STRINGSTRING
dnaA dnaA ychF ychF mfd mfd tilS tilS ftsH ftsH prs prs ruvB ruvB adk adk cydD cydD cydC cydC APD31089.1 APD31089.1 APD31091.1 APD31091.1 tyrS tyrS APD31098.1 APD31098.1 ackA ackA APD31119.1 APD31119.1 APD31120.1 APD31120.1 APD31158.1 APD31158.1 APD31170.1 APD31170.1 APD31172.1 APD31172.1 APD31173.1 APD31173.1 APD31185.1 APD31185.1 APD31188.1 APD31188.1 APD31194.1 APD31194.1 BMF34_01440 BMF34_01440 APD31203.1 APD31203.1 APD31217.1 APD31217.1 APD31222.1 APD31222.1 galK galK proS proS cysS cysS APD31275.1 APD31275.1 citC citC citG citG APD31296.1 APD31296.1 APD31301.1 APD31301.1 APD31304.1 APD31304.1 pyrG pyrG APD31313.1 APD31313.1 APD31324.1 APD31324.1 sufC sufC APD31340.1 APD31340.1 APD31341.1 APD31341.1 secA2 secA2 APD31364.1 APD31364.1 APD31378.1 APD31378.1 APD31385.1 APD31385.1 valS valS APD31387.1 APD31387.1 APD31396.1 APD31396.1 APD31402.1 APD31402.1 asnA asnA coaD coaD APD31419.1 APD31419.1 rbsK rbsK rbsA rbsA APD31429.1 APD31429.1 APD31430.1 APD31430.1 murD murD ileS ileS APD31448.1 APD31448.1 glnQ glnQ recN recN cadA cadA ddl ddl murF murF cshA cshA alaS alaS APD31512.1 APD31512.1 APD31517.1 APD31517.1 udk udk dnaX dnaX birA birA metK metK aroK aroK APD31555.1 APD31555.1 APD31567.1 APD31567.1 APD31568.1 APD31568.1 APD31575.1 APD31575.1 APD31576.1 APD31576.1 APD31581.1 APD31581.1 APD31582.1 APD31582.1 uvrB uvrB dltA dltA miaA miaA APD31633.1 APD31633.1 APD31636.1 APD31636.1 APD31642.1 APD31642.1 APD31644.1 APD31644.1 dacA dacA APD31658.1 APD31658.1 epsD epsD parE parE parC parC APD31714.1 APD31714.1 APD31715.1 APD31715.1 pfkA pfkA pyk pyk APD31728.1 APD31728.1 pcrA pcrA APD31742.1 APD31742.1 APD31750.1 APD31750.1 pstB pstB pstB-2 pstB-2 coaA coaA APD31769.1 APD31769.1 fhs fhs APD31782.1 APD31782.1 APD31784.1 APD31784.1 APD31788.1 APD31788.1 APD31805.1 APD31805.1 APD31806.1 APD31806.1 APD31811.1 APD31811.1 APD31818.1 APD31818.1 guaA guaA gyrA gyrA tdk tdk APD31858.1 APD31858.1 nadK nadK prs-2 prs-2 potA potA folK folK APD31898.1 APD31898.1 thrB thrB clpX clpX APD31918.1 APD31918.1 mvaD mvaD mvk mvk APD31921.1 APD31921.1 APD31922.1 APD31922.1 APD31925.1 APD31925.1 APD31926.1 APD31926.1 APD31928.1 APD31928.1 cca cca pfkB pfkB APD31948.1 APD31948.1 thiI thiI cmk cmk APD31992.1 APD31992.1 APD31997.1 APD31997.1 addA addA rexB rexB APD32005.1 APD32005.1 pheT pheT pheS pheS atpC atpC atpD atpD atpG atpG atpA atpA glgC glgC APD32026.1 APD32026.1 sagG sagG gyrB gyrB APD32066.1 APD32066.1 asnS asnS dinG dinG APD32072.1 APD32072.1 ftsE ftsE APD32079.1 APD32079.1 APD32093.1 APD32093.1 lysS lysS APD32106.1 APD32106.1 fhs-2 fhs-2 hprK hprK pstB-3 pstB-3 APD32152.1 APD32152.1 smc smc APD32161.1 APD32161.1 APD32852.1 APD32852.1 APD32177.1 APD32177.1 thrS thrS coaE coaE APD32209.1 APD32209.1 APD32212.1 APD32212.1 pyrH pyrH APD32224.1 APD32224.1 mtsB mtsB metG metG tmk tmk APD32266.1 APD32266.1 APD32267.1 APD32267.1 murE murE APD32278.1 APD32278.1 APD32289.1 APD32289.1 murC murC APD32317.1 APD32317.1 APD32319.1 APD32319.1 nrdR nrdR metN metN tmcAL tmcAL nadD nadD APD32352.1 APD32352.1 APD32359.1 APD32359.1 pknB pknB priA priA gmk gmk nadE nadE APD32382.1 APD32382.1 cshB cshB proB proB APD32391.1 APD32391.1 glpK glpK glyS glyS glyQ glyQ APD32411.1 APD32411.1 APD32424.1 APD32424.1 APD32425.1 APD32425.1 serS serS accA accA accD accD accC accC dnaJ dnaJ dnaK dnaK gatB gatB gatA gatA gatC gatC APD32467.1 APD32467.1 APD32468.1 APD32468.1 recG recG APD32482.1 APD32482.1 APD32485.1 APD32485.1 APD32486.1 APD32486.1 APD32487.1 APD32487.1 secA secA uvrA uvrA mutS2 mutS2 recD2 recD2 essC essC APD32564.1 APD32564.1 APD32569.1 APD32569.1 APD32571.1 APD32571.1 APD32586.1 APD32586.1 APD32587.1 APD32587.1 pgk pgk APD32600.1 APD32600.1 APD32604.1 APD32604.1 APD32638.1 APD32638.1 argG argG gltX gltX radA radA APD32665.1 APD32665.1 APD32666.1 APD32666.1 APD32670.1 APD32670.1 APD32691.1 APD32691.1 APD32692.1 APD32692.1 leuS leuS groL groL groS groS APD32728.1 APD32728.1 APD32750.1 APD32750.1 recA recA ruvA ruvA mutL mutL mutS mutS argS argS aspS aspS hisS hisS APD32790.1 APD32790.1 mnmA mnmA ecfA ecfA ecfA-2 ecfA-2 recF recF trpS trpS APD32812.1 APD32812.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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dnaAChromosomal replication initiation protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. (451 aa)
ychFRedox-regulated ATPase YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. (372 aa)
mfdTranscription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. (1166 aa)
tilStRNA lysidine(34) synthetase TilS; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. (395 aa)
ftsHCell division protein FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (655 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (321 aa)
ruvBHolliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (325 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (212 aa)
cydDThiol reductant ABC exporter subunit CydD; Derived by automated computational analysis using gene prediction method: Protein Homology. (572 aa)
cydCThiol reductant ABC exporter subunit CydC; Derived by automated computational analysis using gene prediction method: Protein Homology. (581 aa)
APD31089.14-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol; Belongs to the GHMP kinase family. IspE subfamily. (283 aa)
APD31091.1Zinc ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (232 aa)
tyrStyrosine--tRNA ligase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. (418 aa)
APD31098.1Competence protein CglA; Derived by automated computational analysis using gene prediction method: Protein Homology. (313 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (398 aa)
APD31119.1ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (267 aa)
APD31120.1Deoxynucleoside kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (214 aa)
APD31158.1Multidrug ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (291 aa)
APD31170.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (148 aa)
APD31172.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (212 aa)
APD31173.1Ethanolamine utilization protein EutJ; Derived by automated computational analysis using gene prediction method: Protein Homology. (279 aa)
APD31185.1Hemin ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (225 aa)
APD31188.1Phosphoribulokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (198 aa)
APD31194.1DNA topology modulation protein FlaR; Derived by automated computational analysis using gene prediction method: Protein Homology. (168 aa)
BMF34_01440IS256 family transposase; Internal stop; Derived by automated computational analysis using gene prediction method: Protein Homology. (232 aa)
APD31203.1Recombinase RarA; Derived by automated computational analysis using gene prediction method: Protein Homology. (423 aa)
APD31217.1GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (739 aa)
APD31222.1Sugar ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily. (377 aa)
galKGalactokinase; Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily. (387 aa)
proSproline--tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacy [...] (618 aa)
cysScysteine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. (447 aa)
APD31275.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (544 aa)
citC[citrate (pro-3S)-lyase] ligase; Acetylation of prosthetic group (2-(5''-phosphoribosyl)-3'- dephosphocoenzyme-A) of the gamma subunit of citrate lyase. (348 aa)
citGtriphosphoribosyl-dephospho-CoA synthase CitG; Derived by automated computational analysis using gene prediction method: Protein Homology. (295 aa)
APD31296.1Phosphoenolpyruvate carboxykinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (546 aa)
APD31301.1Heme ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (566 aa)
APD31304.1Aspartate kinase; Catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; lysine and threonine sensitive; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartokinase family. (450 aa)
pyrGCTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (535 aa)
APD31313.1Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (583 aa)
APD31324.1ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (246 aa)
sufCFe-S cluster assembly ATPase SufC; Derived by automated computational analysis using gene prediction method: Protein Homology. (256 aa)
APD31340.1Oligopeptide transport ATP-binding protein AmiE; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily. (356 aa)
APD31341.1Peptide ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily. (307 aa)
secA2Accessory Sec system translocase SecA2; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. (792 aa)
APD31364.1Multidrug ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (211 aa)
APD31378.1Sodium ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (297 aa)
APD31385.1Shikimate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (187 aa)
valSvaline--tRNA ligase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (883 aa)
APD31387.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (605 aa)
APD31396.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (86 aa)
APD31402.1ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily. (359 aa)
asnAAspartate--ammonia ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (330 aa)
coaDPantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (163 aa)
APD31419.1Peptidase S16; Derived by automated computational analysis using gene prediction method: Protein Homology. (345 aa)
rbsKRibokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (303 aa)
rbsAD-xylose ABC transporter ATP-binding protein; Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family. (492 aa)
APD31429.1Multidrug ABC transporter permease/ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (580 aa)
APD31430.1Multidrug ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (584 aa)
murDUDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (452 aa)
ileSisoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). (930 aa)
APD31448.1ATP-dependent Clp protease ATP-binding subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ClpA/ClpB family. (751 aa)
glnQSimilar to ATP-binding component of ABC transporters; Derived by automated computational analysis using gene prediction method: Protein Homology. (244 aa)
recNDNA repair protein RecN; May be involved in recombinational repair of damaged DNA. (552 aa)
cadACadmium-translocating P-type ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (617 aa)
ddlD-alanine--D-alanine ligase A; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (348 aa)
murFUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (459 aa)
cshAATP-dependent RNA helicase; DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA-dependent ATPase activity; Belongs to the DEAD box helicase family. CshA subfamily. (543 aa)
alaSalanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (872 aa)
APD31512.1Ribonucleotide-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (719 aa)
APD31517.1RNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (362 aa)
udkUridine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (208 aa)
dnaXDNA polymerase III subunit gamma/tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (557 aa)
birAbiotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. (311 aa)
metKMethionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (395 aa)
aroKShikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (172 aa)
APD31555.1Peptide ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (209 aa)
APD31567.1Methionine ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (218 aa)
APD31568.1Iron export ABC transporter permease subunit FetB; Derived by automated computational analysis using gene prediction method: Protein Homology. (257 aa)
APD31575.1Sugar ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (573 aa)
APD31576.1Multidrug ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (576 aa)
APD31581.1Multidrug ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (503 aa)
APD31582.1Peptide ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (246 aa)
uvrBExcinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] (663 aa)
dltAD-alanine--poly(phosphoribitol) ligase subunit 1; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Belongs to [...] (512 aa)
miaAtRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (294 aa)
APD31633.1Phosphonate ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (252 aa)
APD31636.1Multidrug ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (634 aa)
APD31642.1Lipoate--protein ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (329 aa)
APD31644.1UDP-N-acetylmuramyl peptide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (447 aa)
dacATIGR00159 family protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. (281 aa)
APD31658.1Nucleoside-diphosphate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (140 aa)
epsDTyrosine protein kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (239 aa)
parEDNA topoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 2 subfamily. (649 aa)
parCDNA topoisomerase IV subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 2 subfamily. (807 aa)
APD31714.1ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (265 aa)
APD31715.1ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (232 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (337 aa)
pykPyruvate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pyruvate kinase family. (500 aa)
APD31728.1Amino acid ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (209 aa)
pcrAATP-dependent DNA helicase PcrA; Derived by automated computational analysis using gene prediction method: Protein Homology. (766 aa)
APD31742.1Macrolide ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (233 aa)
APD31750.1Riboflavin biosynthesis protein RibF; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribF family. (310 aa)
pstBPhosphate ABC transporter ATP-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family. (267 aa)
pstB-2Phosphate ABC transporter ATP-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family. (252 aa)
coaAType I pantothenate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (306 aa)
APD31769.1Heme ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (510 aa)
fhsFormate--tetrahydrofolate ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the formate--tetrahydrofolate ligase family. (556 aa)
APD31782.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (112 aa)
APD31784.1Heme ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (514 aa)
APD31788.1Diacylglycerol kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (300 aa)
APD31805.1Bacteriocin ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (250 aa)
APD31806.1ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (651 aa)
APD31811.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (102 aa)
APD31818.1Cupin; Derived by automated computational analysis using gene prediction method: Protein Homology. (140 aa)
guaAGlutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. (520 aa)
gyrADNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (825 aa)
tdkThymidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (192 aa)
APD31858.1Glycine/betaine ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (242 aa)
nadKNAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (278 aa)
prs-2Ribose-phosphate diphosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (323 aa)
potASpermidine/putrescine ABC transporter ATP-binding protein; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family. (384 aa)
folK2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (163 aa)
APD31898.1Dihydrofolate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the folylpolyglutamate synthase family. (419 aa)
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (286 aa)
clpXATP-dependent protease ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. (409 aa)
APD31918.1Phosphomevalonate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (339 aa)
mvaDDiphosphomevalonate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (314 aa)
mvkMevalonate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (294 aa)
APD31921.1ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (580 aa)
APD31922.1ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (573 aa)
APD31925.1Multidrug ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (588 aa)
APD31926.1Multidrug ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (580 aa)
APD31928.1Antibiotic ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (628 aa)
ccaCCA tRNA nucleotidyltransferase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. (402 aa)
pfkB1-phosphofructokinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the carbohydrate kinase PfkB family. LacC subfamily. (303 aa)
APD31948.1Macrolide ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (237 aa)
thiItRNA 4-thiouridine(8) synthase ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (404 aa)
cmkCytidylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (226 aa)
APD31992.1Phosphate/phosphonate ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (388 aa)
APD31997.1Aromatic ring hydroxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (112 aa)
addAHelicase-exonuclease AddAB subunit AddA; ATP-dependent DNA helicase. (1215 aa)
rexBATP-dependent nuclease subunit B; The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' -> 3' nuclease activity; Belongs to the helicase family. AddB/RexB type 2 subfamily. (1078 aa)
APD32005.1Hemin ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (223 aa)
pheTphenylalanine--tRNA ligase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. (801 aa)
pheSphenylalanine--tRNA ligase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. (347 aa)
atpCF0F1 ATP synthase subunit epsilon; Produces ATP from ADP in the presence of a proton gradient across the membrane. (138 aa)
atpDF0F1 ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. (468 aa)
atpGF0F1 ATP synthase subunit gamma; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (291 aa)
atpAF0F1 ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. (501 aa)
glgCGlucose-1-phosphate adenylyltransferase subunit GlgD; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (379 aa)
APD32026.1Diacylglycerol kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (343 aa)
sagGABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (307 aa)
gyrBDNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (650 aa)
APD32066.1RNase adaptor protein RapZ; Displays ATPase and GTPase activities. (297 aa)
asnSasparagine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (448 aa)
dinGBifunctional DnaQ family exonuclease/ATP-dependent helicase; 3'-5' exonuclease. (820 aa)
APD32072.1Cell division protein FtsX; Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation. Belongs to the ABC-4 integral membrane protein family. FtsX subfamily. (309 aa)
ftsECell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division. (230 aa)
APD32079.1ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (894 aa)
APD32093.1ECF transporter S component; Derived by automated computational analysis using gene prediction method: Protein Homology. (167 aa)
lysSlysine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family. (496 aa)
APD32106.1Dihydrofolate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the folylpolyglutamate synthase family. (425 aa)
fhs-2Formate--tetrahydrofolate ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the formate--tetrahydrofolate ligase family. (557 aa)
hprKHPr kinase/phosphorylase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon [...] (310 aa)
pstB-3Phosphate ABC transporter ATP-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family. (203 aa)
APD32152.1Peptide ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (207 aa)
smcChromosome segregation protein SMC; Required for chromosome condensation and partitioning. Belongs to the SMC family. (1181 aa)
APD32161.1ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (265 aa)
APD32852.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (133 aa)
APD32177.1Sugar ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (330 aa)
thrSthreonine--tRNA ligase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). (646 aa)
coaEdephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (203 aa)
APD32209.1UDP kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (135 aa)
APD32212.1Phosphate starvation-inducible protein PhoH; Derived by automated computational analysis using gene prediction method: Protein Homology. (354 aa)
pyrHUMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (244 aa)
APD32224.1Cell division protein FtsK; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FtsK/SpoIIIE/SftA family. (801 aa)
mtsBManganese ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (242 aa)
metGmethionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily. (667 aa)
tmkdTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (210 aa)
APD32266.1ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (236 aa)
APD32267.1ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (254 aa)
murEUDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of L-lysine to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan; Belongs to the MurCDEF family. MurE subfamily. (481 aa)
APD32278.1Iron ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (260 aa)
APD32289.1ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (276 aa)
murCUDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (443 aa)
APD32317.1RNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1029 aa)
APD32319.1Primosomal protein that may act to load helicase DnaC during DNA replication; Derived by automated computational analysis using gene prediction method: Protein Homology. (300 aa)
nrdRTranscriptional regulator NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. (164 aa)
metNMethionine ABC transporter ATP-binding protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. (354 aa)
tmcALHypothetical protein; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac- AMP) and then transfers the acetyl group to tRNA to form ac(4)C34. (368 aa)
nadDNicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (210 aa)
APD32352.1DNA/RNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (432 aa)
APD32359.1Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (334 aa)
pknBSerine/threonine protein kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (634 aa)
priAPrimosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (795 aa)
gmkGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (208 aa)
nadENAD(+) synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. (274 aa)
APD32382.1Amino acid ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (247 aa)
cshBDEAD/DEAH box helicase; Probable DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures. (447 aa)
proBGlutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (267 aa)
APD32391.13-dehydroquinate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (244 aa)
glpKGlycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. (504 aa)
glySglycine--tRNA ligase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. (679 aa)
glyQglycine--tRNA ligase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (307 aa)
APD32411.1Copper-translocating P-type ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (752 aa)
APD32424.1Multidrug ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (343 aa)
APD32425.1Multidrug ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (241 aa)
serSserine--tRNA ligase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (425 aa)
accAacetyl-CoA carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (256 aa)
accDacetyl-CoA carboxylase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (288 aa)
accCacetyl-CoA carboxylase biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (454 aa)
dnaJMolecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] (378 aa)
dnaKMolecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. (607 aa)
gatBaspartyl/glutamyl-tRNA amidotransferase subunit B; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily. (479 aa)
gatAaspartyl/glutamyl-tRNA amidotransferase subunit A; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). (488 aa)
gatCasparaginyl/glutamyl-tRNA amidotransferase subunit C; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family. (100 aa)
APD32467.1Pyruvate, phosphate dikinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the PEP-utilizing enzyme family. (881 aa)
APD32468.1Phosphoenolpyruvate synthase regulatory protein; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation. (279 aa)
recGATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (671 aa)
APD32482.1ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (479 aa)
APD32485.1ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (561 aa)
APD32486.1ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (591 aa)
APD32487.1Iron ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (263 aa)
secAPreprotein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. (844 aa)
uvrAExcinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (940 aa)
mutS2Endonuclease MutS2; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily. (778 aa)
recD2Exodeoxyribonuclease V subunit alpha; DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity; Belongs to the RecD family. RecD-like subfamily. (793 aa)
essCType VII secretion protein EssC; Derived by automated computational analysis using gene prediction method: Protein Homology. (1469 aa)
APD32564.1Protein kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (490 aa)
APD32569.1Cell division protein FtsK; Derived by automated computational analysis using gene prediction method: Protein Homology. (389 aa)
APD32571.1Replication protein RepA; Derived by automated computational analysis using gene prediction method: Protein Homology. (395 aa)
APD32586.1ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily. (311 aa)
APD32587.1Peptide ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily. (348 aa)
pgkPhosphoglycerate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phosphoglycerate kinase family. (398 aa)
APD32600.1Surface exclusion protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (877 aa)
APD32604.1Thiamine diphosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (210 aa)
APD32638.1ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (286 aa)
argGArgininosuccinate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (399 aa)
gltXglutamate--tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (481 aa)
radADNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. (454 aa)
APD32665.1Multidrug ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (594 aa)
APD32666.1Multidrug ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (569 aa)
APD32670.15-formyltetrahydrofolate cyclo-ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (177 aa)
APD32691.1Glycine betaine/L-proline ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (408 aa)
APD32692.1Diacylglycerol kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (294 aa)
leuSleucine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. (833 aa)
groLChaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. (542 aa)
groSCo-chaperone GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. (96 aa)
APD32728.1Chaperone protein ClpB; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ClpA/ClpB family. (815 aa)
APD32750.1Anaerobic ribonucleoside-triphosphate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (731 aa)
recARecombinase RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (377 aa)
ruvAHolliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (197 aa)
mutLDNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. (652 aa)
mutSDNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. (846 aa)
argSarginine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (562 aa)
aspSaspartate--tRNA ligase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (582 aa)
hisShistidine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (424 aa)
APD32790.1Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (452 aa)
mnmAtRNA 2-thiouridine(34) synthase MnmA; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (373 aa)
ecfAEnergy-coupling factor transporter ATPase; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. (280 aa)
ecfA-2Energy-coupling factor transporter ATPase; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. (279 aa)
recFDNA replication/repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family. (364 aa)
trpStryptophan--tRNA ligase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. (340 aa)
APD32812.1ABC-F family ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (539 aa)
Your Current Organism:
Streptococcus iniae
NCBI taxonomy Id: 1346
Other names: ATCC 29178, CCUG 27303, CIP 102508, DSM 20576, LMG 14520, LMG:14520, S. iniae, Streptococcus shiloi, strain PW
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