(21 nodes) RHO GTPases Activate WASPs and WAVEs, and Actin filament depolymerization network (Ascoidea rubescens)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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Predicted Interactions

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Your Input:
	A0A1D2V919	Uncharacterized protein. (616 aa)
	A0A1D2VAY3	Uncharacterized protein. (1321 aa)
	A0A1D2VB51	Myosin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1245 aa)
	A0A1D2VBM9	WH1-domain-containing protein. (695 aa)
	A0A1D2VBZ4	WD40 repeat-like protein. (622 aa)
	A0A1D2VCH3	Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks; Belongs to the WD repeat ARPC1 family. (376 aa)
	A0A1D2VCT3	Adenylyl cyclase-associated protein; Belongs to the CAP family. (574 aa)
	A0A1D2VCX1	Essential component of the Arp2/3 complex; Belongs to the actin family. (440 aa)
	A0A1D2VDC7	Uncharacterized protein. (792 aa)
	A0A1D2VGX4	Uncharacterized protein. (927 aa)
	A0A1D2VH79	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (142 aa)
	A0A1D2VHE2	Uncharacterized protein. (1148 aa)
	A0A1D2VHS2	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (337 aa)
	A0A1D2VIR9	Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (153 aa)
	A0A1D2VK30	Glycoside hydrolase family 28 protein. (370 aa)
	A0A1D2VM19	Actin-2; Belongs to the actin family. (390 aa)
	A0A1D2VMP0	Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (176 aa)
	A0A1D2VPF9	Uncharacterized protein. (627 aa)
	A0A1D2VPQ8	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (347 aa)
	A0A1D2VQ39	ARP23 complex 20 kDa subunit. (168 aa)
	A0A1D2VS78	Actin depolymerizing protein. (383 aa)

Your Current Organism:

Ascoidea rubescens

NCBI taxonomy Id: 1344418
Other names: A. rubescens DSM 1968, Ascoidea rubescens DSM 1968

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A1D2V919	A0A1D2VAY3	Uncharacterized protein.	Uncharacterized protein.	0.811
A0A1D2V919	A0A1D2VB51	Uncharacterized protein.	Myosin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.833
A0A1D2V919	A0A1D2VBM9	Uncharacterized protein.	WH1-domain-containing protein.	0.985
A0A1D2V919	A0A1D2VCX1	Uncharacterized protein.	Essential component of the Arp2/3 complex; Belongs to the actin family.	0.611
A0A1D2V919	A0A1D2VDC7	Uncharacterized protein.	Uncharacterized protein.	0.422
A0A1D2V919	A0A1D2VGX4	Uncharacterized protein.	Uncharacterized protein.	0.739
A0A1D2V919	A0A1D2VHE2	Uncharacterized protein.	Uncharacterized protein.	0.693
A0A1D2V919	A0A1D2VHS2	Uncharacterized protein.	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.	0.726
A0A1D2V919	A0A1D2VK30	Uncharacterized protein.	Glycoside hydrolase family 28 protein.	0.921
A0A1D2V919	A0A1D2VM19	Uncharacterized protein.	Actin-2; Belongs to the actin family.	0.738
A0A1D2VAY3	A0A1D2V919	Uncharacterized protein.	Uncharacterized protein.	0.811
A0A1D2VAY3	A0A1D2VBM9	Uncharacterized protein.	WH1-domain-containing protein.	0.770
A0A1D2VAY3	A0A1D2VCH3	Uncharacterized protein.	Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks; Belongs to the WD repeat ARPC1 family.	0.942
A0A1D2VAY3	A0A1D2VCX1	Uncharacterized protein.	Essential component of the Arp2/3 complex; Belongs to the actin family.	0.948
A0A1D2VAY3	A0A1D2VGX4	Uncharacterized protein.	Uncharacterized protein.	0.696
A0A1D2VAY3	A0A1D2VHE2	Uncharacterized protein.	Uncharacterized protein.	0.779
A0A1D2VAY3	A0A1D2VHS2	Uncharacterized protein.	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.	0.948
A0A1D2VAY3	A0A1D2VIR9	Uncharacterized protein.	Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development.	0.961
A0A1D2VAY3	A0A1D2VK30	Uncharacterized protein.	Glycoside hydrolase family 28 protein.	0.719
A0A1D2VAY3	A0A1D2VM19	Uncharacterized protein.	Actin-2; Belongs to the actin family.	0.794