(27 nodes) Butanoate metabolism network (Actinoplanes sp. SE50110)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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proteins of unknown 3D structure

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Predicted Interactions

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Your Input:
	mvaB	hydroxymethylglutaryl-CoA lyase; Isopropylmalate/homocitrate/citramalate synthases. (292 aa)
	sdhB	Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit. (247 aa)
	sdhA	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit. (648 aa)
	sdhC	Succinate dehydrogenase cytochrome b-556 subunit. (246 aa)
	gabT	4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase; 4-aminobutyrate aminotransferase and related aminotransferases; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (423 aa)
	fadB	3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase; 3-hydroxyacyl-CoA dehydrogenase. (676 aa)
	fadA	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (410 aa)
	ACPL_2746	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). (255 aa)
	gabD	Succinate-semialdehyde dehydrogenase (NADP+); NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family. (409 aa)
	pcaI	Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit. (255 aa)
	pcaJ	Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit. (210 aa)
	ACPL_4079	Succinate-semialdehyde dehydrogenase (NADP+); NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family. (459 aa)
	gabT-2	4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase; 4-aminobutyrate aminotransferase and related aminotransferases; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (446 aa)
	gadB	Glutamate decarboxylase and related PLP-dependent proteins; Belongs to the group II decarboxylase family. (450 aa)
	ACPL_4503	Enoyl-CoA hydratase/carnithine racemase. (336 aa)
	ACPL_5497	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (425 aa)
	ACPL_5738	Acetyl-CoA acetyltransferase; Belongs to the enoyl-CoA hydratase/isomerase family. (879 aa)
	ilvH	Acetolactate synthase, small (regulatory) subunit. (172 aa)
	ilvB	Acetolactate synthase 1 catalytic subunit; Thiamine pyrophosphate-requiring enzymes. (609 aa)
	ilvG	Acetolactate synthase I/II/III large subunit; Thiamine pyrophosphate-requiring enzymes; Belongs to the TPP enzyme family. (536 aa)
	ACPL_7418	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa)
	ACPL_7436	3-hydroxyacyl-CoA dehydrogenase. (282 aa)
	sdhA-2	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit. (629 aa)
	sdhb	Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit. (330 aa)
	porA	Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit. (617 aa)
	ACPL_7853	Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit. (334 aa)
	ACPL_948	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (414 aa)

Your Current Organism:

Actinoplanes sp. SE50110

NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACPL_2746	mvaB	ACPL_2746	ACPL_145	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).	hydroxymethylglutaryl-CoA lyase; Isopropylmalate/homocitrate/citramalate synthases.	0.900
ACPL_2746	pcaI	ACPL_2746	ACPL_3243	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).	Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit.	0.915
ACPL_2746	pcaJ	ACPL_2746	ACPL_3244	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).	Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit.	0.918
ACPL_4079	ACPL_7853	ACPL_4079	ACPL_7853	Succinate-semialdehyde dehydrogenase (NADP+); NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family.	Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit.	0.811
ACPL_4079	gabD	ACPL_4079	ACPL_3084	Succinate-semialdehyde dehydrogenase (NADP+); NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family.	Succinate-semialdehyde dehydrogenase (NADP+); NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family.	0.902
ACPL_4079	gabT	ACPL_4079	ACPL_2477	Succinate-semialdehyde dehydrogenase (NADP+); NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family.	4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase; 4-aminobutyrate aminotransferase and related aminotransferases; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.931
ACPL_4079	gabT-2	ACPL_4079	ACPL_4080	Succinate-semialdehyde dehydrogenase (NADP+); NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family.	4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase; 4-aminobutyrate aminotransferase and related aminotransferases; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.984
ACPL_4079	porA	ACPL_4079	ACPL_7852	Succinate-semialdehyde dehydrogenase (NADP+); NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family.	Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit.	0.854
ACPL_4079	sdhA	ACPL_4079	ACPL_1722	Succinate-semialdehyde dehydrogenase (NADP+); NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family.	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit.	0.926
ACPL_4079	sdhA-2	ACPL_4079	ACPL_7654	Succinate-semialdehyde dehydrogenase (NADP+); NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family.	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit.	0.926
ACPL_4079	sdhB	ACPL_4079	ACPL_1721	Succinate-semialdehyde dehydrogenase (NADP+); NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family.	Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit.	0.913
ACPL_4079	sdhC	ACPL_4079	ACPL_1723	Succinate-semialdehyde dehydrogenase (NADP+); NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family.	Succinate dehydrogenase cytochrome b-556 subunit.	0.900
ACPL_4079	sdhb	ACPL_4079	ACPL_7655	Succinate-semialdehyde dehydrogenase (NADP+); NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family.	Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit.	0.913
ACPL_4503	ACPL_5497	ACPL_4503	ACPL_5497	Enoyl-CoA hydratase/carnithine racemase.	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.651
ACPL_4503	ACPL_7418	ACPL_4503	ACPL_7418	Enoyl-CoA hydratase/carnithine racemase.	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.651
ACPL_4503	ACPL_7436	ACPL_4503	ACPL_7436	Enoyl-CoA hydratase/carnithine racemase.	3-hydroxyacyl-CoA dehydrogenase.	0.949
ACPL_4503	ACPL_948	ACPL_4503	ACPL_948	Enoyl-CoA hydratase/carnithine racemase.	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.651
ACPL_4503	fadA	ACPL_4503	ACPL_2501	Enoyl-CoA hydratase/carnithine racemase.	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.651
ACPL_4503	fadB	ACPL_4503	ACPL_2500	Enoyl-CoA hydratase/carnithine racemase.	3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase; 3-hydroxyacyl-CoA dehydrogenase.	0.942
ACPL_5497	ACPL_4503	ACPL_5497	ACPL_4503	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	Enoyl-CoA hydratase/carnithine racemase.	0.651