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dxs-3 dxs-3 ARP68910.1 ARP68910.1 ARP68911.1 ARP68911.1 ARP73898.1 ARP73898.1 ARP70008.1 ARP70008.1 ispD ispD ispF ispF ispE ispE ispH ispH ARP72252.1 ARP72252.1 dxr dxr ispG ispG dxs dxs hpnC hpnC hpnD hpnD ARP73275.1 ARP73275.1 ARP73276.1 ARP73276.1 ARP73278.1 ARP73278.1 ispG-2 ispG-2 dxs-2 dxs-2 ispG-3 ispG-3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
dxs-31-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (613 aa)
ARP68910.1Phytoene synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (339 aa)
ARP68911.1Phytoene dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (519 aa)
ARP73898.1Isorenieratene synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (582 aa)
ARP70008.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (409 aa)
ispDHypothetical protein; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). (250 aa)
ispF2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (177 aa)
ispE4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (297 aa)
ispH4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (338 aa)
ARP72252.1Polyprenyl synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FPP/GGPP synthase family. (379 aa)
dxr1-deoxy-D-xylulose-5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (423 aa)
ispG4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (385 aa)
dxs1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (642 aa)
hpnCSqualene synthase HpnC; Derived by automated computational analysis using gene prediction method: Protein Homology. (302 aa)
hpnDSqualene synthase HpnD; Derived by automated computational analysis using gene prediction method: Protein Homology. (320 aa)
ARP73275.1Phytoene dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (475 aa)
ARP73276.1Dimethylallyltranstransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FPP/GGPP synthase family. (377 aa)
ARP73278.11-hydroxy-2-methyl-2-butenyl 4-diphosphate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (213 aa)
ispG-24-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (371 aa)
dxs-21-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (632 aa)
ispG-34-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (379 aa)
Your Current Organism:
Streptomyces pluripotens
NCBI taxonomy Id: 1355015
Other names: DSM 42140, MCCC 1K00252, S. pluripotens, Streptomyces pluripotens Lee et al. 2014, Streptomyces sp. MUSC135, Streptomyces sp. MUSC137, strain MUSC 135
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