STRINGSTRING
coaA coaA ARP73119.1 ARP73119.1 ARP73118.1 ARP73118.1 coaD coaD coaX coaX ARP68708.1 ARP68708.1 ARP68730.1 ARP68730.1 ARP68782.1 ARP68782.1 coaBC coaBC coaE coaE
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
coaAType I pantothenate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (329 aa)
ARP73119.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (383 aa)
ARP73118.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (236 aa)
coaDPantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (169 aa)
coaXType III pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (265 aa)
ARP68708.1Flavoprotein; Derived by automated computational analysis using gene prediction method: Protein Homology. (191 aa)
ARP68730.1Nucleoside triphosphate hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (233 aa)
ARP68782.1Flavoprotein; Derived by automated computational analysis using gene prediction method: Protein Homology. (177 aa)
coaBCPhosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (400 aa)
coaEdephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (209 aa)
Your Current Organism:
Streptomyces pluripotens
NCBI taxonomy Id: 1355015
Other names: DSM 42140, MCCC 1K00252, S. pluripotens, Streptomyces pluripotens Lee et al. 2014, Streptomyces sp. MUSC135, Streptomyces sp. MUSC137, strain MUSC 135
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