STRINGSTRING
whiB whiB ACPL_1052 ACPL_1052 ACPL_1053 ACPL_1053 ACPL_120 ACPL_120 ACPL_125 ACPL_125 hrdB hrdB ACPL_1401 ACPL_1401 ACPL_1403 ACPL_1403 ACPL_1507 ACPL_1507 ACPL_1519 ACPL_1519 ACPL_1526 ACPL_1526 ACPL_1529 ACPL_1529 ACPL_1532 ACPL_1532 ACPL_1534 ACPL_1534 ahpE ahpE ACPL_1536 ACPL_1536 ACPL_1579 ACPL_1579 ACPL_1606 ACPL_1606 ACPL_1633 ACPL_1633 ACPL_1647 ACPL_1647 ACPL_1744 ACPL_1744 ACPL_1818 ACPL_1818 ACPL_1849 ACPL_1849 ACPL_1851 ACPL_1851 ACPL_1852 ACPL_1852 whiA whiA rbpA rbpA ACPL_1926 ACPL_1926 ACPL_235 ACPL_235 ACPL_240 ACPL_240 ACPL_2405 ACPL_2405 ACPL_2408 ACPL_2408 rbpA-2 rbpA-2 ACPL_285 ACPL_285 ACPL_3016 ACPL_3016 ACPL_3836 ACPL_3836 ACPL_4659 ACPL_4659 ACPL_4757 ACPL_4757 ACPL_4758 ACPL_4758 ACPL_5070 ACPL_5070 ACPL_5224 ACPL_5224 ACPL_5228 ACPL_5228 pafC pafC pafB pafB ACPL_5231 ACPL_5231 ACPL_5232 ACPL_5232 ACPL_538 ACPL_538 gylR gylR ACPL_5929 ACPL_5929 ogt-2 ogt-2 ACPL_6657 ACPL_6657 ACPL_6658 ACPL_6658 lsr2 lsr2 ACPL_7087 ACPL_7087 ACPL_7101 ACPL_7101 ACPL_7102 ACPL_7102 trkA trkA trkA-2 trkA-2 ACPL_7105 ACPL_7105 ACPL_7106 ACPL_7106 ACPL_7107 ACPL_7107 ACPL_7109 ACPL_7109 ACPL_7111 ACPL_7111 rpoT rpoT ACPL_7117 ACPL_7117 ACPL_7118 ACPL_7118 ACPL_7119 ACPL_7119 indA indA ACPL_7121 ACPL_7121 sigB sigB ACPL_7157 ACPL_7157 dinF dinF ACPL_7246 ACPL_7246 whiB-2 whiB-2 ACPL_7563 ACPL_7563 ACPL_7567 ACPL_7567 ACPL_7568 ACPL_7568 ACPL_7569 ACPL_7569 whiB-3 whiB-3 ACPL_7571 ACPL_7571 ACPL_7599 ACPL_7599 ACPL_7600 ACPL_7600 ACPL_7601 ACPL_7601 whiB-4 whiB-4 ACPL_764 ACPL_764 ACPL_765 ACPL_765 ACPL_7801 ACPL_7801 ACPL_7836 ACPL_7836 ACPL_7837 ACPL_7837 ACPL_7838 ACPL_7838 ACPL_7839 ACPL_7839 ACPL_7993 ACPL_7993 ACPL_8004 ACPL_8004 ACPL_8005 ACPL_8005 ACPL_8038 ACPL_8038 lsr2-2 lsr2-2 whiB-5 whiB-5 ACPL_8117 ACPL_8117 ACPL_8118 ACPL_8118 ACPL_8247 ACPL_8247
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
whiBTranscription factor WhiB; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA. (85 aa)
ACPL_1052Uncharacterized protein conserved in bacteria. (168 aa)
ACPL_1053Hypothetical protein. (102 aa)
ACPL_120Uncharacterized protein; Zn-ribbon-containing, possibly RNA-binding protein and truncated derivatives. (172 aa)
ACPL_125Uncharacterized protein. (244 aa)
hrdBRNA polymerase principal sigma factor hrdB; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (333 aa)
ACPL_1401Hypothetical protein. (282 aa)
ACPL_1403Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. (400 aa)
ACPL_1507Multidrug-efflux transporter 1 regulator; Predicted transcriptional regulators. (285 aa)
ACPL_1519Hypothetical protein. (163 aa)
ACPL_1526Uncharacterized protein; Regulator of polyketide synthase expression. (362 aa)
ACPL_1529Hypothetical protein. (216 aa)
ACPL_1532Uncharacterized protein. (134 aa)
ACPL_1534Uncharacterized protein. (143 aa)
ahpEAlkyl hydroperoxide reductase/thiol specific antioxidant/Mal allergen; Peroxiredoxin. (154 aa)
ACPL_1536Hypothetical protein. (246 aa)
ACPL_1579RDD domain-containing protein. (133 aa)
ACPL_1606Uncharacterized protein. (230 aa)
ACPL_1633Uncharacterized protein. (206 aa)
ACPL_1647Predicted membrane protein. (323 aa)
ACPL_1744Hypothetical protein. (130 aa)
ACPL_1818Response regulator with putative antiterminator output domain. (206 aa)
ACPL_1849Cytochrome b6-f complex iron-sulfur subunit; Rieske Fe-S protein. (182 aa)
ACPL_1851Hypothetical protein; Displays ATPase and GTPase activities. (304 aa)
ACPL_1852Uncharacterized protein; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family. (361 aa)
whiAHypothetical protein; Involved in cell division and chromosome segregation. (326 aa)
rbpAElectron transport protein; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters. (113 aa)
ACPL_1926Hypothetical protein. (267 aa)
ACPL_235Hypothetical protein. (120 aa)
ACPL_240Hypothetical protein. (72 aa)
ACPL_2405Universal stress protein UspA and related nucleotide-binding proteins. (291 aa)
ACPL_2408Predicted transcriptional regulators. (143 aa)
rbpA-2Hypothetical protein; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters. Belongs to the RNA polymerase-binding protein RbpA family. (112 aa)
ACPL_285Putative transposase. (774 aa)
ACPL_3016Hypothetical protein. (247 aa)
ACPL_3836Multidrug-efflux transporter 1 regulator; Predicted transcriptional regulators. (257 aa)
ACPL_4659Dolichyl-phosphate-mannose-protein O-mannosyl transferase. (480 aa)
ACPL_4757Hypothetical protein; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases. (106 aa)
ACPL_4758Hypothetical protein; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases. (98 aa)
ACPL_5070Predicted transcriptional regulators. (182 aa)
ACPL_5224Hypothetical protein. (64 aa)
ACPL_5228Hypothetical protein. (80 aa)
pafCProteasome accessory factor C; Predicted transcriptional regulator. (328 aa)
pafBProteasome accessory factor B; Predicted transcriptional regulator. (322 aa)
ACPL_5231Zinc transporter 9; Co/Zn/Cd efflux system component. (335 aa)
ACPL_5232Hypothetical protein. (359 aa)
ACPL_538Uncharacterized protein. (273 aa)
gylRHTH-type transcriptional repressor allR; Transcriptional regulator. (251 aa)
ACPL_5929Hypothetical protein. (340 aa)
ogt-2UDP-N-acetylglucosamine-peptide N-acetylglucosaminyltransferase 110 kDa subunit; FOG: TPR repeat. (346 aa)
ACPL_6657Protein lsr2. (115 aa)
ACPL_6658Hypothetical protein. (143 aa)
lsr2Protein lsr2. (115 aa)
ACPL_7087Hypothetical protein. (176 aa)
ACPL_7101Hypothetical protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (427 aa)
ACPL_7102Inner membrane transport protein yeeF; Amino acid transporters. (680 aa)
trkATrk system potassium uptake protein trkA; K+ transport systems, NAD-binding component. (221 aa)
trkA-2TrkA-like trk system potassium uptake protein; K+ transport systems, NAD-binding component. (221 aa)
ACPL_7105Hypothetical protein. (253 aa)
ACPL_7106Hypothetical protein. (125 aa)
ACPL_7107Hypothetical protein. (215 aa)
ACPL_7109Hypothetical protein. (170 aa)
ACPL_7111Hypothetical protein. (98 aa)
rpoTRNA polymerase sigma factor rpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (528 aa)
ACPL_7117Uncharacterized protein; DNA or RNA helicases of superfamily II. (576 aa)
ACPL_7118Predicted membrane protein. (204 aa)
ACPL_7119Hypothetical protein. (72 aa)
indAIndigoidine synthase A family protein; Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway; Belongs to the pseudouridine-5'-phosphate glycosidase family. (319 aa)
ACPL_7121Bifunctional protein hldE; Sugar kinases, ribokinase family. (298 aa)
sigBRNA polymerase principal sigma factor hrdB; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (329 aa)
ACPL_7157Hypothetical protein. (403 aa)
dinFMultidrug resistance protein mdtK; Na+-driven multidrug efflux pump. (437 aa)
ACPL_7246Hypothetical protein; Predicted acetyltransferase. (279 aa)
whiB-2Transcription factor WhiB; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA. (84 aa)
ACPL_7563Signal transduction histidine kinase. (512 aa)
ACPL_7567Anti-sigma factor. (94 aa)
ACPL_7568DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (272 aa)
ACPL_7569Hypothetical protein; Predicted hydrolase of the alpha/beta-hydrolase fold. (204 aa)
whiB-3Transcription factor WhiB; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA. (132 aa)
ACPL_7571yoqW-like uncharacterized protein; Belongs to the SOS response-associated peptidase family. (225 aa)
ACPL_7599Uncharacterized protein. (999 aa)
ACPL_7600Predicted secreted protein containing a PDZ domain. (343 aa)
ACPL_7601Hypothetical protein. (431 aa)
whiB-4Transcriptional regulatory protein WhiB-like WhiB7; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA. (120 aa)
ACPL_764Uncharacterized protein; Acyl dehydratase; Belongs to the UPF0336 family. (166 aa)
ACPL_765Peroxisomal multifunctional enzyme type 2; Acyl dehydratase. (131 aa)
ACPL_7801Dolichyl-phosphate-mannose-protein O-mannosyl transferase. (523 aa)
ACPL_7836Putative epimerase; PhzC/PhzF homolog. (293 aa)
ACPL_7837Mg/Co/Ni transporter MgtE (contains CBS domain). (422 aa)
ACPL_7838Predicted membrane protein. (173 aa)
ACPL_7839Mrp-like protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (382 aa)
ACPL_7993Hypothetical protein. (107 aa)
ACPL_8004Predicted Zn-dependent hydrolases of the beta-lactamase fold. (214 aa)
ACPL_8005Multiple antibiotic resistance protein marR; Transcriptional regulators. (145 aa)
ACPL_8038Transcriptional regulators, similar to M. xanthus CarD. (161 aa)
lsr2-2Protein lsr2. (118 aa)
whiB-5Transcription factor WhiB; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA. (100 aa)
ACPL_8117Hypothetical protein. (150 aa)
ACPL_8118Putative metallophosphoesterase; Predicted phosphohydrolases. (297 aa)
ACPL_8247Abortive infection protein; Predicted metal-dependent membrane protease. (257 aa)
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.