(73 nodes) Actin cytoskeleton network (Aspergillus welwitschiae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A3F3PYK1	Lanthionine synthetase C family protein. (528 aa)
	A0A3F3QBB7	Zn(2)-C6 fungal-type domain-containing protein. (803 aa)
	A0A3F3QAR3	VHS domain protein. (399 aa)
	A0A3F3QAH9	Uncharacterized protein. (647 aa)
	A0A3F3QAC4	F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (272 aa)
	A0A3F3QA79	Calponin homology domain-containing protein. (644 aa)
	A0A3F3Q9L1	Fungal-specific transcription factor domain-domain-containing protein. (584 aa)
	A0A3F3Q983	Nucleotide-diphospho-sugar transferase. (514 aa)
	A0A3F3Q889	FCH-domain-containing protein. (743 aa)
	A0A3F3Q863	P-loop containing nucleoside triphosphate hydrolase protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1572 aa)
	A0A3F3Q858	Kinase-like domain-containing protein. (996 aa)
	A0A3F3Q810	Actin family; Belongs to the actin family. (439 aa)
	A0A3F3Q710	EH domain-containing protein. (559 aa)
	A0A3F3Q6V9	SH3 protein. (998 aa)
	A0A3F3Q6V8	Uncharacterized protein. (368 aa)
	A0A3F3Q5F9	SH3 domain-containing protein. (1216 aa)
	A0A3F3Q4E5	Uncharacterized protein. (341 aa)
	A0A3F3Q4D2	Trimeric LpxA-like protein. (203 aa)
	A0A3F3Q459	Sulfate transporter family-domain-containing protein. (730 aa)
	A0A3F3Q436	Actin-like ATPase domain-containing protein; Belongs to the actin family. (569 aa)
	A0A3F3Q419	Uncharacterized protein. (346 aa)
	A0A3F3Q1B2	ADF-H domain-containing protein. (141 aa)
	A0A3F3Q0V9	Putative zinc finger in N-recognin-domain-containing protein. (546 aa)
	A0A3F3Q0F4	SH3 domain-containing protein. (1301 aa)
	A0A3F3PZL6	Coronin; Belongs to the WD repeat coronin family. (595 aa)
	A0A3F3PZA9	Chitin synthase-domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1760 aa)
	A0A3F3PZ98	Chitin synthase-domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1854 aa)
	A0A3F3PYN5	Putative actin-related protein 2/3 complex subunit 1A. (668 aa)
	A0A3F3QBF5	Uncharacterized protein. (464 aa)
	A0A3F3PYA4	PKS_ER domain-containing protein. (809 aa)
	A0A3F3PXZ5	Uncharacterized protein. (222 aa)
	A0A3F3PXB4	Uncharacterized protein. (672 aa)
	A0A3F3PVV7	Peptidase family M3-domain-containing protein. (716 aa)
	A0A3F3PVM7	Myosin regulatory light chain cdc4. (149 aa)
	A0A3F3PVE2	Glycoside hydrolase superfamily; Belongs to the glycosyl hydrolase 5 (cellulase A) family. (385 aa)
	A0A3F3PUK5	RRM domain-containing protein. (570 aa)
	A0A3F3PUB7	Altered inheritance of mitochondria protein 21. (949 aa)
	A0A3F3PUB0	Dynactin p62 family-domain-containing protein. (678 aa)
	A0A3F3PU31	Non-specific serine/threonine protein kinase. (640 aa)
	A0A3F3PTY9	Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family. (169 aa)
	A0A3F3PS95	Vacuolar ATP synthase catalytic subunit A; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (1378 aa)
	A0A3F3PRT4	Calponin homology domain-containing protein. (644 aa)
	A0A3F3PRD4	Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (188 aa)
	A0A3F3PQZ6	Glycoside hydrolase superfamily; Belongs to the glycosyl hydrolase 5 (cellulase A) family. (386 aa)
	A0A3F3PQ73	Tropomyosin. (154 aa)
	A0A3F3PNC3	DNase I-like protein. (1094 aa)
	A0A3F3PNA9	Uncharacterized protein. (1464 aa)
	A0A3F3PL76	Uncharacterized protein. (409 aa)
	A0A3F3PKA9	Glycoside hydrolase superfamily; Belongs to the glycosyl hydrolase 5 (cellulase A) family. (416 aa)
	A0A3F3PI10	Uncharacterized protein. (294 aa)
	A0A3F3QKI6	Uncharacterized protein. (709 aa)
	A0A3F3QKF1	Uncharacterized protein. (915 aa)
	A0A3F3QJZ5	Myosin_tail_1 domain-containing protein. (1046 aa)
	A0A3F3QJU9	C2 domain-containing protein. (790 aa)
	A0A3F3QIR3	Uncharacterized protein. (1801 aa)
	A0A3F3QI40	Transport protein Avl9-domain-containing protein. (788 aa)
	A0A3F3QHP4	Uncharacterized protein. (659 aa)
	A0A3F3QHL8	WH2 domain-containing protein. (453 aa)
	A0A3F3QH28	Actin cytoskeleton-regulatory complex protein end3. (404 aa)
	A0A3F3QGZ4	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (388 aa)
	A0A3F3QGP5	Uncharacterized protein. (435 aa)
	A0A3F3QG29	Methyltransferase-like protein; Belongs to the methyltransferase superfamily. METL family. (377 aa)
	A0A3F3QF56	P-loop containing nucleoside triphosphate hydrolase protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1266 aa)
	A0A3F3QEZ5	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (266 aa)
	A0A3F3QE38	Calponin-homology (CH) domain-containing protein. (602 aa)
	A0A3F3QDZ6	Uncharacterized protein. (808 aa)
	A0A3F3QDX2	Peptidase_M3 domain-containing protein. (760 aa)
	A0A3F3QDR2	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (320 aa)
	A0A3F3QD59	UBA/TS-N domain protein. (1277 aa)
	A0A3F3QD45	Uncharacterized protein. (1018 aa)
	A0A3F3QCY7	Dynamitin-domain-containing protein. (477 aa)
	A0A3F3QCW3	TGc domain-containing protein. (705 aa)
	A0A3F3QCV9	Uncharacterized protein. (193 aa)

Your Current Organism:

Aspergillus welwitschiae

NCBI taxonomy Id: 1341132
Other names: A. welwitschiae, Aspergillus welwitschiae (Bres.) Henn., CBS 139.54, Ustilago welwitschiae

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A3F3PI10	A0A3F3PQ73	Uncharacterized protein.	Tropomyosin.	0.940
A0A3F3PI10	A0A3F3PRT4	Uncharacterized protein.	Calponin homology domain-containing protein.	0.799
A0A3F3PI10	A0A3F3PVM7	Uncharacterized protein.	Myosin regulatory light chain cdc4.	0.826
A0A3F3PI10	A0A3F3Q419	Uncharacterized protein.	Uncharacterized protein.	0.641
A0A3F3PI10	A0A3F3Q436	Uncharacterized protein.	Actin-like ATPase domain-containing protein; Belongs to the actin family.	0.778
A0A3F3PI10	A0A3F3Q6V9	Uncharacterized protein.	SH3 protein.	0.528
A0A3F3PI10	A0A3F3Q810	Uncharacterized protein.	Actin family; Belongs to the actin family.	0.700
A0A3F3PI10	A0A3F3Q863	Uncharacterized protein.	P-loop containing nucleoside triphosphate hydrolase protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.697
A0A3F3PI10	A0A3F3QA79	Uncharacterized protein.	Calponin homology domain-containing protein.	0.522
A0A3F3PI10	A0A3F3QCW3	Uncharacterized protein.	TGc domain-containing protein.	0.441
A0A3F3PI10	A0A3F3QDZ6	Uncharacterized protein.	Uncharacterized protein.	0.840
A0A3F3PI10	A0A3F3QE38	Uncharacterized protein.	Calponin-homology (CH) domain-containing protein.	0.787
A0A3F3PI10	A0A3F3QF56	Uncharacterized protein.	P-loop containing nucleoside triphosphate hydrolase protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.667
A0A3F3PI10	A0A3F3QGZ4	Uncharacterized protein.	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.	0.648
A0A3F3PI10	A0A3F3QIR3	Uncharacterized protein.	Uncharacterized protein.	0.781
A0A3F3PI10	A0A3F3QJU9	Uncharacterized protein.	C2 domain-containing protein.	0.557
A0A3F3PI10	A0A3F3QJZ5	Uncharacterized protein.	Myosin_tail_1 domain-containing protein.	0.995
A0A3F3PNA9	A0A3F3QE38	Uncharacterized protein.	Calponin-homology (CH) domain-containing protein.	0.409
A0A3F3PNC3	A0A3F3PS95	DNase I-like protein.	Vacuolar ATP synthase catalytic subunit A; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.413
A0A3F3PNC3	A0A3F3Q436	DNase I-like protein.	Actin-like ATPase domain-containing protein; Belongs to the actin family.	0.407