(11 nodes) Iron-sulfur cluster assembly, and Aminotransferase class V domain network (Actinoplanes sp. SE50110)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ACPL_1870	Predicted transcriptional regulator. (242 aa)
	sufB	ABC-type transport system involved in Fe-S cluster assembly, permease component. (473 aa)
	ACPL_1872	Uncharacterized protein; ABC-type transport system involved in Fe-S cluster assembly, permease component. (373 aa)
	bedB	Benzene 1,2-dioxygenase system ferredoxin subunit; Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases. (110 aa)
	ACPL_1874	Spermidine/putrescine import ATP-binding protein potA; ABC-type oligopeptide transport system, ATPase component. (252 aa)
	csdB	Cysteine desulfurase / selenocysteine lyase; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. (409 aa)
	iscU	Similar to mitochondrial Iron sulfur cluster assembly protein 1; NifU homolog involved in Fe-S cluster formation. (151 aa)
	ACPL_1877	yitW-like uncharacterized protein; Predicted metal-sulfur cluster biosynthetic enzyme. (265 aa)
	ACPL_2281	Selenocysteine lyase. (408 aa)
	fdxR	ferredoxin-NADP+ reductase; NADPH-dependent glutamate synthase beta chain and related oxidoreductases. (449 aa)
	ACPL_4950	Cysteine desulfurase family protein; Selenocysteine lyase. (400 aa)

Your Current Organism:

Actinoplanes sp. SE50110

NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACPL_1870	ACPL_1872	ACPL_1870	ACPL_1872	Predicted transcriptional regulator.	Uncharacterized protein; ABC-type transport system involved in Fe-S cluster assembly, permease component.	0.887
ACPL_1870	ACPL_1874	ACPL_1870	ACPL_1874	Predicted transcriptional regulator.	Spermidine/putrescine import ATP-binding protein potA; ABC-type oligopeptide transport system, ATPase component.	0.869
ACPL_1870	ACPL_1877	ACPL_1870	ACPL_1877	Predicted transcriptional regulator.	yitW-like uncharacterized protein; Predicted metal-sulfur cluster biosynthetic enzyme.	0.853
ACPL_1870	bedB	ACPL_1870	ACPL_1873	Predicted transcriptional regulator.	Benzene 1,2-dioxygenase system ferredoxin subunit; Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases.	0.864
ACPL_1870	csdB	ACPL_1870	ACPL_1875	Predicted transcriptional regulator.	Cysteine desulfurase / selenocysteine lyase; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.	0.856
ACPL_1870	iscU	ACPL_1870	ACPL_1876	Predicted transcriptional regulator.	Similar to mitochondrial Iron sulfur cluster assembly protein 1; NifU homolog involved in Fe-S cluster formation.	0.895
ACPL_1870	sufB	ACPL_1870	ACPL_1871	Predicted transcriptional regulator.	ABC-type transport system involved in Fe-S cluster assembly, permease component.	0.985
ACPL_1872	ACPL_1870	ACPL_1872	ACPL_1870	Uncharacterized protein; ABC-type transport system involved in Fe-S cluster assembly, permease component.	Predicted transcriptional regulator.	0.887
ACPL_1872	ACPL_1874	ACPL_1872	ACPL_1874	Uncharacterized protein; ABC-type transport system involved in Fe-S cluster assembly, permease component.	Spermidine/putrescine import ATP-binding protein potA; ABC-type oligopeptide transport system, ATPase component.	0.999
ACPL_1872	ACPL_1877	ACPL_1872	ACPL_1877	Uncharacterized protein; ABC-type transport system involved in Fe-S cluster assembly, permease component.	yitW-like uncharacterized protein; Predicted metal-sulfur cluster biosynthetic enzyme.	0.964
ACPL_1872	ACPL_2281	ACPL_1872	ACPL_2281	Uncharacterized protein; ABC-type transport system involved in Fe-S cluster assembly, permease component.	Selenocysteine lyase.	0.907
ACPL_1872	ACPL_4950	ACPL_1872	ACPL_4950	Uncharacterized protein; ABC-type transport system involved in Fe-S cluster assembly, permease component.	Cysteine desulfurase family protein; Selenocysteine lyase.	0.828
ACPL_1872	bedB	ACPL_1872	ACPL_1873	Uncharacterized protein; ABC-type transport system involved in Fe-S cluster assembly, permease component.	Benzene 1,2-dioxygenase system ferredoxin subunit; Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases.	0.926
ACPL_1872	csdB	ACPL_1872	ACPL_1875	Uncharacterized protein; ABC-type transport system involved in Fe-S cluster assembly, permease component.	Cysteine desulfurase / selenocysteine lyase; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.	0.986
ACPL_1872	iscU	ACPL_1872	ACPL_1876	Uncharacterized protein; ABC-type transport system involved in Fe-S cluster assembly, permease component.	Similar to mitochondrial Iron sulfur cluster assembly protein 1; NifU homolog involved in Fe-S cluster formation.	0.995
ACPL_1872	sufB	ACPL_1872	ACPL_1871	Uncharacterized protein; ABC-type transport system involved in Fe-S cluster assembly, permease component.	ABC-type transport system involved in Fe-S cluster assembly, permease component.	0.945
ACPL_1874	ACPL_1870	ACPL_1874	ACPL_1870	Spermidine/putrescine import ATP-binding protein potA; ABC-type oligopeptide transport system, ATPase component.	Predicted transcriptional regulator.	0.869
ACPL_1874	ACPL_1872	ACPL_1874	ACPL_1872	Spermidine/putrescine import ATP-binding protein potA; ABC-type oligopeptide transport system, ATPase component.	Uncharacterized protein; ABC-type transport system involved in Fe-S cluster assembly, permease component.	0.999
ACPL_1874	ACPL_1877	ACPL_1874	ACPL_1877	Spermidine/putrescine import ATP-binding protein potA; ABC-type oligopeptide transport system, ATPase component.	yitW-like uncharacterized protein; Predicted metal-sulfur cluster biosynthetic enzyme.	0.981
ACPL_1874	ACPL_2281	ACPL_1874	ACPL_2281	Spermidine/putrescine import ATP-binding protein potA; ABC-type oligopeptide transport system, ATPase component.	Selenocysteine lyase.	0.923