(9 nodes) Signal transduction histidine kinase, phosphotransfer (Hpt) domain network (Actinoplanes sp. SE50110)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ACPL_2318	Signal transduction histidine kinase. (825 aa)
	barA	Sensory box histidine kinase/response regulator; Signal transduction histidine kinase. (1418 aa)
	ACPL_7936	Two-component system, chemotaxis family, sensor kinase CheA; Chemotaxis protein histidine kinase and related kinases. (784 aa)
	ACPL_2274	Two-component system, cell cycle sensor kinase and response regulator; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (525 aa)
	cheA	Two-component system, chemotaxis family, sensor kinase CheA; Chemotaxis protein histidine kinase and related kinases. (788 aa)
	ACPL_5140	Two-component system, chemotaxis family, sensor kinase CheA; Chemotaxis protein histidine kinase and related kinases. (702 aa)
	ACPL_4809	Two-component system sensor protein; Signal transduction histidine kinase. (774 aa)
	ACPL_3534	Two-component hybrid sensor and regulator; Signal transduction histidine kinase. (902 aa)
	ACPL_2449	Hypothetical protein; FOG: HPt domain. (128 aa)

Your Current Organism:

Actinoplanes sp. SE50110

NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACPL_2274	ACPL_2318	ACPL_2274	ACPL_2318	Two-component system, cell cycle sensor kinase and response regulator; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.	Signal transduction histidine kinase.	0.992
ACPL_2274	ACPL_3534	ACPL_2274	ACPL_3534	Two-component system, cell cycle sensor kinase and response regulator; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.	Two-component hybrid sensor and regulator; Signal transduction histidine kinase.	0.984
ACPL_2274	ACPL_4809	ACPL_2274	ACPL_4809	Two-component system, cell cycle sensor kinase and response regulator; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.	Two-component system sensor protein; Signal transduction histidine kinase.	0.993
ACPL_2274	ACPL_5140	ACPL_2274	ACPL_5140	Two-component system, cell cycle sensor kinase and response regulator; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.	Two-component system, chemotaxis family, sensor kinase CheA; Chemotaxis protein histidine kinase and related kinases.	0.986
ACPL_2274	ACPL_7936	ACPL_2274	ACPL_7936	Two-component system, cell cycle sensor kinase and response regulator; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.	Two-component system, chemotaxis family, sensor kinase CheA; Chemotaxis protein histidine kinase and related kinases.	0.697
ACPL_2274	barA	ACPL_2274	ACPL_3376	Two-component system, cell cycle sensor kinase and response regulator; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.	Sensory box histidine kinase/response regulator; Signal transduction histidine kinase.	0.993
ACPL_2274	cheA	ACPL_2274	ACPL_7129	Two-component system, cell cycle sensor kinase and response regulator; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.	Two-component system, chemotaxis family, sensor kinase CheA; Chemotaxis protein histidine kinase and related kinases.	0.697
ACPL_2318	ACPL_2274	ACPL_2318	ACPL_2274	Signal transduction histidine kinase.	Two-component system, cell cycle sensor kinase and response regulator; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.	0.992
ACPL_2318	ACPL_2449	ACPL_2318	ACPL_2449	Signal transduction histidine kinase.	Hypothetical protein; FOG: HPt domain.	0.900
ACPL_2318	ACPL_3534	ACPL_2318	ACPL_3534	Signal transduction histidine kinase.	Two-component hybrid sensor and regulator; Signal transduction histidine kinase.	0.987
ACPL_2318	ACPL_4809	ACPL_2318	ACPL_4809	Signal transduction histidine kinase.	Two-component system sensor protein; Signal transduction histidine kinase.	0.993
ACPL_2318	ACPL_5140	ACPL_2318	ACPL_5140	Signal transduction histidine kinase.	Two-component system, chemotaxis family, sensor kinase CheA; Chemotaxis protein histidine kinase and related kinases.	0.986
ACPL_2318	ACPL_7936	ACPL_2318	ACPL_7936	Signal transduction histidine kinase.	Two-component system, chemotaxis family, sensor kinase CheA; Chemotaxis protein histidine kinase and related kinases.	0.799
ACPL_2318	barA	ACPL_2318	ACPL_3376	Signal transduction histidine kinase.	Sensory box histidine kinase/response regulator; Signal transduction histidine kinase.	0.993
ACPL_2318	cheA	ACPL_2318	ACPL_7129	Signal transduction histidine kinase.	Two-component system, chemotaxis family, sensor kinase CheA; Chemotaxis protein histidine kinase and related kinases.	0.799
ACPL_2449	ACPL_2318	ACPL_2449	ACPL_2318	Hypothetical protein; FOG: HPt domain.	Signal transduction histidine kinase.	0.900
ACPL_3534	ACPL_2274	ACPL_3534	ACPL_2274	Two-component hybrid sensor and regulator; Signal transduction histidine kinase.	Two-component system, cell cycle sensor kinase and response regulator; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.	0.984
ACPL_3534	ACPL_2318	ACPL_3534	ACPL_2318	Two-component hybrid sensor and regulator; Signal transduction histidine kinase.	Signal transduction histidine kinase.	0.987
ACPL_3534	ACPL_4809	ACPL_3534	ACPL_4809	Two-component hybrid sensor and regulator; Signal transduction histidine kinase.	Two-component system sensor protein; Signal transduction histidine kinase.	0.992
ACPL_3534	ACPL_5140	ACPL_3534	ACPL_5140	Two-component hybrid sensor and regulator; Signal transduction histidine kinase.	Two-component system, chemotaxis family, sensor kinase CheA; Chemotaxis protein histidine kinase and related kinases.	0.969