STRINGSTRING
deoC deoC lacD lacD APD31021.1 APD31021.1 APD31027.1 APD31027.1 APD31132.1 APD31132.1 APD31135.1 APD31135.1 APD31146.1 APD31146.1 APD31155.1 APD31155.1 APD31157.1 APD31157.1 APD31204.1 APD31204.1 citC citC APD31289.1 APD31289.1 APD31290.1 APD31290.1 citE citE citF citF APD31295.1 APD31295.1 APD31296.1 APD31296.1 APD31318.1 APD31318.1 APD31530.1 APD31530.1 uxuA uxuA nth nth rfbB rfbB dacA dacA APD31684.1 APD31684.1 pyrF pyrF dapA dapA APD31837.1 APD31837.1 folB folB mvaD mvaD aroC aroC aroD aroD eno eno APD32042.1 APD32042.1 ppc ppc APD32096.1 APD32096.1 APD32103.1 APD32103.1 hutH hutH hutU hutU APD32137.1 APD32137.1 APD32186.1 APD32186.1 mutM mutM APD32214.1 APD32214.1 aroB aroB APD32287.1 APD32287.1 APD32303.1 APD32303.1 mltG mltG luxS luxS fsa fsa fabZ fabZ APD32619.1 APD32619.1 argH argH APD32652.1 APD32652.1 APD32694.1 APD32694.1 APD32696.1 APD32696.1 BMF34_09535 BMF34_09535 APD32703.1 APD32703.1 ulaD ulaD sdaAB sdaAB sdaAA sdaAA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
deoCDeoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (220 aa)
lacDTagatose-bisphosphate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldolase LacD family. (326 aa)
APD31021.1Adenylosuccinate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (430 aa)
APD31027.1Threonine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (494 aa)
APD31132.1Pyruvate formate lyase-activating protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (258 aa)
APD31135.1Similar to transaldolase from Escherichia coli; many organisms have multiple copies; Derived by automated computational analysis using gene prediction method: Protein Homology. (222 aa)
APD31146.1Bifunctional 2-keto-4-hydroxyglutarate aldolase/2-keto-3-deoxy-6-phosphogluconate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (213 aa)
APD31155.1Oligohyaluronate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (638 aa)
APD31157.1Hyaluronate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1167 aa)
APD31204.1Anthranilate synthase component II; Derived by automated computational analysis using gene prediction method: Protein Homology. (191 aa)
citC[citrate (pro-3S)-lyase] ligase; Acetylation of prosthetic group (2-(5''-phosphoribosyl)-3'- dephosphocoenzyme-A) of the gamma subunit of citrate lyase. (348 aa)
APD31289.1Composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism; Derived by automated computational analysis using gene prediction method: Protein Homology. (133 aa)
APD31290.1glutaconyl-CoA decarboxylase subunit beta; Tunnel subunit of the primary sodium pump glutaconyl-CoA decarboxylase (GCD). (373 aa)
citECitrate (pro-3S)-lyase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HpcH/HpaI aldolase family. (295 aa)
citFCitrate lyase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (510 aa)
APD31295.1Converts oxaloacetate to phosphoenolpyruvate using ATP as an energy source; Derived by automated computational analysis using gene prediction method: Protein Homology. (462 aa)
APD31296.1Phosphoenolpyruvate carboxykinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (546 aa)
APD31318.1Fructose-1,6-bisphosphate aldolase, class II; Derived by automated computational analysis using gene prediction method: Protein Homology. (293 aa)
APD31530.12-dehydro-3-deoxyphosphogluconate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (205 aa)
uxuAMannonate dehydratase; Catalyzes the dehydration of D-mannonate. (348 aa)
nthEndonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (218 aa)
rfbBdTDP-glucose 4,6-dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (348 aa)
dacATIGR00159 family protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. (281 aa)
APD31684.1Polysaccharide biosynthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (600 aa)
pyrFOrotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (243 aa)
dapA4-hydroxy-tetrahydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (309 aa)
APD31837.1VOC family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (137 aa)
folBDihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (119 aa)
mvaDDiphosphomevalonate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (314 aa)
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (388 aa)
aroD3-dehydroquinate dehydratase; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family. (225 aa)
enoPhosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (435 aa)
APD32042.1Glyoxalase; Derived by automated computational analysis using gene prediction method: Protein Homology. (143 aa)
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (906 aa)
APD32096.1aminoacyl-tRNA deacylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. (157 aa)
APD32103.1LuxR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (1023 aa)
hutHHistidine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (513 aa)
hutUUrocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate. (676 aa)
APD32137.1Glyoxalase; Derived by automated computational analysis using gene prediction method: Protein Homology. (127 aa)
APD32186.1Lactoylglutathione lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (126 aa)
mutMDNA-formamidopyrimidine glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. (279 aa)
APD32214.1Oleate hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (590 aa)
aroB3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (358 aa)
APD32287.13-deoxy-7-phosphoheptulonate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (249 aa)
APD32303.1Diaminopimelate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (412 aa)
mltGAminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family. (530 aa)
luxSS-ribosylhomocysteine lyase; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. (160 aa)
fsaFructose-6-phosphate aldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (214 aa)
fabZ3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (141 aa)
APD32619.1N-acetylneuraminate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (305 aa)
argHArgininosuccinate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (460 aa)
APD32652.1Carbonate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (166 aa)
APD32694.1Deoxyribodipyrimidine photolyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DNA photolyase family. (470 aa)
APD32696.1AP endonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. (248 aa)
BMF34_09535Carbohydrate kinase; Internal stop; Derived by automated computational analysis using gene prediction method: Protein Homology. (329 aa)
APD32703.1Xylulose 5-phosphate 3-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (287 aa)
ulaDCatalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate in anaerobic L-ascorbate utilization; Derived by automated computational analysis using gene prediction method: Protein Homology. (221 aa)
sdaABL-serine dehydratase, iron-sulfur-dependent subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the iron-sulfur dependent L-serine dehydratase family. (223 aa)
sdaAAL-serine dehydratase, iron-sulfur-dependent subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the iron-sulfur dependent L-serine dehydratase family. (290 aa)
Your Current Organism:
Streptococcus iniae
NCBI taxonomy Id: 1346
Other names: ATCC 29178, CCUG 27303, CIP 102508, DSM 20576, LMG 14520, LMG:14520, S. iniae, Streptococcus shiloi, strain PW
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