(14 nodes) Carbohydrate kinase PfkB network (Actinoplanes sp. SE50110)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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Known Interactions

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Predicted Interactions

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Your Input:
	frk2	Fructokinase; Sugar kinases, ribokinase family. (311 aa)
	ACPL_1513	PfkB domain protein; Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB). (316 aa)
	adoK	Sugar kinases, ribokinase family. (325 aa)
	ACPL_1792	PfkB domain protein; Sugar kinases, ribokinase family. (296 aa)
	ACPL_2415	Bifunctional protein hldE; Sugar kinases, ribokinase family. (288 aa)
	rfaE	Cytidyltransferase-like protein; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family. (664 aa)
	iolC	5-dehydro-2-deoxygluconokinase; Sugar kinases, ribokinase family. (348 aa)
	acbK	Acarbose 7-kinase; Catalyzes the phosphorylation of the alpha-glucosidase inhibitor acarbose. Phosphorylation of acarbose could be a resistance- like self-protection mechanism; Belongs to the carbohydrate kinase PfkB family. (299 aa)
	pfkB	Fructokinase; Sugar kinases, ribokinase family. (308 aa)
	ACPL_5407	PfkB domain protein; Sugar kinases, ribokinase family. (353 aa)
	ACPL_6373	Phosphofructokinase; Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); Belongs to the carbohydrate kinase PfkB family. (313 aa)
	kdgK	2-dehydro-3-deoxygluconokinase; Sugar kinases, ribokinase family. (318 aa)
	ACPL_7121	Bifunctional protein hldE; Sugar kinases, ribokinase family. (298 aa)
	rbsK	Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (297 aa)

Your Current Organism:

Actinoplanes sp. SE50110

NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACPL_1513	ACPL_6373	ACPL_1513	ACPL_6373	PfkB domain protein; Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB).	Phosphofructokinase; Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); Belongs to the carbohydrate kinase PfkB family.	0.919
ACPL_1792	acbK	ACPL_1792	ACPL_3675	PfkB domain protein; Sugar kinases, ribokinase family.	Acarbose 7-kinase; Catalyzes the phosphorylation of the alpha-glucosidase inhibitor acarbose. Phosphorylation of acarbose could be a resistance- like self-protection mechanism; Belongs to the carbohydrate kinase PfkB family.	0.914
ACPL_6373	ACPL_1513	ACPL_6373	ACPL_1513	Phosphofructokinase; Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); Belongs to the carbohydrate kinase PfkB family.	PfkB domain protein; Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB).	0.919
ACPL_7121	frk2	ACPL_7121	ACPL_1907	Bifunctional protein hldE; Sugar kinases, ribokinase family.	Fructokinase; Sugar kinases, ribokinase family.	0.526
acbK	ACPL_1792	ACPL_3675	ACPL_1792	Acarbose 7-kinase; Catalyzes the phosphorylation of the alpha-glucosidase inhibitor acarbose. Phosphorylation of acarbose could be a resistance- like self-protection mechanism; Belongs to the carbohydrate kinase PfkB family.	PfkB domain protein; Sugar kinases, ribokinase family.	0.914
frk2	ACPL_7121	ACPL_1907	ACPL_7121	Fructokinase; Sugar kinases, ribokinase family.	Bifunctional protein hldE; Sugar kinases, ribokinase family.	0.526
frk2	pfkB	ACPL_1907	ACPL_3866	Fructokinase; Sugar kinases, ribokinase family.	Fructokinase; Sugar kinases, ribokinase family.	0.926
pfkB	frk2	ACPL_3866	ACPL_1907	Fructokinase; Sugar kinases, ribokinase family.	Fructokinase; Sugar kinases, ribokinase family.	0.926