(60 nodes) Lipid catabolic process network (Actinoplanes sp. SE50110)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	fadE	Acyl-CoA dehydrogenases. (382 aa)
	ACPL_2200	Platelet-activating factor acetylhydrolase; Predicted dienelactone hydrolase. (416 aa)
	ACPL_2175	Similar to mitochondrial Short-chain specific acyl-CoA dehydrogenase; Acyl-CoA dehydrogenases. (391 aa)
	ACPL_2126	Acyl-CoA dehydrogenases. (555 aa)
	ACPL_2124	Lysophospholipase NTE1; Predicted esterase of the alpha-beta hydrolase superfamily. (271 aa)
	ACPL_183	Acyl-CoA dehydrogenases. (618 aa)
	ACPL_1615	Uncharacterized protein; Predicted nucleoside-diphosphate sugar epimerase. (307 aa)
	acdH	Acyl-CoA dehydrogenases. (385 aa)
	fadE-5	Acyl-CoA dehydrogenases. (383 aa)
	ACPL_948	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (414 aa)
	ACPL_7667	Acyl-CoA dehydrogenases. (401 aa)
	lip	Triacylglycerol lipase; Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold. (273 aa)
	ACPL_7536	Patatin-like phospholipase domain-containing protein; Predicted esterase of the alpha-beta hydrolase superfamily. (286 aa)
	ACPL_7418	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa)
	fadB-2	3-hydroxyacyl-CoA dehydrogenase. (687 aa)
	ACPL_7090	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (398 aa)
	choD-2	Cholesterol oxidase; Choline dehydrogenase and related flavoproteins. (546 aa)
	ACPL_7021	Acyl-CoA dehydrogenases. (568 aa)
	gcdH	Acyl-CoA dehydrogenases. (388 aa)
	ACPL_6734	Secreted hydrolase; Lysophospholipase L1 and related esterases. (260 aa)
	ACPL_673	Secreted protein. (897 aa)
	ACPL_6410	Platelet-activating factor acetylhydrolase; Predicted dienelactone hydrolase. (298 aa)
	acd-3	Acyl-CoA dehydrogenases. (395 aa)
	fadE-4	Acyl-CoA dehydrogenases. (383 aa)
	ACPL_5702	Lipase, class 2; Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold. (291 aa)
	ACPL_5622	Secreted hydrolase. (258 aa)
	ACPL_5589	Carotenoid cleavage dioxygenase; Lignostilbene-alpha,beta-dioxygenase and related enzymes. (447 aa)
	ACPL_5569	Acyl-CoA dehydrogenases. (657 aa)
	prpB	Methylisocitrate lyase; PEP phosphonomutase and related enzymes. (307 aa)
	ACPL_555	Acyl-CoA dehydrogenases. (391 aa)
	choD	Cholesterol oxidase; Choline dehydrogenase and related flavoproteins. (558 aa)
	ACPL_5508	Acyl-CoA dehydrogenases. (403 aa)
	ACPL_5497	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (425 aa)
	ACPL_5471	Sphingomyelin phosphodiesterase 2. (425 aa)
	ACPL_5170	Acyl-CoA dehydrogenases. (534 aa)
	acd-2	Acyl-CoA dehydrogenases. (399 aa)
	ACPL_4679	Acyl-CoA dehydrogenase. (641 aa)
	ACPL_4367	tRNA uridine 5-carboxymethylaminomethyl modification enzyme mnmG; Predicted oxidoreductase. (556 aa)
	ACPL_4285	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (389 aa)
	ACPL_4053	Lysophospholipase NTE1; Predicted esterase of the alpha-beta hydrolase superfamily. (278 aa)
	ACPL_3814	Platelet-activating factor acetylhydrolase 2, cytoplasmic; Predicted dienelactone hydrolase. (388 aa)
	ACPL_3794	Hypothetical protein. (231 aa)
	ACPL_3591	Similar to mitochondrial Short-chain specific acyl-CoA dehydrogenase; Acyl-CoA dehydrogenases. (396 aa)
	ACPL_3590	Similar to mitochondrial Short-chain specific acyl-CoA dehydrogenase; Acyl-CoA dehydrogenases. (402 aa)
	estA-2	Esterase; Lysophospholipase L1 and related esterases. (420 aa)
	ACPL_3291	Platelet-activating factor acetylhydrolase; Predicted dienelactone hydrolase. (385 aa)
	ACPL_3240	Hypothetical protein; Hydrolases of the alpha/beta superfamily. (259 aa)
	ACPL_3158	Acyl-CoA dehydrogenases. (380 aa)
	ACPL_3155	Hypothetical protein. (630 aa)
	lip1	Triacylglycerol lipase. (445 aa)
	ACPL_2935	Triacylglycerol lipase; Dienelactone hydrolase and related enzymes. (291 aa)
	ACPL_3073	Collagen alpha-5(VI) chain; Predicted dienelactone hydrolase. (474 aa)
	paaK	Phenylacetic acid degradation NADH oxidoreductase; Flavodoxin reductases (ferredoxin-NADPH reductases) family 1. (348 aa)
	ACPL_2825	Hypothetical protein; Acyl-CoA dehydrogenases. (393 aa)
	acd	Acyl-CoA dehydrogenases. (377 aa)
	pcaF	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (391 aa)
	fadE-3	Acyl-CoA dehydrogenases. (390 aa)
	fadA	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (410 aa)
	fadB	3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase; 3-hydroxyacyl-CoA dehydrogenase. (676 aa)
	fadE-2	Acyl-CoA dehydrogenases. (385 aa)

Your Current Organism:

Actinoplanes sp. SE50110

NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACPL_183	fadA	ACPL_183	ACPL_2501	Acyl-CoA dehydrogenases.	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.484
ACPL_183	fadB	ACPL_183	ACPL_2500	Acyl-CoA dehydrogenases.	3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase; 3-hydroxyacyl-CoA dehydrogenase.	0.876
ACPL_183	fadB-2	ACPL_183	ACPL_7091	Acyl-CoA dehydrogenases.	3-hydroxyacyl-CoA dehydrogenase.	0.864
ACPL_2124	ACPL_2126	ACPL_2124	ACPL_2126	Lysophospholipase NTE1; Predicted esterase of the alpha-beta hydrolase superfamily.	Acyl-CoA dehydrogenases.	0.676
ACPL_2126	ACPL_2124	ACPL_2126	ACPL_2124	Acyl-CoA dehydrogenases.	Lysophospholipase NTE1; Predicted esterase of the alpha-beta hydrolase superfamily.	0.676
ACPL_2126	ACPL_4285	ACPL_2126	ACPL_4285	Acyl-CoA dehydrogenases.	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.936
ACPL_2126	ACPL_5497	ACPL_2126	ACPL_5497	Acyl-CoA dehydrogenases.	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.777
ACPL_2126	ACPL_555	ACPL_2126	ACPL_555	Acyl-CoA dehydrogenases.	Acyl-CoA dehydrogenases.	0.900
ACPL_2126	ACPL_5569	ACPL_2126	ACPL_5569	Acyl-CoA dehydrogenases.	Acyl-CoA dehydrogenases.	0.900
ACPL_2126	ACPL_7090	ACPL_2126	ACPL_7090	Acyl-CoA dehydrogenases.	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.936
ACPL_2126	ACPL_7418	ACPL_2126	ACPL_7418	Acyl-CoA dehydrogenases.	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.777
ACPL_2126	ACPL_7667	ACPL_2126	ACPL_7667	Acyl-CoA dehydrogenases.	Acyl-CoA dehydrogenases.	0.900
ACPL_2126	ACPL_948	ACPL_2126	ACPL_948	Acyl-CoA dehydrogenases.	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.777
ACPL_2126	acd-3	ACPL_2126	ACPL_6241	Acyl-CoA dehydrogenases.	Acyl-CoA dehydrogenases.	0.921
ACPL_2126	fadA	ACPL_2126	ACPL_2501	Acyl-CoA dehydrogenases.	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.777
ACPL_2126	fadB	ACPL_2126	ACPL_2500	Acyl-CoA dehydrogenases.	3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase; 3-hydroxyacyl-CoA dehydrogenase.	0.982
ACPL_2126	fadB-2	ACPL_2126	ACPL_7091	Acyl-CoA dehydrogenases.	3-hydroxyacyl-CoA dehydrogenase.	0.832
ACPL_2126	fadE-2	ACPL_2126	ACPL_2420	Acyl-CoA dehydrogenases.	Acyl-CoA dehydrogenases.	0.919
ACPL_2126	fadE-3	ACPL_2126	ACPL_2502	Acyl-CoA dehydrogenases.	Acyl-CoA dehydrogenases.	0.919
ACPL_2126	fadE-4	ACPL_2126	ACPL_5740	Acyl-CoA dehydrogenases.	Acyl-CoA dehydrogenases.	0.920