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ACPL_129 ACPL_129 ACPL_1281 ACPL_1281 ACPL_1236 ACPL_1236 ACPL_1208 ACPL_1208 ACPL_1120 ACPL_1120 ACPL_1066 ACPL_1066 ACPL_881 ACPL_881 ACPL_8281 ACPL_8281 ACPL_8280 ACPL_8280 ACPL_8227 ACPL_8227 ACPL_8179 ACPL_8179 ACPL_8003 ACPL_8003 phoP phoP cheB-7 cheB-7 ACPL_7931 ACPL_7931 ACPL_7929 ACPL_7929 ACPL_7888 ACPL_7888 ACPL_7878 ACPL_7878 ACPL_7541 ACPL_7541 ACPL_7236 ACPL_7236 ACPL_7208 ACPL_7208 ACPL_7207 ACPL_7207 cheB-6 cheB-6 ACPL_7130 ACPL_7130 cheY cheY ACPL_7094 ACPL_7094 ACPL_7025 ACPL_7025 ACPL_701 ACPL_701 ACPL_699 ACPL_699 ACPL_694 ACPL_694 ACPL_6885 ACPL_6885 ACPL_6868 ACPL_6868 ACPL_6856 ACPL_6856 ACPL_6805 ACPL_6805 ACPL_6738 ACPL_6738 ACPL_6729 ACPL_6729 ACPL_6691 ACPL_6691 ACPL_6608 ACPL_6608 ACPL_6578 ACPL_6578 ACPL_6554 ACPL_6554 ACPL_6460 ACPL_6460 ACPL_6207 ACPL_6207 ACPL_6136 ACPL_6136 ACPL_6019 ACPL_6019 ACPL_583 ACPL_583 ACPL_580 ACPL_580 ACPL_5700 ACPL_5700 ACPL_5696 ACPL_5696 ACPL_5667 ACPL_5667 ACPL_5392 ACPL_5392 ACPL_5353 ACPL_5353 ACPL_5320 ACPL_5320 ACPL_5273 ACPL_5273 ACPL_5264 ACPL_5264 ACPL_5253 ACPL_5253 mprA mprA ACPL_5146 ACPL_5146 arcB-2 arcB-2 cheB-5 cheB-5 ACPL_5140 ACPL_5140 ACPL_5063 ACPL_5063 ACPL_4809 ACPL_4809 ACPL_4806 ACPL_4806 ACPL_4800 ACPL_4800 resD resD ACPL_4664 ACPL_4664 ACPL_4649 ACPL_4649 ACPL_4564 ACPL_4564 ACPL_4299 ACPL_4299 ACPL_4239 ACPL_4239 ACPL_4192 ACPL_4192 ACPL_4156 ACPL_4156 ACPL_4117 ACPL_4117 ACPL_4048 ACPL_4048 ACPL_399 ACPL_399 ACPL_398 ACPL_398 ACPL_3849 ACPL_3849 ACPL_3818 ACPL_3818 ACPL_379 ACPL_379 ACPL_3741 ACPL_3741 ACPL_3707 ACPL_3707 ACPL_3580 ACPL_3580 ACPL_3568 ACPL_3568 ACPL_3534 ACPL_3534 ACPL_3477 ACPL_3477 phoB-3 phoB-3 etr2-2 etr2-2 ACPL_3425 ACPL_3425 ACPL_3421 ACPL_3421 cckA cckA ACPL_3379 ACPL_3379 ACPL_3378 ACPL_3378 barA barA tcrA-2 tcrA-2 phoB-2 phoB-2 tcrA tcrA ACPL_3223 ACPL_3223 cutR cutR ACPL_3186 ACPL_3186 rcaC rcaC cyaC cyaC ACPL_2932 ACPL_2932 tcsA-3 tcsA-3 ACPL_2513 ACPL_2513 ACPL_2473 ACPL_2473 ACPL_2448 ACPL_2448 phoR phoR phoB phoB ACPL_2379 ACPL_2379 ACPL_2319 ACPL_2319 ACPL_2318 ACPL_2318 ACPL_2274 ACPL_2274 ACPL_2260 ACPL_2260 ACPL_2245 ACPL_2245 ACPL_2205 ACPL_2205 ACPL_2198 ACPL_2198 ACPL_2192 ACPL_2192 tcsA-2 tcsA-2 ACPL_2101 ACPL_2101 ompR ompR ACPL_1954 ACPL_1954 ACPL_1915 ACPL_1915 ACPL_1818 ACPL_1818 degU degU tcsA tcsA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ACPL_129Transcriptional regulatory protein degU; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain. (209 aa)
ACPL_1281Chemotaxis response regulator protein-glutamate methylesterase; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain. (218 aa)
ACPL_1236Chemotaxis response regulator protein-glutamate methylesterase; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (292 aa)
ACPL_1208Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (221 aa)
ACPL_1120Putative transcriptional regulator ycf27; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (128 aa)
ACPL_1066Transcriptional regulatory protein yycF; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (229 aa)
ACPL_881Nitrate/nitrite response regulator protein narP; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (221 aa)
ACPL_8281Putative transcriptional regulator ycf27; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (234 aa)
ACPL_8280Chemotaxis response regulator protein-glutamate methylesterase; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (245 aa)
ACPL_8227Signal transduction histidine kinase. (618 aa)
ACPL_8179Putative transcriptional regulator ycf27; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (232 aa)
ACPL_8003Two component transcriptional regulator, LuxR family; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain. (282 aa)
phoPTranscriptional regulatory protein yycF; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (232 aa)
cheB-7Two-component system, chemotaxis family, response regulator CheB; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. (393 aa)
ACPL_7931Putative transcriptional regulator ycf27; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (131 aa)
ACPL_7929Ycf27-like probable transcriptional regulator; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (120 aa)
ACPL_7888Putative transcriptional regulator ycf27; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (140 aa)
ACPL_7878Sensory transduction protein regX3; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (227 aa)
ACPL_7541Transcriptional regulatory protein yycF; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (242 aa)
ACPL_7236Nitrate/nitrite response regulator protein narP; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (219 aa)
ACPL_7208Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (130 aa)
ACPL_7207Integral membrane sensor hybrid histidine kinase; Signal transduction histidine kinase. (917 aa)
cheB-6Two-component system, chemotaxis family, response regulator CheB; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. (345 aa)
ACPL_7130Putative transcriptional regulator ycf27; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (126 aa)
cheYTranscriptional regulatory protein resD; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (123 aa)
ACPL_7094Two component transcriptional regulator, winged helix family; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (220 aa)
ACPL_7025Two component transcriptional regulator, LuxR family; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain. (212 aa)
ACPL_701Putative transcriptional regulator ycf27; FOG: CheY-like receiver. (151 aa)
ACPL_699Chemotaxis response regulator protein-glutamate methylesterase of group 3 operon; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains. (397 aa)
ACPL_694ykoG-like uncharacterized transcriptional regulatory protein; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (243 aa)
ACPL_6885Nitrate/nitrite response regulator protein narP; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (214 aa)
ACPL_6868Transcriptional regulatory protein degU; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (205 aa)
ACPL_6856Thioredoxin reductase. (552 aa)
ACPL_6805yhcZ-like uncharacterized transcriptional regulatory protein; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain. (208 aa)
ACPL_6738Signal transduction histidine kinase. (673 aa)
ACPL_6729Two component transcriptional regulator, LuxR family; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain. (216 aa)
ACPL_6691Alkaline phosphatase synthesis transcriptional regulatory protein sphR; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (230 aa)
ACPL_6608Sensor protein vraS; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain. (518 aa)
ACPL_6578yhcZ-like uncharacterized transcriptional regulatory protein; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (210 aa)
ACPL_6554Alkaline phosphatase synthesis transcriptional regulatory protein phoP; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (213 aa)
ACPL_6460Chemotaxis response regulator protein-glutamate methylesterase; Response regulator containing a CheY-like receiver domain and a GGDEF domain. (327 aa)
ACPL_6207Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (220 aa)
ACPL_6136Transcriptional regulatory protein yycF; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (228 aa)
ACPL_6019Putative transcriptional regulator ycf27; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (222 aa)
ACPL_583Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (214 aa)
ACPL_580Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (161 aa)
ACPL_5700Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain. (220 aa)
ACPL_5696Putative transcriptional regulator ycf27; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (259 aa)
ACPL_5667yxjL-like uncharacterized transcriptional regulatory protein; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain. (194 aa)
ACPL_5392yxjL-like uncharacterized transcriptional regulatory protein; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (215 aa)
ACPL_5353Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (216 aa)
ACPL_5320Putative transcriptional regulator ycf27; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (129 aa)
ACPL_5273yfiK-like uncharacterized transcriptional regulatory protein; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (213 aa)
ACPL_5264Transcriptional regulatory protein degU; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain. (236 aa)
ACPL_5253yxjL-like uncharacterized transcriptional regulatory protein; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (238 aa)
mprAResponse regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (238 aa)
ACPL_5146Transcriptional regulatory protein desR; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (212 aa)
arcB-2Multi-sensor signal transduction histidine kinase; Response regulator containing a CheY-like receiver domain and a GGDEF domain. (665 aa)
cheB-5Two-component system, chemotaxis family, response regulator CheB; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. (357 aa)
ACPL_5140Two-component system, chemotaxis family, sensor kinase CheA; Chemotaxis protein histidine kinase and related kinases. (702 aa)
ACPL_5063Alkaline phosphatase synthesis transcriptional regulatory protein sphR; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (234 aa)
ACPL_4809Two-component system sensor protein; Signal transduction histidine kinase. (774 aa)
ACPL_4806Putative transcriptional regulator ycf27; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (229 aa)
ACPL_4800Two-component system, cell cycle sensor kinase and response regulator; Signal transduction histidine kinase. (619 aa)
resDTranscriptional regulatory protein yycF; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (232 aa)
ACPL_4664Putative transcriptional regulator ycf27; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (149 aa)
ACPL_4649Response regulator receiver sensor signal transduction histidine kinase; Serine phosphatase RsbU, regulator of sigma subunit. (1346 aa)
ACPL_4564Transcriptional regulatory protein degU; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (214 aa)
ACPL_4299yfiK-like uncharacterized transcriptional regulatory protein; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (203 aa)
ACPL_4239Transcriptional regulatory protein degU; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (227 aa)
ACPL_4192Putative transcriptional regulator ycf27; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (224 aa)
ACPL_4156Transcriptional regulatory protein degU; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (216 aa)
ACPL_4117Transcriptional regulatory protein uhpA; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain. (202 aa)
ACPL_4048Putative transcriptional regulator ycf27; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (131 aa)
ACPL_399Chemotaxis response regulator protein-glutamate methylesterase; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (182 aa)
ACPL_398GAF sensor hybrid histidine kinase; FOG: HAMP domain. (1465 aa)
ACPL_3849Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (216 aa)
ACPL_3818Two-component system, NarL family, response regulator DesR; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (203 aa)
ACPL_379Acetoacetate metabolism regulatory protein atoC; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains. (524 aa)
ACPL_3741Transcriptional regulatory protein yycF; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (253 aa)
ACPL_3707Sensor histidine kinase/response regulator; FOG: HAMP domain. (1498 aa)
ACPL_3580Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain. (215 aa)
ACPL_3568Two component transcriptional regulator, LuxR family; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (214 aa)
ACPL_3534Two-component hybrid sensor and regulator; Signal transduction histidine kinase. (902 aa)
ACPL_3477Putative transcriptional regulator ycf27; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (119 aa)
phoB-3Putative transcriptional regulator ycf27; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (149 aa)
etr2-2Ethylene receptor 2; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (259 aa)
ACPL_3425Phosphate regulon transcriptional regulatory protein phoB; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (155 aa)
ACPL_3421Osmosensitive K+ channel histidine kinase. (629 aa)
cckAOsmosensitive K+ channel histidine kinase. (779 aa)
ACPL_3379Putative transcriptional regulator ycf27; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (126 aa)
ACPL_3378PAS/PAC sensor hybrid histidine kinase; Signal transduction histidine kinase. (654 aa)
barASensory box histidine kinase/response regulator; Signal transduction histidine kinase. (1418 aa)
tcrA-2Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (224 aa)
phoB-2Phosphate regulon transcriptional regulatory protein phoB; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (227 aa)
tcrAResponse regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (227 aa)
ACPL_3223Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (223 aa)
cutRPutative transcriptional regulator ycf27; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (219 aa)
ACPL_3186Transcriptional regulatory protein degU; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (220 aa)
rcaCProtein rcaC; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (225 aa)
cyaCTranscriptional regulatory protein resD; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (119 aa)
ACPL_2932Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (240 aa)
tcsA-3Signal transduction histidine kinase. (606 aa)
ACPL_2513Transcriptional regulatory protein degU; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (220 aa)
ACPL_2473Putative transcriptional regulator ycf27; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (131 aa)
ACPL_2448Transcriptional regulatory protein zraR; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains. (400 aa)
phoRSensory box histidine kinase PhoR; Signal transduction histidine kinase. (653 aa)
phoBPutative transcriptional regulator ycf27; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (151 aa)
ACPL_2379PAS/PAC sensor hybrid histidine kinase; Signal transduction histidine kinase. (787 aa)
ACPL_2319Putative transcriptional regulator ycf27; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (122 aa)
ACPL_2318Signal transduction histidine kinase. (825 aa)
ACPL_2274Two-component system, cell cycle sensor kinase and response regulator; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (525 aa)
ACPL_2260Sensor histidine kinase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. (952 aa)
ACPL_2245Response regulator containing a CheY-like receiver domain and a GGDEF domain. (279 aa)
ACPL_2205Two component transcriptional regulator, winged helix family; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (230 aa)
ACPL_2198Two component transcriptional regulator, LuxR family; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (213 aa)
ACPL_2192Signal transduction histidine kinase. (614 aa)
tcsA-2PAS/PAC sensor hybrid histidine kinase; Signal transduction histidine kinase. (642 aa)
ACPL_2101PAS/PAC sensor hybrid histidine kinase; Signal transduction histidine kinase. (659 aa)
ompRTranscriptional regulatory protein yycF; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (124 aa)
ACPL_1954Transcriptional regulatory protein ydfI; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (223 aa)
ACPL_1915Transcriptional regulatory protein liaR; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (215 aa)
ACPL_1818Response regulator with putative antiterminator output domain. (206 aa)
degUTranscriptional regulatory protein degU; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (222 aa)
tcsAPAS/PAC sensor hybrid histidine kinase; Signal transduction histidine kinase. (500 aa)
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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