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AGP51740.1 AGP51740.1 AGP51741.1 AGP51741.1 AGP51744.1 AGP51744.1 AGP52629.1 AGP52629.1 AGP52640.1 AGP52640.1 AGP52738.1 AGP52738.1 AGP52886.1 AGP52886.1 AGP52893.1 AGP52893.1 AGP52945.1 AGP52945.1 AGP52946.1 AGP52946.1 AGP53081.1 AGP53081.1 AGP53329.1 AGP53329.1 AGP53878.1 AGP53878.1 AGP53879.1 AGP53879.1 AGP53999.1 AGP53999.1 AGP54004.1 AGP54004.1 AGP54010.1 AGP54010.1 AGP54031.1 AGP54031.1 AGP54066.1 AGP54066.1 AGP54067.1 AGP54067.1 sucD sucD sucC sucC AGP54210.1 AGP54210.1 AGP54271.1 AGP54271.1 AGP54327.1 AGP54327.1 AGP54685.1 AGP54685.1 AGP54934.1 AGP54934.1 ackA ackA AGP54942.1 AGP54942.1 AGP54957.1 AGP54957.1 AGP54958.1 AGP54958.1 AGP55263.1 AGP55263.1 AGP55726.1 AGP55726.1 acsA acsA AGP57081.1 AGP57081.1 AGP57084.1 AGP57084.1 AGP57138.1 AGP57138.1 sucC-2 sucC-2 sucD-2 sucD-2 AGP57187.1 AGP57187.1 AGP57298.1 AGP57298.1 AGP57661.1 AGP57661.1 AGP57736.1 AGP57736.1 AGP58214.1 AGP58214.1 AGP58461.1 AGP58461.1 AGP58504.1 AGP58504.1 AGP59890.1 AGP59890.1 AGP60045.1 AGP60045.1 AGP60048.1 AGP60048.1 AGP60206.1 AGP60206.1 AGP60212.1 AGP60212.1 AGP60215.1 AGP60215.1 AGP60219.1 AGP60219.1 AGP60222.1 AGP60222.1 AGP60306.1 AGP60306.1 AGP61043.1 AGP61043.1 AGP61192.1 AGP61192.1 AGP61193.1 AGP61193.1 AGP61263.1 AGP61263.1 AGP61411.1 AGP61411.1 AGP61467.1 AGP61467.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AGP51740.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the thiolase-like superfamily. Thiolase family. (387 aa)
AGP51741.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the enoyl-CoA hydratase/isomerase family. (249 aa)
AGP51744.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (717 aa)
AGP52629.1Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (466 aa)
AGP52640.14-aminobutyrate aminotransferase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (419 aa)
AGP52738.1AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (537 aa)
AGP52886.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the thiolase-like superfamily. Thiolase family. (385 aa)
AGP52893.1enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the enoyl-CoA hydratase/isomerase family. (275 aa)
AGP52945.1methylmalonyl-CoA mutase; MDM; functions in conversion of succinate to propionate; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (737 aa)
AGP52946.1methylmalonyl-CoA mutase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (590 aa)
AGP53081.1Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (355 aa)
AGP53329.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the thiolase-like superfamily. Thiolase family. (382 aa)
AGP53878.13-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (735 aa)
AGP53879.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the thiolase-like superfamily. Thiolase family. (404 aa)
AGP53999.1acetyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (568 aa)
AGP54004.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (272 aa)
AGP54010.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (137 aa)
AGP54031.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (272 aa)
AGP54066.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (300 aa)
AGP54067.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the thiolase-like superfamily. Thiolase family. (402 aa)
sucDsuccinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (298 aa)
sucCsuccinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (374 aa)
AGP54210.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (261 aa)
AGP54271.1Aminotransferase class III; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (450 aa)
AGP54327.1AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (565 aa)
AGP54685.14-aminobutyrate aminotransferase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (449 aa)
AGP54934.1Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (708 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (381 aa)
AGP54942.1methylmalonyl-CoA mutase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (532 aa)
AGP54957.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the thiolase-like superfamily. Thiolase family. (398 aa)
AGP54958.1methylmalonyl-CoA epimerase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (150 aa)
AGP55263.1acyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (632 aa)
AGP55726.1pimeloyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (749 aa)
acsAacetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (667 aa)
AGP57081.1acetyl-CoA carboxylase subunit alpha; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (670 aa)
AGP57084.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (384 aa)
AGP57138.1methylmalonyl-CoA mutase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (136 aa)
sucC-2succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (390 aa)
sucD-2succinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (294 aa)
AGP57187.1methylmalonyl-CoA mutase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (529 aa)
AGP57298.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the thiolase-like superfamily. Thiolase family. (406 aa)
AGP57661.1Biotin carboxyl carrier protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (730 aa)
AGP57736.1Methylmalonate-semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (498 aa)
AGP58214.1acetyl-CoA acetyltransferase; Catalyzes the thiolytic cleavage of beta-ketoadipyl-CoA to succinate and acetyl-CoA; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the thiolase-like superfamily. Thiolase family. (389 aa)
AGP58461.1Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (341 aa)
AGP58504.1Dihydrolipoamide dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (462 aa)
AGP59890.1Acetoacetate decarboxylase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (268 aa)
AGP60045.1enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (268 aa)
AGP60048.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (388 aa)
AGP60206.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the thiolase-like superfamily. Thiolase family. (396 aa)
AGP60212.1enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (282 aa)
AGP60215.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the thiolase-like superfamily. Thiolase family. (385 aa)
AGP60219.1enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (255 aa)
AGP60222.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the thiolase-like superfamily. Thiolase family. (356 aa)
AGP60306.13-hydroxyisobutyryl-CoA hydrolase; Catalyzes the formation of 3-hydroxy-2-methylpropanoate from 3-hydroxy-2-methylpropanoyl-CoA; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (358 aa)
AGP61043.1CoA-binding protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (691 aa)
AGP61192.1methylmalonyl-CoA carboxyltransferase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (529 aa)
AGP61193.1Biotin carboxyl carrier protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (590 aa)
AGP61263.1enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the enoyl-CoA hydratase/isomerase family. (254 aa)
AGP61411.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (207 aa)
AGP61467.1enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the enoyl-CoA hydratase/isomerase family. (254 aa)
Your Current Organism:
Streptomyces rapamycinicus
NCBI taxonomy Id: 1343740
Other names: S. rapamycinicus NRRL 5491, Streptomyces rapamycinicus NRRL 5491
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