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NG55_12110 NG55_12110 argC argC NG55_01400 NG55_01400 NG55_02130 NG55_02130 NG55_02845 NG55_02845 NG55_02900 NG55_02900 NG55_03610 NG55_03610 NG55_05530 NG55_05530 NG55_05845 NG55_05845 argB argB NG55_06490 NG55_06490 NG55_06800 NG55_06800 NG55_07315 NG55_07315 NG55_07480 NG55_07480 NG55_08790 NG55_08790 ilvD ilvD NG55_09250 NG55_09250 NG55_09515 NG55_09515 NG55_10975 NG55_10975 leuA leuA NG55_11970 NG55_11970 argA argA NG55_18510 NG55_18510 NG55_18505 NG55_18505 ilvC ilvC NG55_18355 NG55_18355 NG55_18120 NG55_18120 ilvE ilvE NG55_17175 NG55_17175 NG55_17065 NG55_17065 NG55_16430 NG55_16430 gltA gltA asd asd leuB leuB leuD leuD leuC leuC argJ argJ NG55_13785 NG55_13785 NG55_12120 NG55_12120
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NG55_12110Converts isocitrate to alpha ketoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology. (418 aa)
argCN-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (349 aa)
NG55_01400Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (154 aa)
NG55_02130Bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; Catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aconitase/IPM isomerase family. (879 aa)
NG55_02845Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (476 aa)
NG55_02900GntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (250 aa)
NG55_03610Aspartate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartokinase family. (426 aa)
NG55_05530GntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (501 aa)
NG55_05845GNAT family acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (149 aa)
argBAcetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (299 aa)
NG55_06490FxsA cytoplasmic membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (186 aa)
NG55_06800Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (476 aa)
NG55_07315Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. (546 aa)
NG55_07480DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (502 aa)
NG55_08790Aspartate aminotransferase; Catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology. (411 aa)
ilvDDihydroxy-acid dehydratase; Catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. (609 aa)
NG55_09250GntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (475 aa)
NG55_09515Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (384 aa)
NG55_10975GntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (493 aa)
leuA2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (565 aa)
NG55_11970Diaminobutyrate--2-oxoglutarate aminotransferase; Catalyzes the reversible formation of diaminobutyrate and 2-oxoglutarate from glutamate and L-aspartic beta-semialdehyde; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (456 aa)
argAN-acetylglutamate synthase; Catalyzes the formation of N-acetyl-L-glutamate from L-glutamate and acetyl-CoA in arginine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the acetyltransferase family. ArgA subfamily. (451 aa)
NG55_18510Acetolactate synthase 3 catalytic subunit; Catalyzes the formation of 2-acetolactate from pyruvate, leucine sensitive; Derived by automated computational analysis using gene prediction method: Protein Homology. (574 aa)
NG55_18505Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (163 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (338 aa)
NG55_18355Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (918 aa)
NG55_18120Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (417 aa)
ilvEBranched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (308 aa)
NG55_17175Histone acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (161 aa)
NG55_17065TENA/THI-4 domain protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (248 aa)
NG55_16430GntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (465 aa)
gltAType II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family. (424 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (372 aa)
leuB3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (359 aa)
leuD3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (216 aa)
leuCIsopropylmalate isomerase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (472 aa)
argJOrnithine acetyltransferase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (406 aa)
NG55_13785Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (413 aa)
NG55_12120Isocitrate dehydrogenase; NADP-specific, catalyzes the formation of 2-oxoglutarate from isocitrate or oxalosuccinate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the monomeric-type IDH family. (743 aa)
Your Current Organism:
Acinetobacter gyllenbergii
NCBI taxonomy Id: 134534
Other names: A. gyllenbergii, Acinetobacter gyllenbergii Nemec et al. 2009, Acinetobacter sp. NIPH 2021, Acinetobacter sp. NIPH 2022, Acinetobacter sp. NIPH 2150, Acinetobacter sp. NIPH 230, Acinetobacter sp. NIPH 2353, Acinetobacter sp. NIPH 802, Acinetobacter sp. NIPH 822, Acinetobacter sp. NIPH 975, Acinetobacter sp. phenon 3, CCM 7267, CCUG 51248, DSM 22705, NIPH 2150, RUH 422
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