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AGP52624.1 AGP52624.1 AGP53153.1 AGP53153.1 AGP53317.1 AGP53317.1 AGP53544.1 AGP53544.1 AGP53545.1 AGP53545.1 dxs dxs AGP53831.1 AGP53831.1 AGP53832.1 AGP53832.1 AGP53833.1 AGP53833.1 AGP53834.1 AGP53834.1 AGP53835.1 AGP53835.1 AGP53836.1 AGP53836.1 AGP53837.1 AGP53837.1 AGP53838.1 AGP53838.1 AGP53850.1 AGP53850.1 AGP53851.1 AGP53851.1 AGP53852.1 AGP53852.1 AGP53853.1 AGP53853.1 AGP53854.1 AGP53854.1 AGP53855.1 AGP53855.1 AGP53856.1 AGP53856.1 idi idi dxs-2 dxs-2 AGP54670.1 AGP54670.1 AGP54671.1 AGP54671.1 AGP54672.1 AGP54672.1 dxr dxr AGP54674.1 AGP54674.1 AGP54675.1 AGP54675.1 ispH ispH AGP55320.1 AGP55320.1 ispE ispE AGP55923.1 AGP55923.1 AGP56241.1 AGP56241.1 AGP56850.1 AGP56850.1 ispD ispD ispF ispF AGP57392.1 AGP57392.1 AGP57399.1 AGP57399.1 AGP57529.1 AGP57529.1 AGP57775.1 AGP57775.1 AGP57957.1 AGP57957.1 ispG ispG dxs-3 dxs-3 AGP59001.1 AGP59001.1 ispH-2 ispH-2 AGP60029.1 AGP60029.1 AGP60520.1 AGP60520.1 AGP60692.1 AGP60692.1 AGP60693.1 AGP60693.1 AGP60746.1 AGP60746.1 AGP60771.1 AGP60771.1 AGP60772.1 AGP60772.1 AGP60916.1 AGP60916.1 AGP61510.1 AGP61510.1 AGP61511.1 AGP61511.1 AGP61512.1 AGP61512.1 AGP61513.1 AGP61513.1 AGP61514.1 AGP61514.1 AGP61515.1 AGP61515.1 AGP61516.1 AGP61516.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AGP52624.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (524 aa)
AGP53153.1Di-trans,poly-cis-decaprenylcistransferase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (272 aa)
AGP53317.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (387 aa)
AGP53544.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (489 aa)
AGP53545.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (630 aa)
dxs1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (655 aa)
AGP53831.14-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (180 aa)
AGP53832.1Radical SAM protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (341 aa)
AGP53833.11-hydroxy-2-methyl-2-butenyl 4-diphosphate reductase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (253 aa)
AGP53834.1Squalene-hopene cyclase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (648 aa)
AGP53835.1Dimethylallyltranstransferase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the FPP/GGPP synthase family. (365 aa)
AGP53836.1Phytoene dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (477 aa)
AGP53837.1Phytoene synthase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (306 aa)
AGP53838.1Squalene synthase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (287 aa)
AGP53850.1Techoic acid ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (277 aa)
AGP53851.1ABC transporter; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (300 aa)
AGP53852.1Glycosyl transferase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (295 aa)
AGP53853.1Transferase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (242 aa)
AGP53854.1Dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (357 aa)
AGP53855.1Nucleotide sugar-1-phosphate transferase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (245 aa)
AGP53856.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (647 aa)
idiIsopentenyl-diphosphate delta-isomerase; Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP). (203 aa)
dxs-21-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (654 aa)
AGP54670.1Acetyltransferase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (189 aa)
AGP54671.1N-acetyltransferase GCN5; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (281 aa)
AGP54672.1Zinc metalloprotease; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (433 aa)
dxr1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (420 aa)
AGP54674.1acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (644 aa)
AGP54675.1LacI family transcriptional regulator; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (338 aa)
ispH4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (341 aa)
AGP55320.1UDP pyrophosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (253 aa)
ispE4-diphosphocytidyl-2C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (304 aa)
AGP55923.1Geranylgeranyl pyrophosphate synthase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the FPP/GGPP synthase family. (336 aa)
AGP56241.1Phytoene dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (483 aa)
AGP56850.1Geranylgeranyl pyrophosphate synthase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the FPP/GGPP synthase family. (324 aa)
ispD2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). (264 aa)
ispF2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (157 aa)
AGP57392.1Glycosyl transferase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (749 aa)
AGP57399.1Glycosyl transferase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (798 aa)
AGP57529.1Di-trans,poly-cis-decaprenylcistransferase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (259 aa)
AGP57775.1Polyprenyl diphosphate synthase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the FPP/GGPP synthase family. (331 aa)
AGP57957.1UDP pyrophosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (280 aa)
ispG4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (383 aa)
dxs-3Hypothetical protein; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (632 aa)
AGP59001.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the FPP/GGPP synthase family. (357 aa)
ispH-2Hypothetical protein; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (270 aa)
AGP60029.1Geranylgeranyl diphosphate synthase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the FPP/GGPP synthase family. (359 aa)
AGP60520.1Polyprenyl diphosphate synthase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the FPP/GGPP synthase family. (360 aa)
AGP60692.1FAD-binding monooxygenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (439 aa)
AGP60693.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (894 aa)
AGP60746.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (795 aa)
AGP60771.1Dimethylallyltranstransferase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the FPP/GGPP synthase family. (370 aa)
AGP60772.1Ubiquinone biosynthesis protein UbiA; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (373 aa)
AGP60916.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (302 aa)
AGP61510.12Fe-2S ferredoxin; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (335 aa)
AGP61511.1Phytoene synthase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (343 aa)
AGP61512.1Phytoene dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (588 aa)
AGP61513.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the FPP/GGPP synthase family. (404 aa)
AGP61514.1Lycopene cyclase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (432 aa)
AGP61515.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (242 aa)
AGP61516.1Isorenieratene synthase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (489 aa)
Your Current Organism:
Streptomyces rapamycinicus
NCBI taxonomy Id: 1343740
Other names: S. rapamycinicus NRRL 5491, Streptomyces rapamycinicus NRRL 5491
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