STRINGSTRING
AGP51696.1 AGP51696.1 AGP51940.1 AGP51940.1 AGP52170.1 AGP52170.1 AGP51539.1 AGP51539.1 AGP52306.1 AGP52306.1 AGP52517.1 AGP52517.1 egtA egtA AGP53284.1 AGP53284.1 metK metK AGP53715.1 AGP53715.1 AGP54090.1 AGP54090.1 gshB gshB mmuM mmuM AGP54540.1 AGP54540.1 AGP54789.1 AGP54789.1 AGP54801.1 AGP54801.1 AGP54847.1 AGP54847.1 AGP54997.1 AGP54997.1 AGP55385.1 AGP55385.1 AGP55539.1 AGP55539.1 AGP55669.1 AGP55669.1 AGP55867.1 AGP55867.1 AGP51592.1 AGP51592.1 AGP56073.1 AGP56073.1 AGP56139.1 AGP56139.1 AGP56140.1 AGP56140.1 speE speE AGP56562.1 AGP56562.1 AGP51607.1 AGP51607.1 AGP56741.1 AGP56741.1 asd asd AGP56811.1 AGP56811.1 serC serC mdh mdh AGP51623.1 AGP51623.1 ahcY ahcY mtnA mtnA AGP51625.1 AGP51625.1 AGP57626.1 AGP57626.1 asd-2 asd-2 AGP59087.1 AGP59087.1 AGP59710.1 AGP59710.1 AGP59865.1 AGP59865.1 metE metE AGP60003.1 AGP60003.1 AGP60828.1 AGP60828.1 AGP61274.1 AGP61274.1 AGP61430.1 AGP61430.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AGP51696.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (743 aa)
AGP51940.1Cysteine synthase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (306 aa)
AGP52170.12-hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (317 aa)
AGP51539.1Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (475 aa)
AGP52306.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (400 aa)
AGP52517.1D-cysteine desulfhydrase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (351 aa)
egtAGlutamate--cysteine ligase; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low- molecular thiol compound ergothioneine. (418 aa)
AGP53284.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (407 aa)
metKS-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (402 aa)
AGP53715.1Class IV aminotransferase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (275 aa)
AGP54090.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (397 aa)
gshBHypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the prokaryotic GSH synthase family. (312 aa)
mmuMConverts homocysteine and S-adenosyl-methionine to methionine and S-adenosyl-homocysteine or S-methyl-methionine and homocysteine to two methionines; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (313 aa)
AGP54540.1Thiosulfate sulfurtransferase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (278 aa)
AGP54789.1Catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (361 aa)
AGP54801.13-phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (533 aa)
AGP54847.1Serine dehydratase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the iron-sulfur dependent L-serine dehydratase family. (460 aa)
AGP54997.1Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (430 aa)
AGP55385.1Cystathionine gamma-synthase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (387 aa)
AGP55539.15'-methylthioadenosine phosphorylase; Purine nucleoside phosphorylase involved in purine salvage. (281 aa)
AGP55669.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (336 aa)
AGP55867.1Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (420 aa)
AGP51592.1DNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (395 aa)
AGP56073.1Thiosulfate sulfurtransferase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (279 aa)
AGP56139.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (437 aa)
AGP56140.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (335 aa)
speESpermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine. (524 aa)
AGP56562.1Cystathionine gamma-lyase; Catalyzes the formation of cysteine and 2-oxobutanoate from cystathionine; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (404 aa)
AGP51607.1DNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (425 aa)
AGP56741.1Aspartokinase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the aspartokinase family. (426 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (363 aa)
AGP56811.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (436 aa)
serCPhosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (372 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (329 aa)
AGP51623.1Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (461 aa)
ahcYS-adenosyl-L-homocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. (485 aa)
mtnAInitiation factor 2B subunit alpha; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). (379 aa)
AGP51625.1DNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (425 aa)
AGP57626.1Adenosylhomocysteinase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (373 aa)
asd-2Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (341 aa)
AGP59087.1Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1167 aa)
AGP59710.12-hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (356 aa)
AGP59865.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (312 aa)
metE5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (772 aa)
AGP60003.1Cysteine synthase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (382 aa)
AGP60828.1Catalyzes conversion of 1-aminocyclopropane-1-carboxylate to ammonia and alpha-ketobutyrate; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (335 aa)
AGP61274.1TRZ/ATZ family hydrolase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (426 aa)
AGP61430.1Catalyzes conversion of 1-aminocyclopropane-1-carboxylate to ammonia and alpha-ketobutyrate; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (336 aa)
Your Current Organism:
Streptomyces rapamycinicus
NCBI taxonomy Id: 1343740
Other names: S. rapamycinicus NRRL 5491, Streptomyces rapamycinicus NRRL 5491
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