STRINGSTRING
APD30987.1 APD30987.1 APD31002.1 APD31002.1 APD31003.1 APD31003.1 APD31004.1 APD31004.1 APD31094.1 APD31094.1 APD31097.1 APD31097.1 APD31105.1 APD31105.1 APD32835.1 APD32835.1 APD31432.1 APD31432.1 typA typA APD31434.1 APD31434.1 murD murD murG murG divIB divIB ftsA ftsA ftsZ ftsZ APD31440.1 APD31440.1 sepF sepF APD31442.1 APD31442.1 APD31443.1 APD31443.1 APD31444.1 APD31444.1 APD31471.1 APD31471.1 ddl ddl murF murF prsA prsA murA murA murB murB APD31973.1 APD31973.1 ezrA ezrA APD32047.1 APD32047.1 APD32072.1 APD32072.1 ftsE ftsE queG queG fbp fbp APD32076.1 APD32076.1 APD32089.1 APD32089.1 APD32274.1 APD32274.1 murE murE APD32302.1 APD32302.1 murC murC gpsB gpsB APD32373.1 APD32373.1 recU recU APD32375.1 APD32375.1 mraY mraY APD32386.1 APD32386.1 APD32491.1 APD32491.1 acpS acpS APD32678.1 APD32678.1 APD32718.1 APD32718.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
APD30987.1Septum formation initiation protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (123 aa)
APD31002.1Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape. (271 aa)
APD31003.1Rod shape-determining protein MreD; Derived by automated computational analysis using gene prediction method: Protein Homology. (165 aa)
APD31004.1CHAP domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (404 aa)
APD31094.1Transglycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (768 aa)
APD31097.1Dipicolinate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (121 aa)
APD31105.1SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (318 aa)
APD32835.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (80 aa)
APD31432.1NADH dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (128 aa)
typAGTP-binding protein TypA; Derived by automated computational analysis using gene prediction method: Protein Homology. (613 aa)
APD31434.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (79 aa)
murDUDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (452 aa)
murGUndecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (359 aa)
divIBCell division protein; Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex; Belongs to the FtsQ/DivIB family. DivIB subfamily. (397 aa)
ftsACell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. (454 aa)
ftsZCell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (438 aa)
APD31440.1YggS family pyridoxal phosphate enzyme; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. (223 aa)
sepFCell division protein SepF; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA. (204 aa)
APD31442.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (85 aa)
APD31443.1RNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (263 aa)
APD31444.1Cell division protein DivIVA; Derived by automated computational analysis using gene prediction method: Protein Homology. (253 aa)
APD31471.1Penicillin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (694 aa)
ddlD-alanine--D-alanine ligase A; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (348 aa)
murFUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (459 aa)
prsAFoldase PrsA; Plays a major role in protein secretion by helping the post- translocational extracellular folding of several secreted proteins. (313 aa)
murAUDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (419 aa)
murBUDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (299 aa)
APD31973.1Alkaline phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (724 aa)
ezrASeptation ring formation regulator EzrA; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family. (574 aa)
APD32047.1Rod shape-determining protein RodA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SEDS family. (404 aa)
APD32072.1Cell division protein FtsX; Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation. Belongs to the ABC-4 integral membrane protein family. FtsX subfamily. (309 aa)
ftsECell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division. (230 aa)
queGtRNA epoxyqueuosine(34) reductase QueG; Derived by automated computational analysis using gene prediction method: Protein Homology. (372 aa)
fbpFructose-1,6-bisphosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (639 aa)
APD32076.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (124 aa)
APD32089.1Cell division protein FtsW; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SEDS family. (426 aa)
APD32274.1Polysaccharide biosynthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (550 aa)
murEUDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of L-lysine to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan; Belongs to the MurCDEF family. MurE subfamily. (481 aa)
APD32302.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (79 aa)
murCUDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (443 aa)
gpsBCell division protein GpsB; Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation. (107 aa)
APD32373.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0398 family. (172 aa)
recUHolliday junction resolvase RecU; Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation; Belongs to the RecU family. (200 aa)
APD32375.1Penicillin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (735 aa)
mraYphospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (335 aa)
APD32386.1Penicillin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (750 aa)
APD32491.1Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (368 aa)
acpSholo-ACP synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. (117 aa)
APD32678.1Cell wall protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (929 aa)
APD32718.1Penicillin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (772 aa)
Your Current Organism:
Streptococcus iniae
NCBI taxonomy Id: 1346
Other names: ATCC 29178, CCUG 27303, CIP 102508, DSM 20576, LMG 14520, LMG:14520, S. iniae, Streptococcus shiloi, strain PW
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