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ACPL_1006 ACPL_1006 ACPL_1564 ACPL_1564 glnA glnA gltB gltB gltD gltD purA purA purB purB purQ purQ purF purF gs1 gs1 gabT gabT aspC-2 aspC-2 gabD gabD ykrU ykrU ACPL_4079 ACPL_4079 gabT-2 gabT-2 gadB gadB ACPL_4372 ACPL_4372 asn1 asn1 ald ald putA putA ACPL_6083 ACPL_6083 asnH asnH ald-2 ald-2 argH argH argG argG carB carB carA carA pyrB pyrB purA-2 purA-2 aat3 aat3 asnB asnB ACPL_7231 ACPL_7231 ACPL_7410 ACPL_7410 glmS glmS nadB nadB glmS-2 glmS-2
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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ACPL_1006Asparagine synthase (glutamine-hydrolyzing). (612 aa)
ACPL_1564Glutamine synthetase. (450 aa)
glnAGlutamine synthetase. (474 aa)
gltBGlutamate synthase domain 2. (1517 aa)
gltDNADPH-dependent glutamate synthase beta chain and related oxidoreductases. (489 aa)
purAAdenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (430 aa)
purBAdenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (473 aa)
purQPhosphoribosylformylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...] (233 aa)
purFAmidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (524 aa)
gs1Glutamine synthetase. (335 aa)
gabT4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase; 4-aminobutyrate aminotransferase and related aminotransferases; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (423 aa)
aspC-2Aspartate/tyrosine/aromatic aminotransferase. (391 aa)
gabDSuccinate-semialdehyde dehydrogenase (NADP+); NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family. (409 aa)
ykrUNitrilase-like protein; Predicted amidohydrolase. (267 aa)
ACPL_4079Succinate-semialdehyde dehydrogenase (NADP+); NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family. (459 aa)
gabT-24-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase; 4-aminobutyrate aminotransferase and related aminotransferases; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (446 aa)
gadBGlutamate decarboxylase and related PLP-dependent proteins; Belongs to the group II decarboxylase family. (450 aa)
ACPL_4372Predicted ornithine cyclodeaminase, mu-crystallin homolog. (346 aa)
asn1Asparagine synthase (glutamine-hydrolyzing). (624 aa)
aldAlanine dehydrogenase; Belongs to the AlaDH/PNT family. (372 aa)
putANAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family. (1114 aa)
ACPL_6083Aspartate/tyrosine/aromatic aminotransferase. (417 aa)
asnHAsparagine synthase (glutamine-hydrolyzing). (733 aa)
ald-2Alanine dehydrogenase. (379 aa)
argHArgininosuccinate lyase. (476 aa)
argGArgininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (411 aa)
carBCarbamoylphosphate synthase large subunit (split gene in MJ); Belongs to the CarB family. (1105 aa)
carACarbamoylphosphate synthase small subunit; Belongs to the CarA family. (368 aa)
pyrBAspartate carbamoyltransferase catalytic subunit; Ornithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (306 aa)
purA-2Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (408 aa)
aat3Aminotransferase; Aspartate/tyrosine/aromatic aminotransferase. (400 aa)
asnBAsparagine synthase (glutamine-hydrolyzing). (590 aa)
ACPL_7231Glutamine synthetase. (448 aa)
ACPL_7410NAD-specific glutamate dehydrogenase. (1652 aa)
glmSGlucosamine-fructose-6-phosphate aminotransferase (isomerizing); Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains. (345 aa)
nadBL-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. (548 aa)
glmS-2Glucosamine-fructose-6-phosphate aminotransferase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (639 aa)
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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