STRINGSTRING
AGP51744.1 AGP51744.1 AGP51761.1 AGP51761.1 AGP51763.1 AGP51763.1 AGP52245.1 AGP52245.1 AGP52319.1 AGP52319.1 AGP52503.1 AGP52503.1 AGP52629.1 AGP52629.1 AGP52738.1 AGP52738.1 AGP52860.1 AGP52860.1 AGP53031.1 AGP53031.1 pfkA pfkA AGP53341.1 AGP53341.1 AGP53527.1 AGP53527.1 AGP53999.1 AGP53999.1 AGP54017.1 AGP54017.1 AGP54292.1 AGP54292.1 AGP54327.1 AGP54327.1 pfkA-2 pfkA-2 AGP54936.1 AGP54936.1 AGP55289.1 AGP55289.1 glpX glpX pckG pckG AGP55639.1 AGP55639.1 AGP55726.1 AGP55726.1 AGP55731.1 AGP55731.1 AGP55914.1 AGP55914.1 AGP55915.1 AGP55915.1 AGP56265.1 AGP56265.1 AGP56267.1 AGP56267.1 AGP56458.1 AGP56458.1 AGP56459.1 AGP56459.1 AGP56470.1 AGP56470.1 AGP56471.1 AGP56471.1 AGP56472.1 AGP56472.1 pfp pfp acsA acsA AGP56875.1 AGP56875.1 gpmA gpmA AGP57018.1 AGP57018.1 AGP57028.1 AGP57028.1 AGP57246.1 AGP57246.1 eno eno AGP57483.1 AGP57483.1 AGP57777.1 AGP57777.1 AGP57810.1 AGP57810.1 AGP57988.1 AGP57988.1 AGP58045.1 AGP58045.1 AGP58072.1 AGP58072.1 AGP58104.1 AGP58104.1 AGP58225.1 AGP58225.1 AGP58244.1 AGP58244.1 AGP58368.1 AGP58368.1 AGP58501.1 AGP58501.1 AGP58504.1 AGP58504.1 AGP58547.1 AGP58547.1 pfp-2 pfp-2 AGP58676.1 AGP58676.1 gapA gapA pgk pgk tpiA tpiA pgi pgi AGP59282.1 AGP59282.1 AGP59751.1 AGP59751.1 AGP59839.1 AGP59839.1 AGP59864.1 AGP59864.1 AGP59982.1 AGP59982.1 AGP60113.1 AGP60113.1 AGP60261.1 AGP60261.1 gapA-2 gapA-2 AGP61043.1 AGP61043.1 AGP61080.1 AGP61080.1 AGP61081.1 AGP61081.1 AGP61082.1 AGP61082.1 AGP61144.1 AGP61144.1 AGP61398.1 AGP61398.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AGP51744.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (717 aa)
AGP51761.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (497 aa)
AGP51763.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (341 aa)
AGP52245.1Pyruvate dehydrogenase E1; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (783 aa)
AGP52319.1Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the aldehyde dehydrogenase family. (509 aa)
AGP52503.1Glyceraldehyde-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (484 aa)
AGP52629.1Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (466 aa)
AGP52738.1AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (537 aa)
AGP52860.1Fructose-bisphosphate aldolase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (279 aa)
AGP53031.16-phospho-beta-glucosidase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (450 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (341 aa)
AGP53341.1Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (346 aa)
AGP53527.1Catalyzes the oxidation of acetaldehyde, benzaldehyde, propionaldehyde and other aldehydes; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (507 aa)
AGP53999.1acetyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (568 aa)
AGP54017.1Pyruvate dehydrogenase E1; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (780 aa)
AGP54292.1Glucokinase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (384 aa)
AGP54327.1AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (565 aa)
pfkA-26-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (341 aa)
AGP54936.1Pyruvate kinase; Catalyzes the formation of phosphoenolpyruvate from pyruvate; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (475 aa)
AGP55289.1Polyphosphate glucokinase; Catalyzes the phosphorylation of glucose using polyphosphate or ATP as the phosphoryl donor; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (263 aa)
glpXType II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (343 aa)
pckGPhosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (629 aa)
AGP55639.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (310 aa)
AGP55726.1pimeloyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (749 aa)
AGP55731.1Molecular chaperone GroES; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (349 aa)
AGP55914.12-oxoglutarate ferredoxin oxidoreductase subunit alpha; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (650 aa)
AGP55915.12-oxoacid ferredoxin oxidoreductase subunit beta; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (360 aa)
AGP56265.1Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (340 aa)
AGP56267.1Aldose 1-epimerase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (271 aa)
AGP56458.12-oxoisovalerate dehydrogenase subunit beta; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (326 aa)
AGP56459.1Pyruvate dehydrogenase E1 subunit alpha; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (388 aa)
AGP56470.1Branched-chain alpha-keto acid dehydrogenase subunit E2; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (383 aa)
AGP56471.12-oxoisovalerate dehydrogenase subunit beta; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (349 aa)
AGP56472.1Pyruvate dehydrogenase E1 subunit alpha; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (380 aa)
pfp6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (341 aa)
acsAacetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (667 aa)
AGP56875.1Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the aldehyde dehydrogenase family. (485 aa)
gpmAPhosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (253 aa)
AGP57018.1Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (336 aa)
AGP57028.1ROK family transcriptional regulator; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (319 aa)
AGP57246.1Betaine-aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the aldehyde dehydrogenase family. (486 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (426 aa)
AGP57483.1Zinc-binding dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (349 aa)
AGP57777.1Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (340 aa)
AGP57810.16-phospho-beta-glucosidase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (420 aa)
AGP57988.1Pyruvate phosphate dikinase; Catalyzes the formation of phosphoenolpyruvate from pyruvate; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the PEP-utilizing enzyme family. (905 aa)
AGP58045.16-phospho-beta-glucosidase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (456 aa)
AGP58072.1Aldose 1-epimerase; Converts alpha-aldose to the beta-anomer. (389 aa)
AGP58104.1Pyruvate dehydrogenase E1; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (909 aa)
AGP58225.1Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the aldehyde dehydrogenase family. (488 aa)
AGP58244.1Molecular chaperone GroES; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (361 aa)
AGP58368.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (344 aa)
AGP58501.1Pyruvate dehydrogenase E1; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (891 aa)
AGP58504.1Dihydrolipoamide dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (462 aa)
AGP58547.1Glucokinase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (313 aa)
pfp-26-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (342 aa)
AGP58676.1Pyruvate kinase; Catalyzes the formation of phosphoenolpyruvate from pyruvate; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (467 aa)
gapAGlyceraldehyde-3-phosphate dehydrogenase; Required for glycolysis; catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (334 aa)
pgkPhosphoglycerate kinase; Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the phosphoglycerate kinase family. (400 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (251 aa)
pgiGlucose-6-phosphate isomerase; Functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the GPI family. (553 aa)
AGP59282.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the aldehyde dehydrogenase family. (512 aa)
AGP59751.16-phospho-beta-glucosidase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (436 aa)
AGP59839.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (351 aa)
AGP59864.1Glucose-6-phosphate isomerase; Catalyzes the formation of D-fructose 6-phosphate from D-glucose 6-phosphate; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (193 aa)
AGP59982.1ROK family transcriptional regulator; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (325 aa)
AGP60113.1PTS glucose transporter subunit IIA; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (148 aa)
AGP60261.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the aldehyde dehydrogenase family. (489 aa)
gapA-2Glyceraldehyde-3-phosphate dehydrogenase; Required for glycolysis; catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (332 aa)
AGP61043.1CoA-binding protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (691 aa)
AGP61080.1Pyruvate dehydrogenase E1 subunit alpha; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (363 aa)
AGP61081.12-oxoisovalerate dehydrogenase subunit beta; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (308 aa)
AGP61082.1Branched-chain alpha-keto acid dehydrogenase subunit E2; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (449 aa)
AGP61144.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (328 aa)
AGP61398.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the aldehyde dehydrogenase family. (524 aa)
Your Current Organism:
Streptomyces rapamycinicus
NCBI taxonomy Id: 1343740
Other names: S. rapamycinicus NRRL 5491, Streptomyces rapamycinicus NRRL 5491
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