STRINGSTRING
AGP51761.1 AGP51761.1 AGP51843.1 AGP51843.1 AGP52062.1 AGP52062.1 AGP52285.1 AGP52285.1 AGP52319.1 AGP52319.1 AGP52821.1 AGP52821.1 AGP53291.1 AGP53291.1 AGP53645.1 AGP53645.1 AGP53715.1 AGP53715.1 AGP53935.1 AGP53935.1 AGP54078.1 AGP54078.1 AGP54106.1 AGP54106.1 AGP54130.1 AGP54130.1 AGP54231.1 AGP54231.1 AGP54270.1 AGP54270.1 AGP54272.1 AGP54272.1 AGP54701.1 AGP54701.1 coaD coaD AGP54789.1 AGP54789.1 ilvC ilvC AGP54803.1 AGP54803.1 AGP54804.1 AGP54804.1 AGP55272.1 AGP55272.1 acpS acpS coaA coaA AGP56003.1 AGP56003.1 ilvD ilvD AGP56875.1 AGP56875.1 panC panC coaX coaX AGP57246.1 AGP57246.1 AGP57577.1 AGP57577.1 AGP58225.1 AGP58225.1 panB panB coaE coaE AGP59282.1 AGP59282.1 AGP60261.1 AGP60261.1 AGP61079.1 AGP61079.1 AGP61346.1 AGP61346.1 AGP61398.1 AGP61398.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AGP51761.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (497 aa)
AGP51843.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the IlvD/Edd family. (564 aa)
AGP52062.12-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (296 aa)
AGP52285.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (391 aa)
AGP52319.1Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the aldehyde dehydrogenase family. (509 aa)
AGP52821.12-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (312 aa)
AGP53291.1Dihydroxy-acid dehydratase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the IlvD/Edd family. (551 aa)
AGP53645.1Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (402 aa)
AGP53715.1Class IV aminotransferase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (275 aa)
AGP53935.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the TPP enzyme family. (571 aa)
AGP54078.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the TPP enzyme family. (540 aa)
AGP54106.1Acetolactate synthase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the TPP enzyme family. (571 aa)
AGP54130.12-dehydropantoate 2-reductase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (332 aa)
AGP54231.14-phosphopantetheinyl transferase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the P-Pant transferase superfamily. (247 aa)
AGP54270.1Phenylhydantoinase; Catalyzes the hydrolytic cleavage of hydantoin with aromatic side chains at the 5'position; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (466 aa)
AGP54272.1Apolipoprotein acyltransferase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (280 aa)
AGP54701.1Acetolactate synthase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the TPP enzyme family. (562 aa)
coaDPhosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (159 aa)
AGP54789.1Catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (361 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (332 aa)
AGP54803.1Acetolactate synthase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (174 aa)
AGP54804.1Acetolactate synthase large subunit; catalyzes the formation of 2-acetolactate from pyruvate; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (617 aa)
AGP55272.1Acetolactate synthase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the TPP enzyme family. (595 aa)
acpS4'-phosphopantetheinyl transferase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. (122 aa)
coaAPantothenate kinase; Catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (336 aa)
AGP56003.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the IlvD/Edd family. (547 aa)
ilvDDihydroxy-acid dehydratase; Catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the IlvD/Edd family. (602 aa)
AGP56875.1Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the aldehyde dehydrogenase family. (485 aa)
panCPantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (308 aa)
coaXPantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (265 aa)
AGP57246.1Betaine-aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the aldehyde dehydrogenase family. (486 aa)
AGP57577.14-phosphopantetheinyl transferase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the P-Pant transferase superfamily. (282 aa)
AGP58225.1Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the aldehyde dehydrogenase family. (488 aa)
panB3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (286 aa)
coaEdephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (202 aa)
AGP59282.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the aldehyde dehydrogenase family. (512 aa)
AGP60261.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the aldehyde dehydrogenase family. (489 aa)
AGP61079.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (170 aa)
AGP61346.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (222 aa)
AGP61398.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the aldehyde dehydrogenase family. (524 aa)
Your Current Organism:
Streptomyces rapamycinicus
NCBI taxonomy Id: 1343740
Other names: S. rapamycinicus NRRL 5491, Streptomyces rapamycinicus NRRL 5491
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