node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CMV25_01575 | glyA | GCA_001591765_00381 | GCA_001591765_01553 | Unannotated protein; Belongs to the UPF0237 family. | Unannotated protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.555 |
CMV25_01575 | serB | GCA_001591765_00381 | GCA_001591765_01786 | Unannotated protein; Belongs to the UPF0237 family. | Unannotated protein. | 0.504 |
CMV25_01575 | serC | GCA_001591765_00381 | GCA_001591765_01509 | Unannotated protein; Belongs to the UPF0237 family. | Unannotated protein; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. | 0.563 |
CMV25_08645 | eno | GCA_001591765_01508 | GCA_001591765_01372 | Unannotated protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Unannotated protein; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.441 |
CMV25_08645 | glyA | GCA_001591765_01508 | GCA_001591765_01553 | Unannotated protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Unannotated protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.516 |
CMV25_08645 | gpmA | GCA_001591765_01508 | GCA_001591765_01125 | Unannotated protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Unannotated protein; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. | 0.894 |
CMV25_08645 | pta | GCA_001591765_01508 | GCA_001591765_00302 | Unannotated protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Unannotated protein. | 0.470 |
CMV25_08645 | serB | GCA_001591765_01508 | GCA_001591765_01786 | Unannotated protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Unannotated protein. | 0.660 |
CMV25_08645 | serC | GCA_001591765_01508 | GCA_001591765_01509 | Unannotated protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Unannotated protein; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. | 0.998 |
ackA | eno | GCA_001591765_01193 | GCA_001591765_01372 | Unannotated protein; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | Unannotated protein; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.445 |
ackA | pta | GCA_001591765_01193 | GCA_001591765_00302 | Unannotated protein; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | Unannotated protein. | 0.999 |
eno | CMV25_08645 | GCA_001591765_01372 | GCA_001591765_01508 | Unannotated protein; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Unannotated protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.441 |
eno | ackA | GCA_001591765_01372 | GCA_001591765_01193 | Unannotated protein; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Unannotated protein; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | 0.445 |
eno | fba | GCA_001591765_01372 | GCA_001591765_01382 | Unannotated protein; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Unannotated protein. | 0.967 |
eno | glyA | GCA_001591765_01372 | GCA_001591765_01553 | Unannotated protein; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Unannotated protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.432 |
eno | gpmA | GCA_001591765_01372 | GCA_001591765_01125 | Unannotated protein; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Unannotated protein; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. | 0.983 |
eno | kbaY | GCA_001591765_01372 | GCA_001591765_01974 | Unannotated protein; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Unannotated protein. | 0.937 |
eno | pfkA | GCA_001591765_01372 | GCA_001591765_01436 | Unannotated protein; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Unannotated protein; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. | 0.828 |
fba | eno | GCA_001591765_01382 | GCA_001591765_01372 | Unannotated protein. | Unannotated protein; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.967 |
fba | fbp | GCA_001591765_01382 | GCA_001591765_01674 | Unannotated protein. | Unannotated protein. | 0.888 |