. (977 aa)
A0A3F3PTY8AAA_23 domain-containing protein. (339 aa)
A0A3F3PU45DNA_LIGASE_A3 domain-containing protein. (1063 aa)
A0A3F3PU55DNA helicase; Belongs to the MCM family. (720 aa)
A0A3F3PUB6DNA ligase. (834 aa)
A0A3F3PUG0Transcriptional adapter 2; Functions as component of the transcription regulatory histone acetylation (HAT) complexes SAGA, SALSA and ADA. SAGA is involved in RNA polymerase II-dependent transcriptional regulation. (520 aa)
A0A3F3PUI8Cenp-O kinetochore centromere component-domain-containing protein. (356 aa)
A0A3F3PUM8CDC45 family. (860 aa)
A0A3F3PVK7Uncharacterized protein. (374 aa)
A0A3F3PWP6Sister chromatid cohesion protein. (1772 aa)
A0A3F3PWZ3P-loop containing nucleoside triphosphate hydrolase protein. (1441 aa)
A0A3F3PX30Vacuolar protein 14 C-terminal Fig4p binding-domain-containing protein. (1756 aa)
A0A3F3PYB0MAGE-domain-containing protein. (344 aa)
A0A3F3PYC6DNA polymerase. (1668 aa)
A0A3F3PYN2Uncharacterized protein. (712 aa)
A0A3F3PZ42Mus7/MMS22 family-domain-containing protein. (2391 aa)
A0A3F3Q0D7Uncharacterized protein. (240 aa)
A0A3F3Q0Q7DNA helicase; Belongs to the MCM family. (898 aa)
SLX1Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (424 aa)
A0A3F3Q175Nse1 non-SMC component of SMC5-6 complex-domain-containing protein. (394 aa)
A0A3F3Q1V4Spo11/DNA topoisomerase VI subunit A. (395 aa)
A0A3F3Q290Mono-functional DNA-alkylating methyl methanesulfonate N-term-domain-containing protein. (1278 aa)
A0A3F3Q294DNA helicase; Belongs to the MCM family. (887 aa)
A0A3F3Q2C7SNF2 family N-terminal domain-domain-containing protein. (1008 aa)
A0A3F3Q2X5Meiotic nuclear division protein 1; Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis. Belongs to the MND1 family. (231 aa)
A0A3F3Q3E1Uncharacterized protein. (234 aa)
A0A3F3Q3W6Crossover junction endonuclease mus81. (583 aa)
A0A3F3Q403Rad2-like endonuclease. (875 aa)
A0A3F3Q4C6DNA polymerase subunit Cdc27. (447 aa)
A0A3F3Q4Q9Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (851 aa)
A0A3F3Q4U5Uncharacterized protein. (577 aa)
A0A3F3Q4V1ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (541 aa)
A0A3F3Q501Mating-type switching protein Swi10. (327 aa)
A0A3F3QFI6Pkinase-domain-containing protein. (1141 aa)
A0A3F3QF50SPOC like C-terminal domain-containing protein. (653 aa)
A0A3F3QEW0Replication factor A protein 3. (122 aa)
A0A3F3QEC4Uncharacterized protein. (751 aa)
KAE1tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. KAE1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. Th [...] (361 aa)
A0A3F3QDW8Aldehyde/histidinol dehydrogenase; Belongs to the aldehyde dehydrogenase family. (631 aa)
A0A3F3QDS4Pachytene checkpoint component Pch2; Belongs to the AAA ATPase family. (486 aa)
A0A3F3QDQ6Checkpoint protein; Belongs to the HUS1 family. (363 aa)
A0A3F3QD28RING-type domain-containing protein. (272 aa)
A0A3F3QD16Muts domain V-domain-containing protein. (920 aa)
A0A3F3QD11Rad1/Rec1/Rad17. (376 aa)
A0A3F3QCV8Sld5 domain-containing protein. (223 aa)
A0A3F3QCT0Uncharacterized protein. (77 aa)
A0A3F3QCH3Uncharacterized protein. (156 aa)
A0A3F3QBW0Zinc-finger of the MIZ type in Nse subunit-domain-containing protein. (541 aa)
A0A3F3QA68ATP-dependent DNA helicase. (1568 aa)
A0A3F3Q9G0Rad51-domain-containing protein; Belongs to the RecA family. (337 aa)
A0A3F3Q8T4Endonuclease. (334 aa)
A0A3F3Q8N1DNA ligase. (884 aa)
A0A3F3Q8L9DNA helicase; Belongs to the MCM family. (958 aa)
A0A3F3Q8B8Thermolysin metallopeptidase. (369 aa)
A0A3F3Q7Y4Putative DNA helicase ino80. (1697 aa)
A0A3F3Q7W6S-adenosyl-L-methionine-dependent methyltransferase. (346 aa)
A0A3F3Q7W3Swi5-domain-containing protein. (107 aa)
A0A3F3Q6S5Histidine kinase-like ATPase. (730 aa)
A0A3F3Q6R1Pkinase-domain-containing protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (2165 aa)
A0A3F3Q6I7Serine/threonine-protein phosphatase. (426 aa)
A0A3F3Q622Uncharacterized protein. (759 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (807 aa)
Your Current Organism:
Aspergillus welwitschiae
NCBI taxonomy Id: 1341132
Other names: A. welwitschiae, Aspergillus welwitschiae (Bres.) Henn., CBS 139.54, Ustilago welwitschiae
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