(32 nodes) beta-Lactam resistance network (Streptococcus iniae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	APD32589.1	Peptide ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (304 aa)
	APD32588.1	Peptide ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (343 aa)
	APD32587.1	Peptide ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily. (348 aa)
	APD32586.1	ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily. (311 aa)
	APD32412.1	Uracil phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (145 aa)
	APD32386.1	Penicillin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (750 aa)
	APD32375.1	Penicillin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (735 aa)
	APD32170.1	Dihydroxyacetone kinase transcriptional activator DhaS; Derived by automated computational analysis using gene prediction method: Protein Homology. (181 aa)
	APD32115.1	ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (549 aa)
	APD31949.1	Efflux transporter periplasmic adaptor subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (414 aa)
	APD31079.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (112 aa)
	APD31741.1	TetR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (182 aa)
	APD30989.1	Serine hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (428 aa)
	APD31080.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (97 aa)
	APD31094.1	Transglycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (768 aa)
	APD31190.1	FMN adenylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (397 aa)
	APD31241.1	MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (389 aa)
	bug4	Peptide ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (659 aa)
	APD31338.1	Peptide ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (499 aa)
	APD31339.1	Peptide ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (308 aa)
	APD31340.1	Oligopeptide transport ATP-binding protein AmiE; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily. (356 aa)
	APD31341.1	Peptide ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily. (307 aa)
	APD31471.1	Penicillin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (694 aa)
	APD31490.1	D-alanyl-D-alanine carboxypeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (360 aa)
	APD31536.1	Beta-hexosaminidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (596 aa)
	APD31570.1	MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (406 aa)
	APD32787.1	TetR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (178 aa)
	APD32783.1	TetR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (175 aa)
	APD32762.1	MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (407 aa)
	APD32718.1	Penicillin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (772 aa)
	APD32592.1	MerR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (122 aa)
	APD32590.1	ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (551 aa)

Your Current Organism:

Streptococcus iniae

NCBI taxonomy Id: 1346
Other names: ATCC 29178, CCUG 27303, CIP 102508, DSM 20576, LMG 14520, LMG:14520, S. iniae, Streptococcus shiloi, strain PW

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APD30989.1	APD31094.1	BMF34_00055	BMF34_00895	Serine hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Transglycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.492
APD30989.1	APD31490.1	BMF34_00055	BMF34_03120	Serine hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	D-alanyl-D-alanine carboxypeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.652
APD30989.1	APD31949.1	BMF34_00055	BMF34_05555	Serine hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Efflux transporter periplasmic adaptor subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.432
APD30989.1	APD32375.1	BMF34_00055	BMF34_07840	Serine hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Penicillin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.502
APD30989.1	APD32718.1	BMF34_00055	BMF34_09645	Serine hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Penicillin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.517
APD31079.1	APD31080.1	BMF34_00810	BMF34_00815	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.946
APD31080.1	APD31079.1	BMF34_00815	BMF34_00810	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.946
APD31094.1	APD30989.1	BMF34_00895	BMF34_00055	Transglycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Serine hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.492
APD31094.1	APD31471.1	BMF34_00895	BMF34_03020	Transglycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Penicillin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.851
APD31094.1	APD32375.1	BMF34_00895	BMF34_07840	Transglycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Penicillin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.648
APD31094.1	APD32386.1	BMF34_00895	BMF34_07900	Transglycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Penicillin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.870
APD31094.1	APD32718.1	BMF34_00895	BMF34_09645	Transglycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Penicillin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.647
APD31338.1	APD31339.1	BMF34_02245	BMF34_02250	Peptide ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Peptide ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.998
APD31338.1	APD31340.1	BMF34_02245	BMF34_02255	Peptide ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Oligopeptide transport ATP-binding protein AmiE; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily.	0.981
APD31338.1	APD31341.1	BMF34_02245	BMF34_02260	Peptide ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Peptide ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily.	0.979
APD31338.1	APD32115.1	BMF34_02245	BMF34_06415	Peptide ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.756
APD31338.1	APD32586.1	BMF34_02245	BMF34_08945	Peptide ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily.	0.890
APD31338.1	APD32587.1	BMF34_02245	BMF34_08950	Peptide ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Peptide ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily.	0.904
APD31338.1	APD32588.1	BMF34_02245	BMF34_08955	Peptide ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Peptide ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.907
APD31338.1	APD32590.1	BMF34_02245	BMF34_08965	Peptide ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.754