STRINGSTRING
CMV25_06010 CMV25_06010 CMV25_06685 CMV25_06685 CMV25_06815 CMV25_06815 pta pta tkt tkt CMV25_09470 CMV25_09470 CMV25_09475 CMV25_09475 CMV25_09480 CMV25_09480 CMV25_01665 CMV25_01665 CMV25_01660 CMV25_01660 fabH fabH acpP acpP fabK fabK fabD fabD fabG fabG fabF fabF accB accB fabZ fabZ accC accC accD accD CMV25_01605 CMV25_01605 GCA_001591765_00465 GCA_001591765_00465 spxB spxB CMV25_01100 CMV25_01100 CMV25_01095 CMV25_01095 nifJ nifJ CMV25_02440 CMV25_02440 CMV25_02445 CMV25_02445 CMV25_02450 CMV25_02450 leuD leuD leuC leuC leuB leuB leuA leuA CMV25_03635 CMV25_03635 CMV25_03640 CMV25_03640 glnA glnA CMV25_03650 CMV25_03650 GCA_001591765_00598 GCA_001591765_00598 GCA_001591765_00599 GCA_001591765_00599 GCA_001591765_00600 GCA_001591765_00600 GCA_001591765_00601 GCA_001591765_00601 CMV25_03775 CMV25_03775 CMV25_03830 CMV25_03830 rpiA rpiA gap gap CMV25_10175 CMV25_10175 CMV25_10240 CMV25_10240 CMV25_10335 CMV25_10335 GCA_001591765_00776 GCA_001591765_00776 GCA_001591765_00777 GCA_001591765_00777 ilvD ilvD ilvB ilvB ilvN ilvN ilvC ilvC ilvA ilvA CMV25_10810 CMV25_10810 acnA acnA CMV25_10820 CMV25_10820 ldh ldh GCA_001591765_00902 GCA_001591765_00902 GCA_001591765_00903 GCA_001591765_00903 CMV25_00595 CMV25_00595 CMV25_05030 CMV25_05030 GCA_001591765_01103 GCA_001591765_01103 gpmA gpmA CMV25_07125 CMV25_07125 tpiA tpiA ackA ackA CMV25_07950 CMV25_07950 zwf zwf prs prs eno eno pflB pflB CMV25_02670 CMV25_02670 fba fba dltD dltD dltC dltC dltB dltB dltA dltA CMV25_10555 CMV25_10555 pfkA pfkA pyk pyk nifJ-2 nifJ-2 prs-2 prs-2 alsS alsS budA budA CMV25_09915 CMV25_09915 manA manA CMV25_08305 CMV25_08305 fbp fbp CMV25_10620 CMV25_10620 CMV25_10615 CMV25_10615 CMV25_10605 CMV25_10605 CMV25_02555 CMV25_02555 GCA_001591765_01867 GCA_001591765_01867 CMV25_04915 CMV25_04915 acpP-2 acpP-2 CMV25_01030 CMV25_01030 CMV25_01035 CMV25_01035 kbaY kbaY pgi pgi lpdA lpdA CMV25_01680 CMV25_01680 CMV25_01685 CMV25_01685 CMV25_01690 CMV25_01690 CMV25_01695 CMV25_01695 CMV25_02100 CMV25_02100 pgk pgk CMV25_04600 CMV25_04600 GCA_001591765_02110 GCA_001591765_02110
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CMV25_06010Unannotated protein; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. (866 aa)
CMV25_06685Unannotated protein. (476 aa)
CMV25_06815Unannotated protein; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (473 aa)
ptaUnannotated protein. (327 aa)
tktUnannotated protein; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (663 aa)
CMV25_09470Unannotated protein. (317 aa)
CMV25_09475Unannotated protein. (333 aa)
CMV25_09480Unannotated protein. (125 aa)
CMV25_01665Unannotated protein. (365 aa)
CMV25_01660Unannotated protein. (145 aa)
fabHUnannotated protein; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (326 aa)
acpPUnannotated protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. (75 aa)
fabKUnannotated protein. (318 aa)
fabDUnannotated protein. (308 aa)
fabGUnannotated protein; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (244 aa)
fabFUnannotated protein; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (415 aa)
accBUnannotated protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (156 aa)
fabZUnannotated protein; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (140 aa)
accCUnannotated protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (456 aa)
accDUnannotated protein; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (293 aa)
CMV25_01605Unannotated protein; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (252 aa)
GCA_001591765_00465Unannotated protein. (220 aa)
spxBUnannotated protein; Belongs to the TPP enzyme family. (374 aa)
CMV25_01100Unannotated protein; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation. (127 aa)
CMV25_01095Unannotated protein. (250 aa)
nifJUnannotated protein. (1180 aa)
CMV25_02440Unannotated protein. (580 aa)
CMV25_02445Unannotated protein. (624 aa)
CMV25_02450Unannotated protein. (174 aa)
leuDUnannotated protein; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (196 aa)
leuCUnannotated protein; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (457 aa)
leuBUnannotated protein; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (345 aa)
leuAUnannotated protein; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (521 aa)
CMV25_03635Unannotated protein. (126 aa)
CMV25_03640Unannotated protein; Belongs to the glutamine synthetase family. (702 aa)
glnAUnannotated protein; Belongs to the glutamine synthetase family. (446 aa)
CMV25_03650Unannotated protein. (120 aa)
GCA_001591765_00598Unannotated protein. (125 aa)
GCA_001591765_00599Unannotated protein. (159 aa)
GCA_001591765_00600Unannotated protein. (230 aa)
GCA_001591765_00601Unannotated protein. (112 aa)
CMV25_03775Unannotated protein. (187 aa)
CMV25_03830Unannotated protein. (243 aa)
rpiAUnannotated protein; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (225 aa)
gapUnannotated protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (337 aa)
CMV25_10175Unannotated protein. (343 aa)
CMV25_10240Unannotated protein. (291 aa)
CMV25_10335Unannotated protein. (705 aa)
GCA_001591765_00776Unannotated protein. (482 aa)
GCA_001591765_00777Unannotated protein. (180 aa)
ilvDUnannotated protein; Belongs to the IlvD/Edd family. (570 aa)
ilvBUnannotated protein. (567 aa)
ilvNUnannotated protein. (158 aa)
ilvCUnannotated protein; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (340 aa)
ilvAUnannotated protein; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (416 aa)
CMV25_10810Unannotated protein. (410 aa)
acnAUnannotated protein; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (869 aa)
CMV25_10820Unannotated protein; Belongs to the citrate synthase family. (441 aa)
ldhUnannotated protein; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (325 aa)
GCA_001591765_00902Unannotated protein. (137 aa)
GCA_001591765_00903Unannotated protein. (142 aa)
CMV25_00595Unannotated protein; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (449 aa)
CMV25_05030Unannotated protein. (249 aa)
GCA_001591765_01103Unannotated protein. (550 aa)
gpmAUnannotated protein; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (231 aa)
CMV25_07125Unannotated protein. (276 aa)
tpiAUnannotated protein; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (252 aa)
ackAUnannotated protein; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (397 aa)
CMV25_07950Unannotated protein; Belongs to the ribulose-phosphate 3-epimerase family. (215 aa)
zwfUnannotated protein; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (494 aa)
prsUnannotated protein; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (321 aa)
enoUnannotated protein; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (441 aa)
pflBUnannotated protein. (766 aa)
CMV25_02670Unannotated protein; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1137 aa)
fbaUnannotated protein. (293 aa)
dltDUnannotated protein. (413 aa)
dltCUnannotated protein; Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC- carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. (79 aa)
dltBUnannotated protein; Could be involved in the transport of activated D-alanine through the membrane. (417 aa)
dltAUnannotated protein; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Belongs to the ATP-dependent AMP-binding [...] (513 aa)
CMV25_10555Unannotated protein. (52 aa)
pfkAUnannotated protein; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (335 aa)
pykUnannotated protein; Belongs to the pyruvate kinase family. (500 aa)
nifJ-2Unannotated protein. (1222 aa)
prs-2Unannotated protein; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (327 aa)
alsSUnannotated protein; Belongs to the TPP enzyme family. (552 aa)
budAUnannotated protein; Belongs to the alpha-acetolactate decarboxylase family. (236 aa)
CMV25_09915Unannotated protein. (337 aa)
manAUnannotated protein; Belongs to the mannose-6-phosphate isomerase type 1 family. (314 aa)
CMV25_08305Unannotated protein. (288 aa)
fbpUnannotated protein. (640 aa)
CMV25_10620Unannotated protein. (289 aa)
CMV25_10615Unannotated protein. (322 aa)
CMV25_10605Unannotated protein. (289 aa)
CMV25_02555Unannotated protein; Belongs to the aldehyde dehydrogenase family. (478 aa)
GCA_001591765_01867Unannotated protein. (598 aa)
CMV25_04915Unannotated protein. (270 aa)
acpP-2Unannotated protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (82 aa)
CMV25_01030Unannotated protein. (479 aa)
CMV25_01035Unannotated protein. (1500 aa)
kbaYUnannotated protein. (281 aa)
pgiUnannotated protein; Belongs to the GPI family. (448 aa)
lpdAUnannotated protein. (470 aa)
CMV25_01680Unannotated protein. (440 aa)
CMV25_01685Unannotated protein. (326 aa)
CMV25_01690Unannotated protein. (370 aa)
CMV25_01695Unannotated protein. (327 aa)
CMV25_02100Unannotated protein. (144 aa)
pgkUnannotated protein; Belongs to the phosphoglycerate kinase family. (398 aa)
CMV25_04600Unannotated protein. (284 aa)
GCA_001591765_02110Unannotated protein. (140 aa)
Your Current Organism:
Lactococcus raffinolactis NBRC100932
NCBI taxonomy Id: 1348633
Other names: L. raffinolactis NBRC 100932, Lactococcus raffinolactis NBRC 100932
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