(59 nodes) PAS domain superfamily network (Actinoplanes sp. SE50110)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ACPL_5520	Putative PAS/PAC sensor protein; FOG: PAS/PAC domain. (484 aa)
	ACPL_1150	y4lL-like uncharacterized protein; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain. (552 aa)
	ACPL_1216	y4lL-like uncharacterized protein; FOG: GGDEF domain. (606 aa)
	ACPL_1370	Multi-sensor signal transduction histidine kinase; Serine phosphatase RsbU, regulator of sigma subunit. (832 aa)
	tcsA	PAS/PAC sensor hybrid histidine kinase; Signal transduction histidine kinase. (500 aa)
	ACPL_1400	Diguanylate cyclase; FOG: PAS/PAC domain. (557 aa)
	mcpA	Biofilm dispersion protein bdlA; FOG: PAS/PAC domain. (442 aa)
	phy	Putative histidine kinase, classic; Osmosensitive K+ channel histidine kinase. (728 aa)
	ACPL_2012	Putative histidine kinase, classic; Signal transduction histidine kinase. (689 aa)
	ACPL_2016	Sensor histidine kinase and response regulator of a two component complex; FOG: PAS/PAC domain. (776 aa)
	ACPL_2101	PAS/PAC sensor hybrid histidine kinase; Signal transduction histidine kinase. (659 aa)
	tcsA-2	PAS/PAC sensor hybrid histidine kinase; Signal transduction histidine kinase. (642 aa)
	ACPL_2192	Signal transduction histidine kinase. (614 aa)
	rsbU	Uncharacterized protein; Serine phosphatase RsbU, regulator of sigma subunit. (657 aa)
	ACPL_2272	Diguanylate cyclase; FOG: GAF domain. (391 aa)
	ACPL_2273	Phytochrome A type 3; Signal transduction histidine kinase. (543 aa)
	ACPL_2379	PAS/PAC sensor hybrid histidine kinase; Signal transduction histidine kinase. (787 aa)
	phoR	Sensory box histidine kinase PhoR; Signal transduction histidine kinase. (653 aa)
	ACPL_2474	Signal transduction histidine kinase. (532 aa)
	cheR	Methylase of chemotaxis methyl-accepting proteins. (616 aa)
	tcsA-3	Signal transduction histidine kinase. (606 aa)
	ACPL_2823	Signaling protein ykoW; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain. (1019 aa)
	prpF-2	Phosphoserine phosphatase rsbP; Serine phosphatase RsbU, regulator of sigma subunit. (482 aa)
	ACPL_306	Signal transduction histidine kinase. (709 aa)
	rsbU-3	Uncharacterized protein; Serine phosphatase RsbU, regulator of sigma subunit. (637 aa)
	stuC	Osmosensitive K+ channel histidine kinase. (672 aa)
	ACPL_3374	Signaling protein ykoW; FOG: GGDEF domain. (630 aa)
	barA	Sensory box histidine kinase/response regulator; Signal transduction histidine kinase. (1418 aa)
	ACPL_3378	PAS/PAC sensor hybrid histidine kinase; Signal transduction histidine kinase. (654 aa)
	cckA	Osmosensitive K+ channel histidine kinase. (779 aa)
	ACPL_3427	Two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR; Osmosensitive K+ channel histidine kinase. (715 aa)
	phoR-3	Sensory box histidine kinase PhoR; Signal transduction histidine kinase. (513 aa)
	phyB-2	Phytochrome B; Signal transduction histidine kinase. (697 aa)
	ACPL_3519	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain. (1038 aa)
	phy1-2	Signal transduction histidine kinase. (701 aa)
	ACPL_3560	Serine/threonine protein kinase; Predicted ATPase. (1828 aa)
	ACPL_3699	Sensor protein kinase walK; Signal transduction histidine kinase. (690 aa)
	ACPL_3780	Magnesium or manganese-dependent protein phosphatase; FOG: PAS/PAC domain. (1149 aa)
	phoR-5	Sensory box histidine kinase PhoR; Signal transduction histidine kinase. (531 aa)
	rsbU-5	Uncharacterized protein; Serine phosphatase RsbU, regulator of sigma subunit. (670 aa)
	ACPL_4605	PAS/PAC sensor hybrid histidine kinase; FOG: PAS/PAC domain. (1368 aa)
	phy1-4	Signal transduction histidine kinase. (722 aa)
	phy1-5	Signal transduction histidine kinase. (530 aa)
	ACPL_4649	Response regulator receiver sensor signal transduction histidine kinase; Serine phosphatase RsbU, regulator of sigma subunit. (1346 aa)
	ACPL_4841	Phosphoserine phosphatase rsbP; Serine phosphatase RsbU, regulator of sigma subunit. (685 aa)
	phyB-3	Phytochrome B; Signal transduction histidine kinase. (625 aa)
	ACPL_5044	y4lL-like uncharacterized protein; FOG: GGDEF domain. (671 aa)
	phy1-6	Putative histidine kinase, classic; Osmosensitive K+ channel histidine kinase. (780 aa)
	ACPL_5362	yegE-like uncharacterized protein; FOG: GGDEF domain. (611 aa)
	ACPL_6090	Signaling protein ykoW; Signal transduction histidine kinase. (513 aa)
	ACPL_6637	Signal transduction histidine kinase. (765 aa)
	ACPL_6738	Signal transduction histidine kinase. (673 aa)
	ACPL_6886	Signaling protein ykoW; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain. (906 aa)
	ACPL_7022	y4lL-like uncharacterized protein; FOG: GGDEF domain. (600 aa)
	ACPL_7037	Signaling protein ykoW; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain. (1004 aa)
	ACPL_7381	Putative signaling protein; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain. (874 aa)
	ACPL_7563	Signal transduction histidine kinase. (512 aa)
	ACPL_7891	Sensor kinase protein rcsC; Signal transduction histidine kinase. (451 aa)
	ACPL_8301	Hypothetical protein. (153 aa)

Your Current Organism:

Actinoplanes sp. SE50110

NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACPL_1150	ACPL_1216	ACPL_1150	ACPL_1216	y4lL-like uncharacterized protein; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain.	y4lL-like uncharacterized protein; FOG: GGDEF domain.	0.857
ACPL_1150	ACPL_1400	ACPL_1150	ACPL_1400	y4lL-like uncharacterized protein; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain.	Diguanylate cyclase; FOG: PAS/PAC domain.	0.464
ACPL_1150	ACPL_2016	ACPL_1150	ACPL_2016	y4lL-like uncharacterized protein; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain.	Sensor histidine kinase and response regulator of a two component complex; FOG: PAS/PAC domain.	0.636
ACPL_1150	ACPL_2101	ACPL_1150	ACPL_2101	y4lL-like uncharacterized protein; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain.	PAS/PAC sensor hybrid histidine kinase; Signal transduction histidine kinase.	0.510
ACPL_1150	ACPL_2192	ACPL_1150	ACPL_2192	y4lL-like uncharacterized protein; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain.	Signal transduction histidine kinase.	0.891
ACPL_1150	ACPL_2379	ACPL_1150	ACPL_2379	y4lL-like uncharacterized protein; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain.	PAS/PAC sensor hybrid histidine kinase; Signal transduction histidine kinase.	0.510
ACPL_1150	ACPL_2823	ACPL_1150	ACPL_2823	y4lL-like uncharacterized protein; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain.	Signaling protein ykoW; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain.	0.537
ACPL_1150	ACPL_306	ACPL_1150	ACPL_306	y4lL-like uncharacterized protein; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain.	Signal transduction histidine kinase.	0.620
ACPL_1150	ACPL_3374	ACPL_1150	ACPL_3374	y4lL-like uncharacterized protein; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain.	Signaling protein ykoW; FOG: GGDEF domain.	0.915
ACPL_1150	ACPL_3378	ACPL_1150	ACPL_3378	y4lL-like uncharacterized protein; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain.	PAS/PAC sensor hybrid histidine kinase; Signal transduction histidine kinase.	0.805
ACPL_1150	ACPL_3427	ACPL_1150	ACPL_3427	y4lL-like uncharacterized protein; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain.	Two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR; Osmosensitive K+ channel histidine kinase.	0.983
ACPL_1150	ACPL_3519	ACPL_1150	ACPL_3519	y4lL-like uncharacterized protein; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain.	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain.	0.905
ACPL_1150	ACPL_3560	ACPL_1150	ACPL_3560	y4lL-like uncharacterized protein; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain.	Serine/threonine protein kinase; Predicted ATPase.	0.557
ACPL_1150	ACPL_3780	ACPL_1150	ACPL_3780	y4lL-like uncharacterized protein; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain.	Magnesium or manganese-dependent protein phosphatase; FOG: PAS/PAC domain.	0.834
ACPL_1150	ACPL_4605	ACPL_1150	ACPL_4605	y4lL-like uncharacterized protein; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain.	PAS/PAC sensor hybrid histidine kinase; FOG: PAS/PAC domain.	0.760
ACPL_1150	ACPL_4649	ACPL_1150	ACPL_4649	y4lL-like uncharacterized protein; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain.	Response regulator receiver sensor signal transduction histidine kinase; Serine phosphatase RsbU, regulator of sigma subunit.	0.982
ACPL_1150	ACPL_4841	ACPL_1150	ACPL_4841	y4lL-like uncharacterized protein; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain.	Phosphoserine phosphatase rsbP; Serine phosphatase RsbU, regulator of sigma subunit.	0.523
ACPL_1150	ACPL_5044	ACPL_1150	ACPL_5044	y4lL-like uncharacterized protein; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain.	y4lL-like uncharacterized protein; FOG: GGDEF domain.	0.812
ACPL_1150	ACPL_5362	ACPL_1150	ACPL_5362	y4lL-like uncharacterized protein; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain.	yegE-like uncharacterized protein; FOG: GGDEF domain.	0.830
ACPL_1150	ACPL_5520	ACPL_1150	ACPL_5520	y4lL-like uncharacterized protein; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain.	Putative PAS/PAC sensor protein; FOG: PAS/PAC domain.	0.760