(38 nodes) Mixed, incl. Tetracycline repressor TetR, C-terminal, and Flavin-dependent monooxygenase TetX network (Streptomyces rapamycinicus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AGP52077.1	FAD-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (377 aa)
	AGP52708.1	Monooxygenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (380 aa)
	AGP52725.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (393 aa)
	AGP52952.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (540 aa)
	AGP52953.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (198 aa)
	AGP53052.1	TetR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (221 aa)
	AGP53454.1	Transcriptional regulator; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (223 aa)
	AGP53593.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (236 aa)
	AGP53594.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (205 aa)
	AGP54175.1	TetR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (248 aa)
	AGP54176.1	FAD-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (393 aa)
	AGP54177.1	Hydrolase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (276 aa)
	AGP55983.1	DNA damage-inducible protein DinB; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (178 aa)
	AGP56088.1	TetR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (249 aa)
	AGP56665.1	TetR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (266 aa)
	AGP58154.1	FAD-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (379 aa)
	AGP58155.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (269 aa)
	AGP58362.1	Amidohydrolase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (348 aa)
	AGP58363.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (248 aa)
	AGP59175.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (374 aa)
	AGP59212.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (331 aa)
	AGP59444.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (257 aa)
	AGP59536.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (389 aa)
	AGP59585.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (373 aa)
	AGP59822.1	Translation initiation factor IF-2; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (263 aa)
	AGP59923.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (403 aa)
	AGP59924.1	TetR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (262 aa)
	AGP60185.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (198 aa)
	AGP60186.1	Oxidoreductase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (419 aa)
	AGP60611.1	Tetracycline repressor; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (254 aa)
	AGP60934.1	Major facilitator transporter; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (513 aa)
	AGP60935.1	TetR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (250 aa)
	AGP60936.1	acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (350 aa)
	AGP61099.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (717 aa)
	AGP61100.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (300 aa)
	AGP61101.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (250 aa)
	AGP61174.1	Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (254 aa)
	AGP61175.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the LysR transcriptional regulatory family. (701 aa)

Your Current Organism:

Streptomyces rapamycinicus

NCBI taxonomy Id: 1343740
Other names: S. rapamycinicus NRRL 5491, Streptomyces rapamycinicus NRRL 5491

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGP52077.1	AGP52725.1	M271_02215	M271_05495	FAD-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.624
AGP52077.1	AGP54175.1	M271_02215	M271_12905	FAD-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	TetR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.499
AGP52077.1	AGP58155.1	M271_02215	M271_33705	FAD-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.682
AGP52077.1	AGP59175.1	M271_02215	M271_38935	FAD-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.530
AGP52077.1	AGP59822.1	M271_02215	M271_42235	FAD-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Translation initiation factor IF-2; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.404
AGP52708.1	AGP54176.1	M271_05405	M271_12910	Monooxygenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	FAD-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.593
AGP52708.1	AGP59585.1	M271_05405	M271_41040	Monooxygenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.563
AGP52708.1	AGP61175.1	M271_05405	M271_49065	Monooxygenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the LysR transcriptional regulatory family.	0.476
AGP52725.1	AGP52077.1	M271_05495	M271_02215	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	FAD-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.624
AGP52725.1	AGP54176.1	M271_05495	M271_12910	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	FAD-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.636
AGP52725.1	AGP58154.1	M271_05495	M271_33700	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	FAD-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.581
AGP52725.1	AGP59536.1	M271_05495	M271_40790	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.433
AGP52725.1	AGP59585.1	M271_05495	M271_41040	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.603
AGP52725.1	AGP59822.1	M271_05495	M271_42235	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Translation initiation factor IF-2; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.531
AGP52725.1	AGP61175.1	M271_05495	M271_49065	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the LysR transcriptional regulatory family.	0.569
AGP52952.1	AGP52953.1	M271_06640	M271_06645	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.675
AGP52952.1	AGP59175.1	M271_06640	M271_38935	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.487
AGP52953.1	AGP52952.1	M271_06645	M271_06640	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.675
AGP52953.1	AGP53052.1	M271_06645	M271_07150	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	TetR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.485
AGP52953.1	AGP53454.1	M271_06645	M271_09205	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Transcriptional regulator; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.613