STRINGSTRING
prs prs plsX plsX APD31009.1 APD31009.1 APD31026.1 APD31026.1 APD31077.1 APD31077.1 ackA ackA APD31120.1 APD31120.1 APD31132.1 APD31132.1 APD31133.1 APD31133.1 APD31134.1 APD31134.1 APD31167.1 APD31167.1 cutC cutC cutD cutD APD31171.1 APD31171.1 APD31176.1 APD31176.1 nifJ nifJ APD31241.1 APD31241.1 APD31296.1 APD31296.1 APD31297.1 APD31297.1 APD31410.1 APD31410.1 APD31486.1 APD31486.1 APD32838.1 APD32838.1 APD31560.1 APD31560.1 APD31561.1 APD31561.1 APD31562.1 APD31562.1 APD31563.1 APD31563.1 APD31564.1 APD31564.1 APD31585.1 APD31585.1 dltA dltA dltB dltB dltC dltC dltD dltD APD31638.1 APD31638.1 APD31639.1 APD31639.1 APD31640.1 APD31640.1 lpdA lpdA APD31642.1 APD31642.1 APD31671.1 APD31671.1 pepV pepV plsY plsY APD31778.1 APD31778.1 APD31791.1 APD31791.1 APD31792.1 APD31792.1 ldh ldh APD31861.1 APD31861.1 pta pta APD31967.1 APD31967.1 APD31968.1 APD31968.1 APD31969.1 APD31969.1 pflA pflA APD32291.1 APD32291.1 APD32408.1 APD32408.1 accA accA accD accD accC accC fabZ fabZ APD32444.1 APD32444.1 fabF fabF fabG fabG fabD fabD fabK fabK acpP acpP fabH fabH APD32451.1 APD32451.1 APD32452.1 APD32452.1 pflB pflB gpsA gpsA APD32804.1 APD32804.1 APD32805.1 APD32805.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (321 aa)
plsXPhosphate acyltransferase; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (331 aa)
APD31009.1Acyl carrier protein; Carries the fatty acid chain in fatty acid biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (78 aa)
APD31026.1Bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. (882 aa)
APD31077.1Alcohol dehydrogenase AdhP; Derived by automated computational analysis using gene prediction method: Protein Homology. (339 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (398 aa)
APD31120.1Deoxynucleoside kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (214 aa)
APD31132.1Pyruvate formate lyase-activating protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (258 aa)
APD31133.1DeoR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (247 aa)
APD31134.1Glycyl radical enzyme; Derived by automated computational analysis using gene prediction method: Protein Homology. (804 aa)
APD31167.1Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (451 aa)
cutCCholine trimethylamine-lyase; Glycine radical enzyme that catalyzes the cleavage of a C-N bond in choline, producing trimethylamine (TMA) and acetaldehyde. Belongs to the glycyl radical enzyme (GRE) family. CutC subfamily. (848 aa)
cutDCholine TMA-lyase-activating enzyme; Catalyzes activation of the choline trimethylamine-lyase CutC under anaerobic conditions by generation of an organic free radical on a glycine residue, via an homolytic cleavage of S-adenosyl-L-methionine (SAM). (318 aa)
APD31171.1Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (376 aa)
APD31176.1Acetaldehyde dehydrogenase (acetylating); Derived by automated computational analysis using gene prediction method: Protein Homology. (553 aa)
nifJPyruvate:ferredoxin (flavodoxin) oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1211 aa)
APD31241.1MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (389 aa)
APD31296.1Phosphoenolpyruvate carboxykinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (546 aa)
APD31297.1Alpha/beta hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (240 aa)
APD31410.1GNAT family N-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (146 aa)
APD31486.11-acyl-sn-glycerol-3-phosphate acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (245 aa)
APD32838.1NADP-dependent glyceraldehyde-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (475 aa)
APD31560.1Long-chain fatty acid--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (506 aa)
APD31561.1glutaryl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (401 aa)
APD31562.14-hydroxybutyrate CoA-transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (438 aa)
APD31563.13-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (752 aa)
APD31564.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (397 aa)
APD31585.1D-alanyl-lipoteichoic acid biosynthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (47 aa)
dltAD-alanine--poly(phosphoribitol) ligase subunit 1; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Belongs to [...] (512 aa)
dltBD-alanyl-lipoteichoic acid biosynthesis protein DltB; Could be involved in the transport of activated D-alanine through the membrane. (419 aa)
dltCD-alanine--poly(phosphoribitol) ligase subunit 2; Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC- carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. (81 aa)
dltDD-alanyl-lipoteichoic acid biosynthesis protein DltD; Derived by automated computational analysis using gene prediction method: Protein Homology. (419 aa)
APD31638.1Pyruvate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (322 aa)
APD31639.1Alpha-ketoacid dehydrogenase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. (332 aa)
APD31640.1Iron ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (471 aa)
lpdADihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (584 aa)
APD31642.1Lipoate--protein ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (329 aa)
APD31671.1Nitroreductase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (200 aa)
pepVDipeptidase PepV; Derived by automated computational analysis using gene prediction method: Protein Homology. (467 aa)
plsYGlycerol-3-phosphate acyltransferase; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. (211 aa)
APD31778.1Protein--protein lipoyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (274 aa)
APD31791.1PTS fructose transporter subunit IIA; Derived by automated computational analysis using gene prediction method: Protein Homology. (428 aa)
APD31792.1Acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (279 aa)
ldhL-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (327 aa)
APD31861.1NAD(P)-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (252 aa)
ptaPhosphate acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (330 aa)
APD31967.1Glutathione-disulfide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (451 aa)
APD31968.1L-lactate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LDH/MDH superfamily. (305 aa)
APD31969.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0342 family. (113 aa)
pflAPyruvate formate-lyase 1-activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family. (263 aa)
APD32291.1Phosphatase PAP2 family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (216 aa)
APD32408.1Esterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (336 aa)
accAacetyl-CoA carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (256 aa)
accDacetyl-CoA carboxylase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (288 aa)
accCacetyl-CoA carboxylase biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (454 aa)
fabZ3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (141 aa)
APD32444.1acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (146 aa)
fabFBeta-ketoacyl-[acyl-carrier-protein] synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (410 aa)
fabG3-oxoacyl-[acyl-carrier-protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (244 aa)
fabD[acyl-carrier-protein] S-malonyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (309 aa)
fabK2-nitropropane dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (321 aa)
acpPAcyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. (74 aa)
fabH3-oxoacyl-ACP synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (324 aa)
APD32451.1MarR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (144 aa)
APD32452.1enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (263 aa)
pflBFormate C-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (775 aa)
gpsAGlycerol-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (338 aa)
APD32804.1Peptidase M16; Derived by automated computational analysis using gene prediction method: Protein Homology. (427 aa)
APD32805.1Peptidase M16; Derived by automated computational analysis using gene prediction method: Protein Homology. (417 aa)
Your Current Organism:
Streptococcus iniae
NCBI taxonomy Id: 1346
Other names: ATCC 29178, CCUG 27303, CIP 102508, DSM 20576, LMG 14520, LMG:14520, S. iniae, Streptococcus shiloi, strain PW
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