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APD31289.1 APD31289.1 APD31232.1 APD31232.1 APD31231.1 APD31231.1 APD31089.1 APD31089.1 APD31088.1 APD31088.1 BMF34_00825 BMF34_00825 plsX plsX APD31009.1 APD31009.1 APD31025.1 APD31025.1 APD32209.1 APD32209.1 accA accA accD accD accC accC fabZ fabZ APD32444.1 APD32444.1 fabF fabF fabG fabG fabD fabD acpP acpP fabH fabH APD32452.1 APD32452.1 acpS acpS gpsA gpsA APD32692.1 APD32692.1 APD32785.1 APD32785.1 pgsA pgsA APD32404.1 APD32404.1 glmU glmU APD32197.1 APD32197.1 APD32181.1 APD32181.1 APD32180.1 APD32180.1 APD32026.1 APD32026.1 mvk mvk mvaD mvaD APD31918.1 APD31918.1 fni fni APD31915.1 APD31915.1 APD31788.1 APD31788.1 cls cls plsY plsY APD31687.1 APD31687.1 cpsC cpsC APD31664.1 APD31664.1 APD31650.1 APD31650.1 APD31486.1 APD31486.1 APD31455.1 APD31455.1 APD31349.1 APD31349.1 citD citD
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
APD31289.1Composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism; Derived by automated computational analysis using gene prediction method: Protein Homology. (133 aa)
APD31232.1Phosphatidate cytidylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CDS family. (264 aa)
APD31231.1Isoprenyl transferase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (249 aa)
APD31089.14-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol; Belongs to the GHMP kinase family. IspE subfamily. (283 aa)
APD31088.1Farnesyl pyrophosphate synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FPP/GGPP synthase family. (325 aa)
BMF34_00825UDP-N-acetylmuramoylpentapeptide-lysine N(6)-alanyltransferase; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. (176 aa)
plsXPhosphate acyltransferase; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (331 aa)
APD31009.1Acyl carrier protein; Carries the fatty acid chain in fatty acid biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (78 aa)
APD31025.1Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (592 aa)
APD32209.1UDP kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (135 aa)
accAacetyl-CoA carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (256 aa)
accDacetyl-CoA carboxylase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (288 aa)
accCacetyl-CoA carboxylase biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (454 aa)
fabZ3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (141 aa)
APD32444.1acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (146 aa)
fabFBeta-ketoacyl-[acyl-carrier-protein] synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (410 aa)
fabG3-oxoacyl-[acyl-carrier-protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (244 aa)
fabD[acyl-carrier-protein] S-malonyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (309 aa)
acpPAcyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. (74 aa)
fabH3-oxoacyl-ACP synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (324 aa)
APD32452.1enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (263 aa)
acpSholo-ACP synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. (117 aa)
gpsAGlycerol-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (338 aa)
APD32692.1Diacylglycerol kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (294 aa)
APD32785.1DUF368 domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (280 aa)
pgsACDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (180 aa)
APD32404.12,5-diketo-D-gluconic acid reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (279 aa)
glmUUDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (461 aa)
APD32197.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (212 aa)
APD32181.1Glycosyl transferase family 1; Derived by automated computational analysis using gene prediction method: Protein Homology. (332 aa)
APD32180.11,2-diacylglycerol 3-glucosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (445 aa)
APD32026.1Diacylglycerol kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (343 aa)
mvkMevalonate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (294 aa)
mvaDDiphosphomevalonate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (314 aa)
APD31918.1Phosphomevalonate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (339 aa)
fniType 2 isopentenyl-diphosphate Delta-isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). (331 aa)
APD31915.1hydroxymethylglutaryl-CoA synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (390 aa)
APD31788.1Diacylglycerol kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (300 aa)
clsCardiolipin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phospholipase D family. Cardiolipin synthase subfamily. (505 aa)
plsYGlycerol-3-phosphate acyltransferase; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. (211 aa)
APD31687.1Capsular biosynthesis protein CpsH; Derived by automated computational analysis using gene prediction method: Protein Homology. (340 aa)
cpsCCapsular biosynthesis protein CpsC; Derived by automated computational analysis using gene prediction method: Protein Homology. (229 aa)
APD31664.12,5-diketo-D-gluconic acid reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (281 aa)
APD31650.1Acyl-[acyl-carrier-protein] thioesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (244 aa)
APD31486.11-acyl-sn-glycerol-3-phosphate acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (245 aa)
APD31455.1Geranyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FPP/GGPP synthase family. (290 aa)
APD31349.1Family 8 glycosyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (401 aa)
citDCitrate lyase acyl carrier protein; Covalent carrier of the coenzyme of citrate lyase. (101 aa)
Your Current Organism:
Streptococcus iniae
NCBI taxonomy Id: 1346
Other names: ATCC 29178, CCUG 27303, CIP 102508, DSM 20576, LMG 14520, LMG:14520, S. iniae, Streptococcus shiloi, strain PW
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