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tsaD tsaD OI25_3679 OI25_3679 OI25_3678 OI25_3678 yeaZ yeaZ hscA hscA ppx ppx OI25_2184 OI25_2184 xylB xylB OI25_2164 OI25_2164 glpK glpK anmK anmK ftsA ftsA OI25_1880 OI25_1880 OI25_1597 OI25_1597 gspL gspL OI25_1369 OI25_1369 coaX coaX OI25_6898 OI25_6898 glk glk ackA ackA OI25_7074 OI25_7074 dnaK dnaK OI25_4673 OI25_4673 OI25_4676 OI25_4676 OI25_4886 OI25_4886 OI25_5522 OI25_5522 OI25_5547 OI25_5547 xylB-2 xylB-2 OI25_6221 OI25_6221 OI25_6645 OI25_6645
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
tsaDtRNA threonylcarbamoyl adenosine modification protein TsaD; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. (342 aa)
OI25_3679DNA-K related family protein; [O] COG0443 Molecular chaperone. (961 aa)
OI25_3678Hsp70 family protein; [O] COG0443 Molecular chaperone; Belongs to the heat shock protein 70 family. (616 aa)
yeaZT6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ; [O] COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone. (270 aa)
hscAFe-S protein assembly chaperone HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. (623 aa)
ppxppx/GppA phosphatase family protein; [FP] COG0248 Exopolyphosphatase. (503 aa)
OI25_2184Hypothetical protein; FGGY family of carbohydrate kinase, N-terminal domain protein; [G] COG1070 Sugar (pentulose and hexulose) kinases; Belongs to the FGGY kinase family. (514 aa)
xylBxylB: xylulokinase; [G] COG1070 Sugar (pentulose and hexulose) kinases. (493 aa)
OI25_2164Hypothetical protein; FGGY family of carbohydrate kinase, N-terminal domain protein; [G] COG1070 Sugar (pentulose and hexulose) kinases. (483 aa)
glpKGlycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. (499 aa)
anmKHypothetical protein; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. (376 aa)
ftsACell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. (410 aa)
OI25_1880Hsp70 family protein; [O] COG0443 Molecular chaperone. (416 aa)
OI25_1597[G] COG2971 Predicted N-acetylglucosamine kinase. (293 aa)
gspLtypeII_sec_gspL: type II secretion system protein L; [U] COG3297 Type II secretory pathway, component PulL. (473 aa)
OI25_1369mreB: cell shape determining, MreB/Mrl family protein; [D] COG1077 Actin-like ATPase involved in cell morphogenesis. (347 aa)
coaXPantothenate kinase, type III family protein; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (271 aa)
OI25_6898mreB: cell shape determining, MreB/Mrl family protein; [D] COG1077 Actin-like ATPase involved in cell morphogenesis. (350 aa)
glkGlk: glucokinase; [G] COG0837 Glucokinase; Belongs to the bacterial glucokinase family. (638 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (389 aa)
OI25_7074mreB: cell shape determining, MreB/Mrl family protein; [D] COG1077 Actin-like ATPase involved in cell morphogenesis. (347 aa)
dnaKChaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. (650 aa)
OI25_4673ROK family protein; [KG] COG1940 Transcriptional regulator/sugar kinase. (337 aa)
OI25_4676Sugar-specific transcriptional regulator TrmB family protein; [KG] COG1940 Transcriptional regulator/sugar kinase. (403 aa)
OI25_4886Carbamoyltransferase family protein; [O] COG2192 Predicted carbamoyl transferase, NodU family. (581 aa)
OI25_5522Carbohydrate kinase, FGGY family; [O] COG0443 Molecular chaperone; Belongs to the heat shock protein 70 family. (569 aa)
OI25_5547ROK family protein; [KG] COG1940 Transcriptional regulator/sugar kinase. (266 aa)
xylB-2xylB: xylulokinase; [G] COG1070 Sugar (pentulose and hexulose) kinases. (485 aa)
OI25_6221Hypothetical protein; FGGY family of carbohydrate kinase, N-terminal domain protein; [C] COG0554 Glycerol kinase; Belongs to the FGGY kinase family. (511 aa)
OI25_6645marR family protein; [KG] COG1940 Transcriptional regulator/sugar kinase. (408 aa)
Your Current Organism:
Paraburkholderia fungorum
NCBI taxonomy Id: 134537
Other names: ATCC BAA-463, Burkholderia fungorum, Burkholderia fungorum Coenye et al. 2001, Burkholderia sp. LMG 16225, Burkholderia sp. LMG 16307, Burkholderia sp. LMG16225, Burkholderia sp. LMG16307, CCUG 31961, CIP 107096, DSM 17061, JCM 21562, LMG 16225, LMG:16225, NBRC 102489, P. fungorum, Paraburkholderia fungorum (Coenye et al. 2001) Sawana et al. 2015, strain Croize P763-2
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