(29 nodes) RNA Polymerase II Transcription Elongation, and FACT complex network (Calocera cornea)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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Others

textmining

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protein homology

Your Input:
	A0A165CAI6	Uncharacterized protein. (262 aa)
	A0A165D214	Plus-3-domain-containing protein. (525 aa)
	A0A165DCK3	FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...] (598 aa)
	A0A165DIF8	RBP11-like subunits of RNA polymerase. (410 aa)
	A0A165DR93	TPR-like protein. (1102 aa)
	A0A165DRG6	Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene. (119 aa)
	A0A165DUK2	SPT16-domain-containing protein. (1061 aa)
	A0A165E2N7	Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family. (1673 aa)
	A0A165E3P7	Transcription elongation factor. (316 aa)
	A0A165E8V9	CDC73-domain-containing protein. (437 aa)
	A0A165EE96	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (591 aa)
	A0A165EP19	Uncharacterized protein. (538 aa)
	A0A165EXU1	Uncharacterized protein. (199 aa)
	A0A165F0L6	HMG-box. (130 aa)
	A0A165F6X4	Uncharacterized protein. (316 aa)
	A0A165FHA1	TFIIS N-terminal domain-containing protein. (392 aa)
	A0A165FI58	Uncharacterized protein. (170 aa)
	A0A165G6W6	Uncharacterized protein. (466 aa)
	A0A165GAE8	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1263 aa)
	A0A165H923	Transcription elongation factor 1 homolog; Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions. Belongs to the ELOF1 family. (122 aa)
	A0A165HHA6	Transcription elongation factor SPT5; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene. (1166 aa)
	A0A165HKN3	RNA polymerase II. (135 aa)
	A0A165HW95	Uncharacterized protein. (442 aa)
	A0A165HY08	Uncharacterized protein. (311 aa)
	A0A165IJ20	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (119 aa)
	A0A165ISB0	DNA-directed RNA polymerase II. (126 aa)
	A0A165JFJ3	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1786 aa)
	A0A165JR24	Uncharacterized protein. (395 aa)
	A0A165JX70	Uncharacterized protein. (75 aa)

Your Current Organism:

Calocera cornea

NCBI taxonomy Id: 1353952
Other names: C. cornea HHB12733, Calocera cornea HHB12733

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A165CAI6	A0A165D214	Uncharacterized protein.	Plus-3-domain-containing protein.	0.485
A0A165CAI6	A0A165DCK3	Uncharacterized protein.	FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...]	0.629
A0A165CAI6	A0A165DIF8	Uncharacterized protein.	RBP11-like subunits of RNA polymerase.	0.771
A0A165CAI6	A0A165DR93	Uncharacterized protein.	TPR-like protein.	0.463
A0A165CAI6	A0A165DRG6	Uncharacterized protein.	Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.	0.767
A0A165CAI6	A0A165DUK2	Uncharacterized protein.	SPT16-domain-containing protein.	0.740
A0A165CAI6	A0A165E2N7	Uncharacterized protein.	Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family.	0.534
A0A165CAI6	A0A165E3P7	Uncharacterized protein.	Transcription elongation factor.	0.696
A0A165CAI6	A0A165E8V9	Uncharacterized protein.	CDC73-domain-containing protein.	0.512
A0A165CAI6	A0A165EE96	Uncharacterized protein.	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II.	0.764
A0A165CAI6	A0A165EP19	Uncharacterized protein.	Uncharacterized protein.	0.741
A0A165CAI6	A0A165EXU1	Uncharacterized protein.	Uncharacterized protein.	0.463
A0A165CAI6	A0A165F0L6	Uncharacterized protein.	HMG-box.	0.629
A0A165CAI6	A0A165F6X4	Uncharacterized protein.	Uncharacterized protein.	0.463
A0A165CAI6	A0A165FHA1	Uncharacterized protein.	TFIIS N-terminal domain-containing protein.	0.404
A0A165CAI6	A0A165FI58	Uncharacterized protein.	Uncharacterized protein.	0.771
A0A165CAI6	A0A165G6W6	Uncharacterized protein.	Uncharacterized protein.	0.404
A0A165CAI6	A0A165GAE8	Uncharacterized protein.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.781
A0A165CAI6	A0A165H923	Uncharacterized protein.	Transcription elongation factor 1 homolog; Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions. Belongs to the ELOF1 family.	0.485
A0A165CAI6	A0A165HHA6	Uncharacterized protein.	Transcription elongation factor SPT5; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.	0.781