(58 nodes) Mixed, incl. PDZ domain, and Ezrin/radixin/moesin network (Caenorhabditis brenneri)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Cbn-dlg-1	CBN-DLG-1 protein; Belongs to the MAGUK family. (960 aa)
	CAEBREN_26160	Uncharacterized protein. (1532 aa)
	CAEBREN_29215	Uncharacterized protein. (148 aa)
	Cbn-tag-117	CBN-TAG-117 protein; Belongs to the MAGUK family. (658 aa)
	CAEBREN_07197	PDZ domain-containing protein. (530 aa)
	CAEBREN_05736	Uncharacterized protein. (101 aa)
	Cbn-pkc-2	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (745 aa)
	CAEBREN_21572	ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family. (1974 aa)
	Cbn-par-6	CBN-PAR-6 protein. (330 aa)
	CAEBREN_30723	PDZ domain-containing protein. (418 aa)
	Cbn-tom-1	CBN-TOM-1 protein. (1254 aa)
	Cbn-par-3	CBN-PAR-3 protein. (1424 aa)
	CAEBREN_07363	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (352 aa)
	Cbn-let-413	CBN-LET-413 protein. (711 aa)
	Cbn-mpz-1	CBN-MPZ-1 protein. (477 aa)
	CAEBREN_00545	Uncharacterized protein. (1768 aa)
	CAEBREN_16109	Uncharacterized protein. (173 aa)
	CAEBREN_18833	Protein kinase domain-containing protein. (378 aa)
	Cbn-lin-2	CBN-LIN-2 protein; Belongs to the MAGUK family. (1023 aa)
	CAEBREN_04874	Uncharacterized protein; Belongs to the MAGUK family. (571 aa)
	CAEBREN_32023	FERM domain-containing protein. (633 aa)
	CAEBREN_13414	Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (209 aa)
	Cbn-lgl-1	CBN-LGL-1 protein. (940 aa)
	CAEBREN_25877	Uncharacterized protein. (953 aa)
	Cbn-erm-1	CBN-ERM-1 protein. (563 aa)
	CAEBREN_26248	Guanylate kinase-like domain-containing protein. (140 aa)
	CAEBREN_17727	Tyrosine-protein kinase. (420 aa)
	CAEBREN_00623	Uncharacterized protein. (286 aa)
	CAEBREN_03918	Uncharacterized protein. (157 aa)
	CAEBREN_15875	Uncharacterized protein. (824 aa)
	CAEBREN_29442	Tyrosine-protein kinase. (395 aa)
	CAEBREN_12441	HECT domain-containing protein. (755 aa)
	CAEBREN_23111	Uncharacterized protein. (100 aa)
	CAEBREN_26347	Uncharacterized protein. (928 aa)
	CAEBREN_29602	FERM domain-containing protein. (516 aa)
	CAEBREN_31372	PRK domain-containing protein. (591 aa)
	CAEBREN_25970	Uncharacterized protein. (58 aa)
	CAEBREN_06982	PDZ domain-containing protein. (407 aa)
	CAEBREN_31692	ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family. (1382 aa)
	CAEBREN_30231	ANK_REP_REGION domain-containing protein. (610 aa)
	CAEBREN_18923	Uncharacterized protein. (214 aa)
	CAEBREN_10550	PDZ domain-containing protein. (407 aa)
	CAEBREN_06571	Uncharacterized protein. (515 aa)
	CAEBREN_25045	Uncharacterized protein. (420 aa)
	CAEBREN_12137	Tyrosine-protein kinase. (395 aa)
	CAEBREN_09838	Uncharacterized protein. (313 aa)
	CAEBREN_07177	Uncharacterized protein. (1256 aa)
	CAEBREN_10983	Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (217 aa)
	CAEBREN_11897	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (598 aa)
	CAEBREN_29199	Uncharacterized protein. (186 aa)
	CAEBREN_18360	Tyrosine-protein kinase. (399 aa)
	CAEBREN_05236	Tyrosine-protein kinase. (432 aa)
	CAEBREN_13945	Uncharacterized protein. (904 aa)
	CAEBREN_21521	Uncharacterized protein. (829 aa)
	CAEBREN_28393	PDZ domain-containing protein. (315 aa)
	CAEBREN_21359	Uncharacterized protein. (262 aa)
	CAEBREN_06624	Uncharacterized protein. (191 aa)
	CAEBREN_30665	Uncharacterized protein. (182 aa)

Your Current Organism:

Caenorhabditis brenneri

NCBI taxonomy Id: 135651
Other names: C. brenneri, Caenorhabditis CB5161, Caenorhabditis brenneri Sudhaus & Kiontke, 2007, Caenorhabditis n. sp. CB5161, Caenorhabditis sp. 1 CB5161, Caenorhabditis sp. 4 (CB5161, LKC28, SB129, SB280), Caenorhabditis sp. 4 (CE-II), Caenorhabditis sp. CB5161, Caenorhabditis sp. PB2801

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CAEBREN_00545	CAEBREN_04874	G0MVJ1	G0MYR5	Uncharacterized protein.	Uncharacterized protein; Belongs to the MAGUK family.	0.920
CAEBREN_00545	CAEBREN_05736	G0MVJ1	G0MGS9	Uncharacterized protein.	Uncharacterized protein.	0.845
CAEBREN_00545	CAEBREN_06571	G0MVJ1	G0P6S3	Uncharacterized protein.	Uncharacterized protein.	0.827
CAEBREN_00545	CAEBREN_06624	G0MVJ1	G0PMX8	Uncharacterized protein.	Uncharacterized protein.	0.604
CAEBREN_00545	CAEBREN_07197	G0MVJ1	G0MGR0	Uncharacterized protein.	PDZ domain-containing protein.	0.479
CAEBREN_00545	CAEBREN_07363	G0MVJ1	G0MQR6	Uncharacterized protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.873
CAEBREN_00545	CAEBREN_09838	G0MVJ1	G0P839	Uncharacterized protein.	Uncharacterized protein.	0.799
CAEBREN_00545	CAEBREN_11897	G0MVJ1	G0PDG0	Uncharacterized protein.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.871
CAEBREN_00545	CAEBREN_21521	G0MVJ1	G0PHX3	Uncharacterized protein.	Uncharacterized protein.	0.827
CAEBREN_00545	CAEBREN_21572	G0MVJ1	G0MJ18	Uncharacterized protein.	ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family.	0.717
CAEBREN_00545	CAEBREN_25045	G0MVJ1	G0P6S4	Uncharacterized protein.	Uncharacterized protein.	0.827
CAEBREN_00545	CAEBREN_26160	G0MVJ1	G0M9L6	Uncharacterized protein.	Uncharacterized protein.	0.530
CAEBREN_00545	CAEBREN_26248	G0MVJ1	G0NJL2	Uncharacterized protein.	Guanylate kinase-like domain-containing protein.	0.545
CAEBREN_00545	CAEBREN_26347	G0MVJ1	G0NUN4	Uncharacterized protein.	Uncharacterized protein.	0.540
CAEBREN_00545	CAEBREN_29215	G0MVJ1	G0MA25	Uncharacterized protein.	Uncharacterized protein.	0.479
CAEBREN_00545	CAEBREN_29602	G0MVJ1	G0NVJ3	Uncharacterized protein.	FERM domain-containing protein.	0.544
CAEBREN_00545	CAEBREN_30231	G0MVJ1	G0P207	Uncharacterized protein.	ANK_REP_REGION domain-containing protein.	0.717
CAEBREN_00545	CAEBREN_31692	G0MVJ1	G0P206	Uncharacterized protein.	ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family.	0.717
CAEBREN_00545	CAEBREN_32023	G0MVJ1	G0N2N7	Uncharacterized protein.	FERM domain-containing protein.	0.544
CAEBREN_00545	Cbn-dlg-1	G0MVJ1	G0M8Q3	Uncharacterized protein.	CBN-DLG-1 protein; Belongs to the MAGUK family.	0.572

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