STRINGSTRING
AGP51704.1 AGP51704.1 AGP51740.1 AGP51740.1 AGP51741.1 AGP51741.1 AGP52285.1 AGP52285.1 AGP52377.1 AGP52377.1 AGP52639.1 AGP52639.1 AGP52640.1 AGP52640.1 AGP52886.1 AGP52886.1 AGP52893.1 AGP52893.1 AGP52908.1 AGP52908.1 AGP52928.1 AGP52928.1 AGP52990.1 AGP52990.1 AGP53277.1 AGP53277.1 AGP53329.1 AGP53329.1 AGP53456.1 AGP53456.1 AGP53771.1 AGP53771.1 AGP53878.1 AGP53878.1 AGP53879.1 AGP53879.1 AGP53935.1 AGP53935.1 AGP54004.1 AGP54004.1 AGP54031.1 AGP54031.1 AGP54032.1 AGP54032.1 AGP54066.1 AGP54066.1 AGP54067.1 AGP54067.1 AGP54078.1 AGP54078.1 AGP54106.1 AGP54106.1 AGP54208.1 AGP54208.1 AGP54210.1 AGP54210.1 AGP54241.1 AGP54241.1 AGP54245.1 AGP54245.1 AGP54271.1 AGP54271.1 AGP54685.1 AGP54685.1 AGP54701.1 AGP54701.1 AGP54803.1 AGP54803.1 AGP54804.1 AGP54804.1 AGP54957.1 AGP54957.1 AGP54969.1 AGP54969.1 AGP55249.1 AGP55249.1 AGP55250.1 AGP55250.1 AGP55272.1 AGP55272.1 AGP55506.1 AGP55506.1 AGP55914.1 AGP55914.1 AGP55915.1 AGP55915.1 AGP56475.1 AGP56475.1 AGP56881.1 AGP56881.1 AGP57084.1 AGP57084.1 gabD2 gabD2 AGP57177.1 AGP57177.1 AGP57178.1 AGP57178.1 AGP57179.1 AGP57179.1 AGP57180.1 AGP57180.1 AGP57298.1 AGP57298.1 AGP57587.1 AGP57587.1 AGP57660.1 AGP57660.1 AGP57998.1 AGP57998.1 AGP57999.1 AGP57999.1 AGP58214.1 AGP58214.1 AGP58371.1 AGP58371.1 AGP59031.1 AGP59031.1 AGP59195.1 AGP59195.1 AGP59221.1 AGP59221.1 AGP59273.1 AGP59273.1 AGP60021.1 AGP60021.1 AGP60045.1 AGP60045.1 AGP60048.1 AGP60048.1 AGP60108.1 AGP60108.1 AGP60206.1 AGP60206.1 AGP60212.1 AGP60212.1 AGP60215.1 AGP60215.1 AGP60218.1 AGP60218.1 AGP60219.1 AGP60219.1 AGP60222.1 AGP60222.1 maiA maiA AGP60306.1 AGP60306.1 AGP60445.1 AGP60445.1 sdhA sdhA AGP60447.1 AGP60447.1 AGP60595.1 AGP60595.1 AGP60596.1 AGP60596.1 AGP61030.1 AGP61030.1 AGP61069.1 AGP61069.1 AGP61079.1 AGP61079.1 AGP61110.1 AGP61110.1 AGP61263.1 AGP61263.1 AGP61411.1 AGP61411.1 AGP61467.1 AGP61467.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AGP51704.1Hypothetical protein; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. (287 aa)
AGP51740.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the thiolase-like superfamily. Thiolase family. (387 aa)
AGP51741.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the enoyl-CoA hydratase/isomerase family. (249 aa)
AGP52285.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (391 aa)
AGP52377.1Succinate-semialdehyde dehdyrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the aldehyde dehydrogenase family. (492 aa)
AGP52639.1Succinate-semialdehyde dehdyrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the aldehyde dehydrogenase family. (490 aa)
AGP52640.14-aminobutyrate aminotransferase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (419 aa)
AGP52886.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the thiolase-like superfamily. Thiolase family. (385 aa)
AGP52893.1enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the enoyl-CoA hydratase/isomerase family. (275 aa)
AGP52908.1NADPH:quinone reductase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (446 aa)
AGP52928.13-hydroxybutyryl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (572 aa)
AGP52990.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (697 aa)
AGP53277.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (255 aa)
AGP53329.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the thiolase-like superfamily. Thiolase family. (382 aa)
AGP53456.1Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. (321 aa)
AGP53771.13-hydroxybutyryl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (285 aa)
AGP53878.13-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (735 aa)
AGP53879.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the thiolase-like superfamily. Thiolase family. (404 aa)
AGP53935.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the TPP enzyme family. (571 aa)
AGP54004.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (272 aa)
AGP54031.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (272 aa)
AGP54032.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (247 aa)
AGP54066.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (300 aa)
AGP54067.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the thiolase-like superfamily. Thiolase family. (402 aa)
AGP54078.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the TPP enzyme family. (540 aa)
AGP54106.1Acetolactate synthase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the TPP enzyme family. (571 aa)
AGP54208.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (285 aa)
AGP54210.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (261 aa)
AGP54241.13-hydroxybutyryl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (612 aa)
AGP54245.1NADPH:quinone reductase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (448 aa)
AGP54271.1Aminotransferase class III; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (450 aa)
AGP54685.14-aminobutyrate aminotransferase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (449 aa)
AGP54701.1Acetolactate synthase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the TPP enzyme family. (562 aa)
AGP54803.1Acetolactate synthase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (174 aa)
AGP54804.1Acetolactate synthase large subunit; catalyzes the formation of 2-acetolactate from pyruvate; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (617 aa)
AGP54957.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the thiolase-like superfamily. Thiolase family. (398 aa)
AGP54969.13-hydroxybutyryl-CoA dehydrogenase; Converts (S)-3-hydroxybutanoyl-CoA to 3-acetoacetyl-CoA; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (282 aa)
AGP55249.1Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (651 aa)
AGP55250.1Catalyzes the fumarate and succinate interconversion; fumarate reductase is used under anaerobic conditions with glucose or glycerol as carbon source; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (256 aa)
AGP55272.1Acetolactate synthase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the TPP enzyme family. (595 aa)
AGP55506.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (266 aa)
AGP55914.12-oxoglutarate ferredoxin oxidoreductase subunit alpha; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (650 aa)
AGP55915.12-oxoacid ferredoxin oxidoreductase subunit beta; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (360 aa)
AGP56475.13-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (505 aa)
AGP56881.1Glutamate decarboxylase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the group II decarboxylase family. (423 aa)
AGP57084.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (384 aa)
gabD2NADP-dependent semialdehyde dehydrogenase; part of alternative pathway from alpha-ketoglutarate to succinate; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (536 aa)
AGP57177.1Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (257 aa)
AGP57178.1Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (584 aa)
AGP57179.1Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (156 aa)
AGP57180.1Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (114 aa)
AGP57298.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the thiolase-like superfamily. Thiolase family. (406 aa)
AGP57587.1Decarboxylase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (313 aa)
AGP57660.1hydroxymethylglutaryl-CoA lyase; Catalyzes the formation of acetoacetate and acetyl-CoA from 3-hydroxy-3-methylglutaryl-CoA; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (310 aa)
AGP57998.13-oxoadipate:succinyl-CoA transferase subunit B; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (261 aa)
AGP57999.13-oxoadipate:succinyl-CoA transferase subunit A; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (278 aa)
AGP58214.1acetyl-CoA acetyltransferase; Catalyzes the thiolytic cleavage of beta-ketoadipyl-CoA to succinate and acetyl-CoA; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the thiolase-like superfamily. Thiolase family. (389 aa)
AGP58371.1Tartrate dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (358 aa)
AGP59031.1Succinate-semialdehyde dehdyrogenase; In Escherichia coli this enzyme appears to be an NAD+/NADP+-dependent succinate semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (469 aa)
AGP59195.1acetoacetyl-CoA synthetase; AcsA; in Sinorhizobium meliloti this enzyme is required for acetoacetate activation; similar to acetyl-CoA synthase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (662 aa)
AGP59221.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (476 aa)
AGP59273.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (455 aa)
AGP60021.13-hydroxybutyrate dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (268 aa)
AGP60045.1enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (268 aa)
AGP60048.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (388 aa)
AGP60108.1acetoacetyl-CoA synthetase; AcsA; in Sinorhizobium meliloti this enzyme is required for acetoacetate activation; similar to acetyl-CoA synthase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (672 aa)
AGP60206.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the thiolase-like superfamily. Thiolase family. (396 aa)
AGP60212.1enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (282 aa)
AGP60215.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the thiolase-like superfamily. Thiolase family. (385 aa)
AGP60218.1CoA-transferase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (288 aa)
AGP60219.1enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (255 aa)
AGP60222.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the thiolase-like superfamily. Thiolase family. (356 aa)
maiAHypothetical protein; Catalyzes cis-trans isomerization of the C2-C3 double bond in maleate to yield fumarate. (278 aa)
AGP60306.13-hydroxyisobutyryl-CoA hydrolase; Catalyzes the formation of 3-hydroxy-2-methylpropanoate from 3-hydroxy-2-methylpropanoyl-CoA; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (358 aa)
AGP60445.1Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (248 aa)
sdhAPart of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (655 aa)
AGP60447.1Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (240 aa)
AGP60595.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (217 aa)
AGP60596.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (251 aa)
AGP61030.13-hydroxybutyryl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (286 aa)
AGP61069.1Tartrate dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (360 aa)
AGP61079.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (170 aa)
AGP61110.1Pyruvate carboxyltransferase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (311 aa)
AGP61263.1enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the enoyl-CoA hydratase/isomerase family. (254 aa)
AGP61411.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (207 aa)
AGP61467.1enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the enoyl-CoA hydratase/isomerase family. (254 aa)
Your Current Organism:
Streptomyces rapamycinicus
NCBI taxonomy Id: 1343740
Other names: S. rapamycinicus NRRL 5491, Streptomyces rapamycinicus NRRL 5491
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