STRINGSTRING
ddl ddl ACPL_7345 ACPL_7345 ACPL_7362 ACPL_7362 ACPL_7393 ACPL_7393 murA-2 murA-2 ACPL_7444 ACPL_7444 ACPL_7463 ACPL_7463 prfA prfA ACPL_7569 ACPL_7569 ACPL_7592 ACPL_7592 ACPL_7611 ACPL_7611 ACPL_7625 ACPL_7625 ACPL_7626 ACPL_7626 ACPL_7717 ACPL_7717 glmU glmU ACPL_7839 ACPL_7839 csrA csrA yviF yviF flgK flgK fliS fliS ACPL_7910 ACPL_7910 pclO-2 pclO-2 flhA flhA paaD paaD fliP fliP ACPL_7919 ACPL_7919 flgD flgD murB murB dinG dinG ACPL_8026 ACPL_8026 ACPL_8033 ACPL_8033 ACPL_8175 ACPL_8175 ACPL_8183 ACPL_8183 ACPL_8242 ACPL_8242 ACPL_8245 ACPL_8245 ACPL_8279 ACPL_8279 ACPL_8294 ACPL_8294 ACPL_8300 ACPL_8300 ACPL_8324 ACPL_8324 dnaB-3 dnaB-3 ACPL_8357 ACPL_8357 ddlA ddlA ACPL_8382 ACPL_8382 ACPL_872 ACPL_872 pcrA-2 pcrA-2 trcF trcF ACPL_929 ACPL_929 ACPL_936 ACPL_936 ACPL_7917 ACPL_7917 ACPL_3130 ACPL_3130 ybhC ybhC ACPL_3180 ACPL_3180 ACPL_3233 ACPL_3233 ACPL_3235 ACPL_3235 uppP uppP ACPL_3320 ACPL_3320 ACPL_3321 ACPL_3321 ACPL_3392 ACPL_3392 ACPL_3438 ACPL_3438 ACPL_3698 ACPL_3698 ACPL_3743 ACPL_3743 ccdA ccdA resB resB ccsA ccsA ddx5 ddx5 fliQ-2 fliQ-2 uppP-2 uppP-2 ACPL_432 ACPL_432 ACPL_438 ACPL_438 ACPL_4510 ACPL_4510 ACPL_4545 ACPL_4545 ACPL_4628 ACPL_4628 ACPL_4829 ACPL_4829 ACPL_484 ACPL_484 ACPL_4878 ACPL_4878 ACPL_4895 ACPL_4895 topA topA mraY-2 mraY-2 ACPL_5019 ACPL_5019 dacC dacC ACPL_5196 ACPL_5196 ACPL_526 ACPL_526 ACPL_5319 ACPL_5319 ACPL_5344 ACPL_5344 ACPL_5371 ACPL_5371 ACPL_5433 ACPL_5433 recD recD ACPL_5570 ACPL_5570 ACPL_5618 ACPL_5618 ACPL_5719 ACPL_5719 deaD deaD ACPL_5793 ACPL_5793 dnaB dnaB ACPL_5832 ACPL_5832 ACPL_584 ACPL_584 ACPL_5895 ACPL_5895 ACPL_5928 ACPL_5928 ACPL_5941 ACPL_5941 ACPL_5944 ACPL_5944 pks3A pks3A prfH prfH ACPL_6350 ACPL_6350 ACPL_6388 ACPL_6388 argR argR rplT rplT priA priA mltG mltG mltG-2 mltG-2 ACPL_6494 ACPL_6494 cphA cphA ruvB ruvB ruvA ruvA ACPL_6544 ACPL_6544 fusA-2 fusA-2 ACPL_6585 ACPL_6585 dac dac ACPL_6663 ACPL_6663 ACPL_6666 ACPL_6666 gyrA-2 gyrA-2 gyrB-2 gyrB-2 ACPL_6695 ACPL_6695 ACPL_670 ACPL_670 ACPL_6765 ACPL_6765 ssgB ssgB ACPL_6925 ACPL_6925 ACPL_7030 ACPL_7030 ACPL_7048 ACPL_7048 ACPL_7062 ACPL_7062 ACPL_7096 ACPL_7096 ACPL_7097 ACPL_7097 ACPL_7106 ACPL_7106 ACPL_7157 ACPL_7157 ACPL_717 ACPL_717 frr frr ACPL_7263 ACPL_7263 ACPL_7280 ACPL_7280 ACPL_7297 ACPL_7297 smc smc recG recG helZ helZ ACPL_2879 ACPL_2879 ACPL_2717 ACPL_2717 ACPL_2674 ACPL_2674 fliQ fliQ ACPL_2508 ACPL_2508 ACPL_2506 ACPL_2506 ACPL_2097 ACPL_2097 ACPL_2094 ACPL_2094 ACPL_2049 ACPL_2049 ACPL_2029 ACPL_2029 murD murD ACPL_1937 ACPL_1937 ACPL_1877 ACPL_1877 iscU iscU ACPL_1872 ACPL_1872 sufB sufB typA typA ACPL_1774 ACPL_1774 sepF sepF ftsZ ftsZ ftsQ ftsQ murC murC murG murG mraY mraY murF murF murE murE ACPL_1751 ACPL_1751 ACPL_1750 ACPL_1750 ACPL_1641 ACPL_1641 pbpA pbpA ACPL_1637 ACPL_1637 murA murA ACPL_1612 ACPL_1612 ACPL_1537 ACPL_1537 ACPL_1515 ACPL_1515 pcrA pcrA rsfS rsfS sufE sufE gyrA gyrA gyrB gyrB ACPL_1188 ACPL_1188 pilT pilT ACPL_1123 ACPL_1123 ACPL_1122 ACPL_1122 prfB prfB ACPL_1049 ACPL_1049 triO triO ACPL_1017 ACPL_1017
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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co-expression
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ddlD-alanyl-alanine synthetase A; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (367 aa)
ACPL_7345Integration host factor subunit beta; Bacterial nucleoid DNA-binding protein; Belongs to the bacterial histone-like protein family. (276 aa)
ACPL_7362Protein chain release factor B. (140 aa)
ACPL_7393Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes. (391 aa)
murA-2UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (439 aa)
ACPL_7444Cell envelope-related transcriptional attenuator; Transcriptional regulator. (373 aa)
ACPL_7463Hypothetical protein. (442 aa)
prfAPeptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. (362 aa)
ACPL_7569Hypothetical protein; Predicted hydrolase of the alpha/beta-hydrolase fold. (204 aa)
ACPL_7592Membrane-bound protein lytR; Transcriptional regulator. (394 aa)
ACPL_7611Superfamily I DNA and RNA helicases. (708 aa)
ACPL_7625Superfamily I DNA and RNA helicases; Belongs to the helicase family. UvrD subfamily. (1221 aa)
ACPL_7626Superfamily I DNA and RNA helicases; Belongs to the helicase family. UvrD subfamily. (1354 aa)
ACPL_7717Halomucin; Type V secretory pathway, adhesin AidA. (467 aa)
glmUBifunctional protein GlmU; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (461 aa)
ACPL_7839Mrp-like protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (382 aa)
csrACarbon storage regulator; A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'- UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW. (79 aa)
yviFFlagellar assembly factor FliW; Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum. (145 aa)
flgKFlagellar hook-associated protein; Belongs to the flagella basal body rod proteins family. (486 aa)
fliSFlagellar protein fliS; Flagellin-specific chaperone FliS. (124 aa)
ACPL_7910TolA family protein. (156 aa)
pclO-2Protein piccolo; Type V secretory pathway, adhesin AidA. (537 aa)
flhAFlagellar biosynthesis protein flhA; Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family. (680 aa)
paaDPhenylacetic acid degradation protein paaD; Predicted metal-sulfur cluster biosynthetic enzyme. (162 aa)
fliPFlagellar biosynthetic protein FliP; Plays a role in the flagellum-specific transport system. Belongs to the FliP/MopC/SpaP family. (290 aa)
ACPL_7919Flagellar protein FliO/FliZ. (142 aa)
flgDBasal-body rod modification protein flgD; Flagellar hook capping protein. (148 aa)
murBUDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (358 aa)
dinGRad3-related DNA helicases. (632 aa)
ACPL_8026Hypothetical protein. (425 aa)
ACPL_8033Serine/threonine-protein kinase afsK. (374 aa)
ACPL_8175Uncharacterized protein; FOG: WD40-like repeat. (353 aa)
ACPL_8183Hypothetical protein; Peptide chain release factor 1 (eRF1). (338 aa)
ACPL_8242NFX1-type zinc finger-containing protein 1; Superfamily I DNA and RNA helicases and helicase subunits. (902 aa)
ACPL_8245Nuclease sbcCD subunit C; ATPase components of ABC transporters with duplicated ATPase domains. (874 aa)
ACPL_8279Two-component system, LytT family, sensor kinase; Putative regulator of cell autolysis. (397 aa)
ACPL_8294Membrane-bound protein lytR; Transcriptional regulator. (366 aa)
ACPL_8300Hypothetical protein. (193 aa)
ACPL_8324Superfamily I DNA and RNA helicases. (1038 aa)
dnaB-3Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (427 aa)
ACPL_8357Capsule biosynthesis protein capC. (161 aa)
ddlAD-alanine-D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (320 aa)
ACPL_8382Protein jag; Predicted RNA-binding protein. (195 aa)
ACPL_872Membrane-bound protein lytR; Transcriptional regulator. (354 aa)
pcrA-2Superfamily I DNA and RNA helicases. (865 aa)
trcFTranscription-repair coupling factor (superfamily II helicase); Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. (1203 aa)
ACPL_929Nucleoside-triphosphate pyrophosphatase; Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain. (319 aa)
ACPL_936Amino-acid N-acetyltransferase; N-acetylglutamate synthase and related acetyltransferases. (164 aa)
ACPL_7917Flagellar biosynthesis pathway, component FliR. (254 aa)
ACPL_3130Acyl-[acyl-carrier-protein]-UDP-N- acetylglucosamine O-acyltransferase; Acetyltransferase (isoleucine patch superfamily). (199 aa)
ybhCPutative pectinesterase; Pectin methylesterase. (396 aa)
ACPL_3180Hypothetical protein. (286 aa)
ACPL_3233Misshapen-like kinase 1. (886 aa)
ACPL_3235Hypothetical protein. (629 aa)
uppPUndecaprenyl-diphosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. (329 aa)
ACPL_3320Uncharacterized protein conserved in bacteria. (743 aa)
ACPL_3321Tetratricopeptide repeat protein 28; FOG: TPR repeat. (915 aa)
ACPL_3392Microtubule-associated protein 1A; Uncharacterized protein conserved in bacteria with the myosin-like domain. (106 aa)
ACPL_3438Beta-galactoside-specific lectin 3. (496 aa)
ACPL_3698Adenylate cyclase, class 2. (193 aa)
ACPL_3743Membrane protein ydfJ; Predicted drug exporters of the RND superfamily. (922 aa)
ccdACytochrome c biogenesis protein. (262 aa)
resBResB protein required for cytochrome c biosynthesis. (535 aa)
ccsAABC-type transport system involved in cytochrome c biogenesis, permease component. (324 aa)
ddx5DEAD/DEAH box helicase domain-containing protein; Superfamily II DNA and RNA helicases. (659 aa)
fliQ-2Flagellar biosynthetic protein fliQ; Role in flagellar biosynthesis. Belongs to the FliQ/MopD/SpaQ family. (89 aa)
uppP-2Undecaprenyl-diphosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. (270 aa)
ACPL_432Helicase IV; Superfamily I DNA and RNA helicases. (668 aa)
ACPL_438Non-specific serine/threonine protein kinase; Superfamily II DNA/RNA helicases, SNF2 family. (1016 aa)
ACPL_4510Hypothetical protein. (514 aa)
ACPL_4545Methyl-accepting chemotaxis protein 3; Type V secretory pathway, adhesin AidA. (1058 aa)
ACPL_4628Hypothetical protein. (164 aa)
ACPL_4829Hypothetical protein. (323 aa)
ACPL_484Putative ATP-dependent helicase HRQ1; Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster. (850 aa)
ACPL_4878Hypothetical protein. (326 aa)
ACPL_4895Tetratricopeptide repeat protein 28; Uncharacterized protein conserved in bacteria. (892 aa)
topADNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] (926 aa)
mraY-2phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (367 aa)
ACPL_5019Pectinesterase; Pectin methylesterase. (328 aa)
dacCD-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5/6); D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family. (377 aa)
ACPL_5196Membrane-bound protein lytR; Transcriptional regulator. (369 aa)
ACPL_526DNA excision repair protein ERCC-3; DNA or RNA helicases of superfamily II. (548 aa)
ACPL_5319Membrane-bound protein lytR; Transcriptional regulator. (359 aa)
ACPL_5344Hypothetical protein. (234 aa)
ACPL_5371Polycystic kidney disease protein 1-like 3; Predicted drug exporters of the RND superfamily. (714 aa)
ACPL_5433Putative membrane protein mmpL3; Predicted drug exporters of the RND superfamily. (717 aa)
recDExodeoxyribonuclease V alpha subunit; DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity; Belongs to the RecD family. RecD-like subfamily. (732 aa)
ACPL_5570Predicted integral membrane protein. (229 aa)
ACPL_5618Cell surface glycoprotein 1; Predicted drug exporters of the RND superfamily. (295 aa)
ACPL_5719Pectinesterase; Pectin methylesterase. (322 aa)
deaDCold-shock DEAD box protein A; Superfamily II DNA and RNA helicases; Belongs to the DEAD box helicase family. (569 aa)
ACPL_5793Hypothetical protein. (355 aa)
dnaBReplicative DNA helicase. (84 aa)
ACPL_5832Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (351 aa)
ACPL_584Membrane protein ydfJ; Predicted drug exporters of the RND superfamily. (739 aa)
ACPL_5895Hypothetical protein. (230 aa)
ACPL_5928F-box DNA helicase protein 1; DNA methylase. (5399 aa)
ACPL_5941Hypothetical protein. (355 aa)
ACPL_5944Putative mobilization relaxase component. (475 aa)
pks3APolyketide synthase modules and related proteins. (756 aa)
prfHProtein chain release factor B. (164 aa)
ACPL_6350Hypothetical protein. (275 aa)
ACPL_6388Helicase IV; Superfamily I DNA and RNA helicases. (777 aa)
argRArginine repressor; Regulates arginine biosynthesis genes. (167 aa)
rplT50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. (130 aa)
priAPrimosomal protein N' (replication factor Y) (superfamily II helicase); Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (734 aa)
mltGHypothetical protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family. (395 aa)
mltG-2Hypothetical protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family. (393 aa)
ACPL_6494Collagen alpha-2(I) chain; Superfamily II DNA and RNA helicases. (945 aa)
cphACyanophycin synthetase; D-alanine-D-alanine ligase and related ATP-grasp enzymes. (925 aa)
ruvBHolliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (348 aa)
ruvAHolliday junction ATP-dependent DNA helicase ruvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (200 aa)
ACPL_6544Hypothetical protein. (174 aa)
fusA-2Translation elongation factors (GTPases). (719 aa)
ACPL_6585Hypothetical protein. (132 aa)
dacD-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5/6); D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family. (412 aa)
ACPL_6663Helicase IV; Superfamily I DNA and RNA helicases. (766 aa)
ACPL_6666Pre-mRNA-processing ATP-dependent RNA helicase PRP5; Superfamily II DNA and RNA helicases. (591 aa)
gyrA-2Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit. (841 aa)
gyrB-2Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit. (685 aa)
ACPL_6695Zinc finger SWIM domain protein. (937 aa)
ACPL_670Membrane protein ydfJ; Predicted drug exporters of the RND superfamily. (853 aa)
ACPL_6765Hypothetical protein; Predicted NTPase (NACHT family). (672 aa)
ssgBSporulation and cell division protein SsgA. (143 aa)
ACPL_6925Hypothetical protein. (515 aa)
ACPL_7030Putative membrane protein mmpL11; Predicted drug exporters of the RND superfamily. (746 aa)
ACPL_7048Hypothetical protein; Predicted ATPase. (581 aa)
ACPL_7062Hypothetical protein. (192 aa)
ACPL_7096Hypothetical protein. (449 aa)
ACPL_7097Hypothetical protein. (435 aa)
ACPL_7106Hypothetical protein. (125 aa)
ACPL_7157Hypothetical protein. (403 aa)
ACPL_717Pre-mRNA-processing ATP-dependent RNA helicase PRP5; Superfamily II DNA and RNA helicases; Belongs to the DEAD box helicase family. (648 aa)
frrRibosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. (185 aa)
ACPL_7263Uncharacterized protein; Predicted ATPase with chaperone activity. (511 aa)
ACPL_7280Predicted RNA-binding protein (contains KH domain); Belongs to the UPF0109 family. (85 aa)
ACPL_7297UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase. (731 aa)
smcChromosome partition protein smc; Required for chromosome condensation and partitioning. Belongs to the SMC family. (1193 aa)
recGRecG-like helicase. (726 aa)
helZHelicase HelZ; Superfamily II DNA/RNA helicases, SNF2 family. (1132 aa)
ACPL_2879Putative membrane protein mmpL3; Predicted drug exporters of the RND superfamily. (1820 aa)
ACPL_2717Topoisomerase IB. (316 aa)
ACPL_2674Helicase IV; Superfamily I DNA and RNA helicases. (688 aa)
fliQFlagellar biosynthetic protein fliQ; Role in flagellar biosynthesis. Belongs to the FliQ/MopD/SpaQ family. (89 aa)
ACPL_2508Tetratricopeptide repeat protein 28; Uncharacterized protein conserved in bacteria. (1282 aa)
ACPL_2506Putative ATP-dependent DNA helicase yjcD; Superfamily I DNA and RNA helicases. (553 aa)
ACPL_2097Hypothetical protein. (228 aa)
ACPL_2094Transcription-repair coupling factor (superfamily II helicase). (203 aa)
ACPL_2049Cell envelope-related transcriptional attenuator; Transcriptional regulator. (385 aa)
ACPL_2029Uncharacterized protein conserved in bacteria. (645 aa)
murDUDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (447 aa)
ACPL_1937Hypothetical protein. (432 aa)
ACPL_1877yitW-like uncharacterized protein; Predicted metal-sulfur cluster biosynthetic enzyme. (265 aa)
iscUSimilar to mitochondrial Iron sulfur cluster assembly protein 1; NifU homolog involved in Fe-S cluster formation. (151 aa)
ACPL_1872Uncharacterized protein; ABC-type transport system involved in Fe-S cluster assembly, permease component. (373 aa)
sufBABC-type transport system involved in Fe-S cluster assembly, permease component. (473 aa)
typAGTP-binding protein lepA; Predicted membrane GTPase involved in stress response. (623 aa)
ACPL_1774Hypothetical protein. (332 aa)
sepFCell division protein sepF; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA. (245 aa)
ftsZCell division protein ftsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (379 aa)
ftsQFtsQ-like cell division protein; Essential cell division protein. (255 aa)
murCUDP-N-acetylmuramate-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (479 aa)
murGUndecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (368 aa)
mraYphospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (371 aa)
murFUDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate- -D-alanyl-D-alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (463 aa)
murEUDP-N-acetylmuramoylalanyl-D-glutamate-2,6- diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (500 aa)
ACPL_1751UDP-N-acetylmuramate-L-alanine ligase; UDP-N-acetylmuramyl tripeptide synthase. (406 aa)
ACPL_1750Cobyric acid synthase; Predicted glutamine amidotransferase. (237 aa)
ACPL_1641Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes. (378 aa)
pbpAPeptidoglycan glycosyltransferase; Cell division protein FtsI/penicillin-binding protein 2. (499 aa)
ACPL_1637Putative iron-sulfur cluster insertion protein erpA; Belongs to the HesB/IscA family. (122 aa)
murAUDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (451 aa)
ACPL_1612Lipoprotein yfgL; FOG: WD40-like repeat. (404 aa)
ACPL_1537Hypothetical protein. (204 aa)
ACPL_1515Helicase IV; Superfamily I DNA and RNA helicases. (714 aa)
pcrASuperfamily I DNA and RNA helicases. (643 aa)
rsfSIojap-like Protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. (134 aa)
sufESufE protein probably involved in Fe-S center assembly. (139 aa)
gyrADNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (837 aa)
gyrBDNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (650 aa)
ACPL_1188DoxX family protein. (161 aa)
pilTTwitching motility protein; Tfp pilus assembly protein, pilus retraction ATPase PilT. (373 aa)
ACPL_1123Hypothetical protein. (227 aa)
ACPL_1122Hypothetical protein. (193 aa)
prfBPeptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. (370 aa)
ACPL_1049Protein piccolo; DNA segregation ATPase FtsK/SpoIIIE and related proteins. (286 aa)
triOTriple functional domain protein; Type V secretory pathway, adhesin AidA. (414 aa)
ACPL_1017Putative membrane protein mmpL11; Predicted drug exporters of the RND superfamily. (746 aa)
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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