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APD31120.1 APD31120.1 APD32745.1 APD32745.1 APD32778.1 APD32778.1 BMF34_02645 BMF34_02645 arcC arcC rbsK rbsK ptsP ptsP udk udk APD31528.1 APD31528.1 aroK aroK APD31658.1 APD31658.1 hk hk epsD epsD APD31700.1 APD31700.1 pfkA pfkA pyk pyk APD31723.1 APD31723.1 APD31750.1 APD31750.1 APD31761.1 APD31761.1 coaA coaA APD31788.1 APD31788.1 APD31811.1 APD31811.1 tdk tdk prs prs adk adk APD31089.1 APD31089.1 ackA ackA APD31147.1 APD31147.1 nadK nadK APD31865.1 APD31865.1 prs-2 prs-2 APD31880.1 APD31880.1 APD31886.1 APD31886.1 folK folK thrB thrB APD31160.1 APD31160.1 APD31187.1 APD31187.1 APD31188.1 APD31188.1 APD31202.1 APD31202.1 APD31212.1 APD31212.1 galK galK APD31258.1 APD31258.1 APD31296.1 APD31296.1 APD31304.1 APD31304.1 APD31306.1 APD31306.1 APD31918.1 APD31918.1 mvaD mvaD mvk mvk pfkB pfkB APD31313.1 APD31313.1 APD31385.1 APD31385.1 cmk cmk APD32026.1 APD32026.1 hprK hprK APD32135.1 APD32135.1 APD32144.1 APD32144.1 vicK vicK APD32167.1 APD32167.1 dhaL dhaL APD32169.1 APD32169.1 APD32170.1 APD32170.1 coaE coaE APD32209.1 APD32209.1 pyrH pyrH tmk tmk APD32860.1 APD32860.1 APD32359.1 APD32359.1 pknB pknB gmk gmk proB proB glpK glpK APD32467.1 APD32467.1 APD32468.1 APD32468.1 APD32496.1 APD32496.1 APD32564.1 APD32564.1 pgk pgk APD32604.1 APD32604.1 arcC-2 arcC-2 APD32647.1 APD32647.1 APD32648.1 APD32648.1 APD32692.1 APD32692.1 APD32873.1 APD32873.1 APD32743.1 APD32743.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
APD31120.1Deoxynucleoside kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (214 aa)
APD32745.1PTS beta-glucoside transporter subunit EIIBCA; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology. (650 aa)
APD32778.1Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (345 aa)
BMF34_02645Hypothetical protein; Incomplete; partial on complete genome; missing start; Derived by automated computational analysis using gene prediction method: Protein Homology. (554 aa)
arcCCarbamate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the carbamate kinase family. (316 aa)
rbsKRibokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (303 aa)
ptsPPhosphoenolpyruvate--protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (577 aa)
udkUridine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (208 aa)
APD31528.12-dehydro-3-deoxygluconokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (341 aa)
aroKShikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (172 aa)
APD31658.1Nucleoside-diphosphate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (140 aa)
hkLytR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (261 aa)
epsDTyrosine protein kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (239 aa)
APD31700.1Phosphatidylethanolamine-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (166 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (337 aa)
pykPyruvate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pyruvate kinase family. (500 aa)
APD31723.1Phosphotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (650 aa)
APD31750.1Riboflavin biosynthesis protein RibF; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribF family. (310 aa)
APD31761.1Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (436 aa)
coaAType I pantothenate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (306 aa)
APD31788.1Diacylglycerol kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (300 aa)
APD31811.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (102 aa)
tdkThymidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (192 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (321 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (212 aa)
APD31089.14-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol; Belongs to the GHMP kinase family. IspE subfamily. (283 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (398 aa)
APD31147.12-keto-3-deoxygluconate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (335 aa)
nadKNAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (278 aa)
APD31865.1GTP pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (223 aa)
prs-2Ribose-phosphate diphosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (323 aa)
APD31880.1PTS beta-glucoside transporter subunit IIABC; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology. (639 aa)
APD31886.1Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (506 aa)
folK2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (163 aa)
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (286 aa)
APD31160.1Sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (362 aa)
APD31187.1Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (353 aa)
APD31188.1Phosphoribulokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (198 aa)
APD31202.1Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (447 aa)
APD31212.1PTS glucose/maltose transporter subunit IIBCA; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology. (726 aa)
galKGalactokinase; Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily. (387 aa)
APD31258.1Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (545 aa)
APD31296.1Phosphoenolpyruvate carboxykinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (546 aa)
APD31304.1Aspartate kinase; Catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; lysine and threonine sensitive; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartokinase family. (450 aa)
APD31306.1Phosphomethylpyrimidine kinase; Catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine; Derived by automated computational analysis using gene prediction method: Protein Homology. (255 aa)
APD31918.1Phosphomevalonate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (339 aa)
mvaDDiphosphomevalonate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (314 aa)
mvkMevalonate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (294 aa)
pfkB1-phosphofructokinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the carbohydrate kinase PfkB family. LacC subfamily. (303 aa)
APD31313.1Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (583 aa)
APD31385.1Shikimate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (187 aa)
cmkCytidylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (226 aa)
APD32026.1Diacylglycerol kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (343 aa)
hprKHPr kinase/phosphorylase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon [...] (310 aa)
APD32135.1Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (442 aa)
APD32144.1Transcription antiterminator BglG; Derived by automated computational analysis using gene prediction method: Protein Homology. (665 aa)
vicKCell wall metabolism sensor histidine kinase VicK; Derived by automated computational analysis using gene prediction method: Protein Homology. (452 aa)
APD32167.1PTS-dependent dihydroxyacetone kinase phosphotransferase subunit DhaM; Derived by automated computational analysis using gene prediction method: Protein Homology. (124 aa)
dhaLDihydroxyacetone kinase subunit L; Derived by automated computational analysis using gene prediction method: Protein Homology. (191 aa)
APD32169.1Dihydroxyacetone kinase subunit DhaK; Derived by automated computational analysis using gene prediction method: Protein Homology. (329 aa)
APD32170.1Dihydroxyacetone kinase transcriptional activator DhaS; Derived by automated computational analysis using gene prediction method: Protein Homology. (181 aa)
coaEdephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (203 aa)
APD32209.1UDP kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (135 aa)
pyrHUMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (244 aa)
tmkdTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (210 aa)
APD32860.1Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (495 aa)
APD32359.1Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (334 aa)
pknBSerine/threonine protein kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (634 aa)
gmkGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (208 aa)
proBGlutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (267 aa)
glpKGlycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. (504 aa)
APD32467.1Pyruvate, phosphate dikinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the PEP-utilizing enzyme family. (881 aa)
APD32468.1Phosphoenolpyruvate synthase regulatory protein; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation. (279 aa)
APD32496.1PTS beta-glucoside transporter subunit EIIBCA; Derived by automated computational analysis using gene prediction method: Protein Homology. (622 aa)
APD32564.1Protein kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (490 aa)
pgkPhosphoglycerate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phosphoglycerate kinase family. (398 aa)
APD32604.1Thiamine diphosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (210 aa)
arcC-2Carbamate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the carbamate kinase family. (310 aa)
APD32647.1Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (438 aa)
APD32648.1Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (436 aa)
APD32692.1Diacylglycerol kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (294 aa)
APD32873.1Glycerate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycerate kinase type-1 family. (353 aa)
APD32743.1Transcription antiterminator BglG; Derived by automated computational analysis using gene prediction method: Protein Homology. (679 aa)
Your Current Organism:
Streptococcus iniae
NCBI taxonomy Id: 1346
Other names: ATCC 29178, CCUG 27303, CIP 102508, DSM 20576, LMG 14520, LMG:14520, S. iniae, Streptococcus shiloi, strain PW
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