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M896_121140 M896_121140 M896_110090 M896_110090 M896_100400 M896_100400 M896_090610 M896_090610 M896_091860 M896_091860 M896_080350 M896_080350 M896_050630 M896_050630 M896_051850 M896_051850 M896_040440 M896_040440 M896_041540 M896_041540 M896_020620 M896_020620 M896_021090 M896_021090 M896_011760 M896_011760 M896_120680 M896_120680 M896_120800 M896_120800 M896_120630 M896_120630 M896_100220 M896_100220 M896_090740 M896_090740 M896_120010 M896_120010 M896_120700 M896_120700 M896_090970 M896_090970 M896_080570 M896_080570 M896_110240 M896_110240 M896_090240 M896_090240 M896_070460 M896_070460 M896_081100 M896_081100 M896_091130 M896_091130 M896_050010 M896_050010 M896_080410 M896_080410 M896_060370 M896_060370 M896_050700 M896_050700 M896_051010 M896_051010 M896_051070 M896_051070 M896_051120 M896_051120 M896_070450 M896_070450 M896_050860 M896_050860 M896_052180 M896_052180 M896_060350 M896_060350 M896_040200 M896_040200 M896_040410 M896_040410 M896_051330 M896_051330 M896_050520 M896_050520 M896_051160 M896_051160 M896_051910 M896_051910 M896_030660 M896_030660 M896_051960 M896_051960 M896_041290 M896_041290 M896_020230 M896_020230 M896_021060 M896_021060 M896_021110 M896_021110 MCM7 MCM7 FEN1 FEN1 M896_030720 M896_030720 M896_010310 M896_010310 M896_031170 M896_031170 M896_011530 M896_011530 M896_021350 M896_021350 M896_012250 M896_012250 M896_021180 M896_021180 M896_021280 M896_021280 M896_021690 M896_021690 M896_011110 M896_011110 M896_012280 M896_012280 M896_011490 M896_011490
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
M896_121140Putative DNA mismatch repair enzyme. (671 aa)
M896_110090DNA repair flap endonuclease. (579 aa)
M896_100400Rad52 recombination DNA repair protein. (204 aa)
M896_090610Catalytic subunit of DNA primase. (286 aa)
M896_091860Cyclin-dependent protein kinase; Belongs to the protein kinase superfamily. (344 aa)
M896_080350BRCA-2_OB1 domain-containing protein. (497 aa)
M896_050630MutS-like mismatch repair ATPase. (967 aa)
M896_051850Putative DNA primase. (403 aa)
M896_040440DNA polymerase. (973 aa)
M896_041540DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (749 aa)
M896_020620Small subunit of replication factor C. (304 aa)
M896_021090Protein kinase domain-containing protein; Belongs to the PI3/PI4-kinase family. (1853 aa)
M896_011760Minichromosome maintenance protein; Belongs to the MCM family. (706 aa)
M896_120680Minichromosome maintenance protein; Belongs to the MCM family. (683 aa)
M896_120800Uncharacterized protein. (156 aa)
M896_120630Putative exonuclease. (382 aa)
M896_100220Subunit B of DNA polymerase delta. (424 aa)
M896_090740ERCC4-type nuclease. (756 aa)
M896_120010Uncharacterized protein. (162 aa)
M896_120700DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily. (332 aa)
M896_090970Uncharacterized protein. (228 aa)
M896_080570Rad50-like protein. (1245 aa)
M896_110240DNA helicase. (985 aa)
M896_090240DNA helicase; Belongs to the MCM family. (686 aa)
M896_070460Sld5 domain-containing protein. (174 aa)
M896_081100ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (737 aa)
M896_091130Brix domain-containing protein. (177 aa)
M896_050010Putative cyclin-dependent protein kinase; Belongs to the protein kinase superfamily. (152 aa)
M896_080410Cdc46/Mcm ATPase; Belongs to the MCM family. (562 aa)
M896_060370Single-stranded DNA-binding replication protein. (227 aa)
M896_050700Small subunit of replication factor C. (353 aa)
M896_051010Subunit B of DNA polymerase alpha. (420 aa)
M896_051070Subunit 2 of origin recognition complex. (252 aa)
M896_051120Rad14-like DNA excision repair protein. (208 aa)
M896_070450CDT1 domain-containing protein. (360 aa)
M896_050860Uncharacterized protein. (182 aa)
M896_052180DNA replication factor RFC1. (554 aa)
M896_060350DNA helicase; Belongs to the MCM family. (698 aa)
M896_040200Uncharacterized protein. (284 aa)
M896_040410Superfamily II DNA/RNA helicase. (703 aa)
M896_051330Nucleotide excision repair endonuclease Nef1. (187 aa)
M896_050520Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (575 aa)
M896_051160DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (1780 aa)
M896_051910Putative subunit of Mre11. (551 aa)
M896_030660Uncharacterized protein. (296 aa)
M896_051960Putative DNA replication protein kinase. (178 aa)
M896_041290DNA helicase; Belongs to the MCM family. (792 aa)
M896_020230AAA domain-containing protein. (285 aa)
M896_021060Rad3-like DNA-binding helicase. (675 aa)
M896_021110DNA helicase; Belongs to the MCM family. (709 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (694 aa)
FEN1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (345 aa)
M896_030720Cdc6-like protein. (341 aa)
M896_010310DNA repair protein Rad4. (402 aa)
M896_031170MutS-like mismatch repair ATPase. (716 aa)
M896_011530DNA polymerase. (952 aa)
M896_021350ERCC4 domain-containing protein. (489 aa)
M896_012250DNA polymerase alpha/epsilon-like protein. (401 aa)
M896_021180DNA ligase. (589 aa)
M896_021280Uncharacterized protein. (553 aa)
M896_021690C-terminal domain of replication factor C. (311 aa)
M896_011110Large subunit of replication factor C. (380 aa)
M896_012280Putative DNA mismatch repair protein. (577 aa)
M896_011490Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (265 aa)
Your Current Organism:
Ordospora colligata
NCBI taxonomy Id: 1354746
Other names: O. colligata OC4, Ordospora colligata OC4
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