STRINGSTRING
pycA pycA fabV fabV dmpC dmpC serBA serBA dapB dapB rpe rpe icd icd MARIT_2159 MARIT_2159 accD accD fbaA fbaA acnB acnB argD2 argD2 folD folD sucC sucC serA2 serA2 serC serC argD1 argD1 norBC norBC MARIT_1618 MARIT_1618 prsA prsA pck pck thrC thrC thrB thrB thrA thrA acs acs MARIT_3145 MARIT_3145 accA accA lpd lpd lysC lysC rpiB rpiB gltX gltX asdA asdA mutA mutA mutB mutB mdh mdh MARIT_0877 MARIT_0877 pfkA pfkA gapA gapA mgsA mgsA MARIT_1250 MARIT_1250 pdhB pdhB nemA nemA hemL hemL hemB hemB hemC hemC hemA hemA xdhA xdhA MARIT_1116 MARIT_1116 aldH aldH MARIT_0504 MARIT_0504 metF metF cysE cysE sirC sirC cobA cobA MARIT_2609 MARIT_2609 cysN cysN cysD cysD cysH cysH metXL metXL fhs fhs pdhC pdhC pdhA pdhA lpdA lpdA MARIT_1308 MARIT_1308 MARIT_0731 MARIT_0731 MARIT_3063 MARIT_3063 sucA sucA sucB sucB serA3 serA3 pgk pgk fbp fbp MARIT_3108 MARIT_3108 aceA aceA aceB aceB phbA phbA MARIT_2198 MARIT_2198 glyA glyA MARIT_1575 MARIT_1575 tkt tkt MARIT_1558 MARIT_1558 dapD dapD tkt-2 tkt-2 lysA lysA sucD sucD pgcA pgcA MARIT_0941 MARIT_0941 MARIT_0940 MARIT_0940 eno eno gltA gltA pdxH pdxH tal tal napB napB napA napA nrfA nrfA MARIT_1710 MARIT_1710 hbd hbd glnA glnA glnII glnII tpiA tpiA gltB gltB gltD gltD MARIT_2551 MARIT_2551 gdhA gdhA paaE paaE pgi pgi MARIT_0186 MARIT_0186 tbsB tbsB tbsA tbsA maeB maeB sdhB sdhB sdhA sdhA sdhC sdhC hemD hemD accC accC accB accB pykA pykA yqjC yqjC gpmI gpmI MARIT_0411 MARIT_0411 MARIT_0437 MARIT_0437 dhaA dhaA yjgB yjgB MARIT_1843 MARIT_1843 ltaA ltaA dapA2 dapA2 gapA2 gapA2 dapF dapF fumC fumC aldB aldB MARIT_1960 MARIT_1960
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
pycAUnannotated protein; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1150 aa)
fabVUnannotated protein; Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon- carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP); Belongs to the TER reductase family. (395 aa)
dmpCUnannotated protein; Belongs to the aldehyde dehydrogenase family. (481 aa)
serBAUnannotated protein; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (630 aa)
dapBUnannotated protein; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (233 aa)
rpeUnannotated protein; Belongs to the ribulose-phosphate 3-epimerase family. (218 aa)
icdUnannotated protein; Belongs to the monomeric-type IDH family. (741 aa)
MARIT_2159Unannotated protein; Belongs to the enoyl-CoA hydratase/isomerase family. (275 aa)
accDUnannotated protein; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA. (285 aa)
fbaAUnannotated protein; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (355 aa)
acnBUnannotated protein. (925 aa)
argD2Unannotated protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (393 aa)
folDUnannotated protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (291 aa)
sucCUnannotated protein; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (398 aa)
serA2Unannotated protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (316 aa)
serCUnannotated protein; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (354 aa)
argD1Unannotated protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (374 aa)
norBCUnannotated protein. (741 aa)
MARIT_1618Unannotated protein. (203 aa)
prsAUnannotated protein. (313 aa)
pckUnannotated protein; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (536 aa)
thrCUnannotated protein. (434 aa)
thrBUnannotated protein; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (307 aa)
thrAUnannotated protein. (813 aa)
acsUnannotated protein; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. (635 aa)
MARIT_3145Unannotated protein. (392 aa)
accAUnannotated protein; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (317 aa)
lpdUnannotated protein. (466 aa)
lysCUnannotated protein; Belongs to the aspartokinase family. (443 aa)
rpiBUnannotated protein. (144 aa)
gltXUnannotated protein; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (509 aa)
asdAUnannotated protein; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (335 aa)
mutAUnannotated protein. (448 aa)
mutBUnannotated protein. (687 aa)
mdhUnannotated protein; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (310 aa)
MARIT_0877Unannotated protein; Belongs to the ribose-phosphate pyrophosphokinase family. (280 aa)
pfkAUnannotated protein; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (327 aa)
gapAUnannotated protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (330 aa)
mgsAUnannotated protein; Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate. (121 aa)
MARIT_1250Unannotated protein. (259 aa)
pdhBUnannotated protein; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (325 aa)
nemAUnannotated protein. (367 aa)
hemLUnannotated protein. (430 aa)
hemBUnannotated protein; Belongs to the ALAD family. (321 aa)
hemCUnannotated protein; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (528 aa)
hemAUnannotated protein; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (422 aa)
xdhAUnannotated protein. (754 aa)
MARIT_1116Unannotated protein. (472 aa)
aldHUnannotated protein; Belongs to the aldehyde dehydrogenase family. (458 aa)
MARIT_0504Unannotated protein; Belongs to the thiolase-like superfamily. Thiolase family. (417 aa)
metFUnannotated protein; Belongs to the methylenetetrahydrofolate reductase family. (317 aa)
cysEUnannotated protein. (256 aa)
sirCUnannotated protein. (193 aa)
cobAUnannotated protein. (255 aa)
MARIT_2609Unannotated protein; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (700 aa)
cysNUnannotated protein; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (453 aa)
cysDUnannotated protein. (302 aa)
cysHUnannotated protein. (205 aa)
metXLUnannotated protein. (1131 aa)
fhsUnannotated protein; Belongs to the formate--tetrahydrofolate ligase family. (561 aa)
pdhCUnannotated protein. (546 aa)
pdhAUnannotated protein; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (329 aa)
lpdAUnannotated protein. (462 aa)
MARIT_1308Unannotated protein. (724 aa)
MARIT_0731Unannotated protein. (233 aa)
MARIT_3063Unannotated protein; Belongs to the aldehyde dehydrogenase family. (513 aa)
sucAUnannotated protein. (924 aa)
sucBUnannotated protein; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (402 aa)
serA3Unannotated protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (314 aa)
pgkUnannotated protein; Belongs to the phosphoglycerate kinase family. (395 aa)
fbpUnannotated protein; Belongs to the FBPase class 1 family. (335 aa)
MARIT_3108Unannotated protein; Belongs to the aspartokinase family. (414 aa)
aceAUnannotated protein. (538 aa)
aceBUnannotated protein; Belongs to the malate synthase family. (531 aa)
phbAUnannotated protein; Belongs to the thiolase-like superfamily. Thiolase family. (394 aa)
MARIT_2198Unannotated protein. (342 aa)
glyAUnannotated protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (424 aa)
MARIT_1575Unannotated protein. (426 aa)
tktUnannotated protein. (316 aa)
MARIT_1558Unannotated protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (435 aa)
dapDUnannotated protein; Belongs to the transferase hexapeptide repeat family. (271 aa)
tkt-2Unannotated protein. (281 aa)
lysAUnannotated protein; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (401 aa)
sucDUnannotated protein; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (293 aa)
pgcAUnannotated protein. (569 aa)
MARIT_0941Unannotated protein. (801 aa)
MARIT_0940Unannotated protein; Belongs to the thiolase-like superfamily. Thiolase family. (396 aa)
enoUnannotated protein; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (429 aa)
gltAUnannotated protein; Belongs to the citrate synthase family. (428 aa)
pdxHUnannotated protein; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). (215 aa)
talUnannotated protein; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (217 aa)
napBUnannotated protein. (231 aa)
napAUnannotated protein; Catalytic subunit of the nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite. (775 aa)
nrfAUnannotated protein; Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process; Belongs to the cytochrome c-552 family. (497 aa)
MARIT_1710Unannotated protein. (211 aa)
hbdUnannotated protein. (295 aa)
glnAUnannotated protein; Belongs to the glutamine synthetase family. (727 aa)
glnIIUnannotated protein. (336 aa)
tpiAUnannotated protein; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (252 aa)
gltBUnannotated protein. (1501 aa)
gltDUnannotated protein. (485 aa)
MARIT_2551Unannotated protein. (388 aa)
gdhAUnannotated protein; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (447 aa)
paaEUnannotated protein. (350 aa)
pgiUnannotated protein; Belongs to the GPI family. (523 aa)
MARIT_0186Unannotated protein. (385 aa)
tbsBUnannotated protein. (442 aa)
tbsAUnannotated protein. (502 aa)
maeBUnannotated protein. (766 aa)
sdhBUnannotated protein. (248 aa)
sdhAUnannotated protein. (671 aa)
sdhCUnannotated protein. (224 aa)
hemDUnannotated protein. (248 aa)
accCUnannotated protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (445 aa)
accBUnannotated protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (161 aa)
pykAUnannotated protein; Belongs to the pyruvate kinase family. (475 aa)
yqjCUnannotated protein. (133 aa)
gpmIUnannotated protein; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (498 aa)
MARIT_0411Unannotated protein; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (881 aa)
MARIT_0437Unannotated protein. (298 aa)
dhaAUnannotated protein. (319 aa)
yjgBUnannotated protein. (334 aa)
MARIT_1843Unannotated protein. (281 aa)
ltaAUnannotated protein. (340 aa)
dapA2Unannotated protein; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (291 aa)
gapA2Unannotated protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (480 aa)
dapFUnannotated protein; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (258 aa)
fumCUnannotated protein; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (465 aa)
aldBUnannotated protein; Belongs to the aldehyde dehydrogenase family. (500 aa)
MARIT_1960Unannotated protein. (434 aa)
Your Current Organism:
Tenacibaculum maritimum
NCBI taxonomy Id: 1349785
Other names: T. maritimum NCIMB 2154, Tenacibaculum maritimum ATCC 43398, Tenacibaculum maritimum NBRC 110778, Tenacibaculum maritimum NCIMB 2154
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