(5 nodes) PKA activation, and AGC-kinase, C-terminal network (Calocera cornea)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A165CTG7	cAMP-dependent protein kinase regulatory subunit. (362 aa)
	A0A165CVY3	Non-specific serine/threonine protein kinase. (572 aa)
	A0A165J0X2	Kinase-like protein. (698 aa)
	A0A165K5S3	Kinase-like protein. (365 aa)
	A0A165KC61	Uncharacterized protein. (1960 aa)

Your Current Organism:

Calocera cornea

NCBI taxonomy Id: 1353952
Other names: C. cornea HHB12733, Calocera cornea HHB12733

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A165CTG7	A0A165CVY3	cAMP-dependent protein kinase regulatory subunit.	Non-specific serine/threonine protein kinase.	0.826
A0A165CTG7	A0A165J0X2	cAMP-dependent protein kinase regulatory subunit.	Kinase-like protein.	0.938
A0A165CTG7	A0A165K5S3	cAMP-dependent protein kinase regulatory subunit.	Kinase-like protein.	0.873
A0A165CVY3	A0A165CTG7	Non-specific serine/threonine protein kinase.	cAMP-dependent protein kinase regulatory subunit.	0.826
A0A165CVY3	A0A165J0X2	Non-specific serine/threonine protein kinase.	Kinase-like protein.	0.689
A0A165CVY3	A0A165KC61	Non-specific serine/threonine protein kinase.	Uncharacterized protein.	0.791
A0A165J0X2	A0A165CTG7	Kinase-like protein.	cAMP-dependent protein kinase regulatory subunit.	0.938
A0A165J0X2	A0A165CVY3	Kinase-like protein.	Non-specific serine/threonine protein kinase.	0.689
A0A165J0X2	A0A165K5S3	Kinase-like protein.	Kinase-like protein.	0.753
A0A165J0X2	A0A165KC61	Kinase-like protein.	Uncharacterized protein.	0.837
A0A165K5S3	A0A165CTG7	Kinase-like protein.	cAMP-dependent protein kinase regulatory subunit.	0.873
A0A165K5S3	A0A165J0X2	Kinase-like protein.	Kinase-like protein.	0.753
A0A165K5S3	A0A165KC61	Kinase-like protein.	Uncharacterized protein.	0.719
A0A165KC61	A0A165CVY3	Uncharacterized protein.	Non-specific serine/threonine protein kinase.	0.791
A0A165KC61	A0A165J0X2	Uncharacterized protein.	Kinase-like protein.	0.837
A0A165KC61	A0A165K5S3	Uncharacterized protein.	Kinase-like protein.	0.719