8 items (Streptococcus iniae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	APD31638.1	Pyruvate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (322 aa)
	citF	Citrate lyase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (510 aa)
	ackA	Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (398 aa)
	citE	Citrate (pro-3S)-lyase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HpcH/HpaI aldolase family. (295 aa)
	mvaD	Diphosphomevalonate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (314 aa)
	APD31918.1	Phosphomevalonate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (339 aa)
	APD31915.1	hydroxymethylglutaryl-CoA synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (390 aa)
	APD31640.1	Iron ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (471 aa)

Your Current Organism:

Streptococcus iniae

NCBI taxonomy Id: 1346
Other names: ATCC 29178, CCUG 27303, CIP 102508, DSM 20576, LMG 14520, LMG:14520, S. iniae, Streptococcus shiloi, strain PW

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APD31638.1	APD31640.1	BMF34_03890	BMF34_03900	Pyruvate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Iron ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.998
APD31638.1	ackA	BMF34_03890	BMF34_00955	Pyruvate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.	0.403
APD31640.1	APD31638.1	BMF34_03900	BMF34_03890	Iron ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Pyruvate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.998
APD31640.1	APD31915.1	BMF34_03900	BMF34_05370	Iron ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	hydroxymethylglutaryl-CoA synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.532
APD31640.1	ackA	BMF34_03900	BMF34_00955	Iron ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.	0.639
APD31640.1	citE	BMF34_03900	BMF34_01965	Iron ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Citrate (pro-3S)-lyase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HpcH/HpaI aldolase family.	0.490
APD31915.1	APD31640.1	BMF34_05370	BMF34_03900	hydroxymethylglutaryl-CoA synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Iron ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.532
APD31915.1	APD31918.1	BMF34_05370	BMF34_05385	hydroxymethylglutaryl-CoA synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phosphomevalonate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.908
APD31915.1	mvaD	BMF34_05370	BMF34_05390	hydroxymethylglutaryl-CoA synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Diphosphomevalonate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.915
APD31918.1	APD31915.1	BMF34_05385	BMF34_05370	Phosphomevalonate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	hydroxymethylglutaryl-CoA synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.908
APD31918.1	mvaD	BMF34_05385	BMF34_05390	Phosphomevalonate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Diphosphomevalonate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.989
ackA	APD31638.1	BMF34_00955	BMF34_03890	Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.	Pyruvate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.403
ackA	APD31640.1	BMF34_00955	BMF34_03900	Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.	Iron ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.639
citE	APD31640.1	BMF34_01965	BMF34_03900	Citrate (pro-3S)-lyase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HpcH/HpaI aldolase family.	Iron ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.490
citE	citF	BMF34_01965	BMF34_01970	Citrate (pro-3S)-lyase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HpcH/HpaI aldolase family.	Citrate lyase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.998
citF	citE	BMF34_01970	BMF34_01965	Citrate lyase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.	Citrate (pro-3S)-lyase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HpcH/HpaI aldolase family.	0.998
mvaD	APD31915.1	BMF34_05390	BMF34_05370	Diphosphomevalonate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	hydroxymethylglutaryl-CoA synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.915
mvaD	APD31918.1	BMF34_05390	BMF34_05385	Diphosphomevalonate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phosphomevalonate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.989