(41 nodes) Fatty acid elongation, and Unsaturated fatty acid biosynthetic process network (Caenorhabditis brenneri)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CAEBREN_20261	Uncharacterized protein. (155 aa)
	CAEBREN_03099	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (203 aa)
	Cbn-elo-4	Elongation of very long chain fatty acids protein. (291 aa)
	CAEBREN_00022	Fucokinase domain-containing protein. (432 aa)
	CAEBREN_14431	Uncharacterized protein. (425 aa)
	Cbn-elo-9	Elongation of very long chain fatty acids protein. (286 aa)
	Cbn-elo-2	Elongation of very long chain fatty acids protein. (272 aa)
	CAEBREN_19665	Uncharacterized protein. (276 aa)
	CAEBREN_11647	Uncharacterized protein. (1047 aa)
	CAEBREN_11863	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (218 aa)
	Cbn-fat-5	CBN-FAT-5 protein; Belongs to the fatty acid desaturase type 1 family. (333 aa)
	Cbn-let-767	CBN-LET-767 protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (316 aa)
	CAEBREN_23772	FA_desaturase domain-containing protein. (444 aa)
	Cbn-ceeh-2	CBN-CEEH-2 protein. (337 aa)
	CAEBREN_29552	S5A_REDUCTASE domain-containing protein. (263 aa)
	Cbn-art-1	CBN-ART-1 protein. (308 aa)
	CAEBREN_11573	Methyltransf_21 domain-containing protein. (116 aa)
	CAEBREN_01700	Uncharacterized protein. (1337 aa)
	CAEBREN_23018	Methyltransf_21 domain-containing protein. (305 aa)
	CAEBREN_02563	FA_desaturase domain-containing protein. (399 aa)
	CAEBREN_08652	Uncharacterized protein. (376 aa)
	CAEBREN_28282	Uncharacterized protein; Belongs to the fatty acid desaturase type 1 family. (340 aa)
	CAEBREN_17271	FA_desaturase domain-containing protein. (447 aa)
	CAEBREN_30582	FA_desaturase domain-containing protein. (443 aa)
	Cbn-fat-3	CBN-FAT-3 protein. (443 aa)
	Cbn-elo-6	Elongation of very long chain fatty acids protein. (276 aa)
	Cbn-elo-5	Elongation of very long chain fatty acids protein. (272 aa)
	CAEBREN_03067	5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (201 aa)
	CAEBREN_23166	DUF148 domain-containing protein. (250 aa)
	CAEBREN_32484	Elongation of very long chain fatty acids protein. (318 aa)
	CAEBREN_24487	Uncharacterized protein. (376 aa)
	CAEBREN_23319	FA_desaturase domain-containing protein. (399 aa)
	CAEBREN_21751	Uncharacterized protein. (586 aa)
	CAEBREN_08726	Uncharacterized protein; Belongs to the fatty acid desaturase type 1 family. (340 aa)
	CAEBREN_12340	Elongation of very long chain fatty acids protein. (309 aa)
	Cbn-elo-1	Elongation of very long chain fatty acids protein. (289 aa)
	CAEBREN_04521	Elongation of very long chain fatty acids protein. (272 aa)
	CAEBREN_24344	Elongation of very long chain fatty acids protein. (276 aa)
	CAEBREN_07160	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (315 aa)
	Cbn-elo-3	Elongation of very long chain fatty acids protein. (318 aa)
	CAEBREN_05314	DUF148 domain-containing protein. (434 aa)

Your Current Organism:

Caenorhabditis brenneri

NCBI taxonomy Id: 135651
Other names: C. brenneri, Caenorhabditis CB5161, Caenorhabditis brenneri Sudhaus & Kiontke, 2007, Caenorhabditis n. sp. CB5161, Caenorhabditis sp. 1 CB5161, Caenorhabditis sp. 4 (CB5161, LKC28, SB129, SB280), Caenorhabditis sp. 4 (CE-II), Caenorhabditis sp. CB5161, Caenorhabditis sp. PB2801

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CAEBREN_00022	CAEBREN_32484	G0MKE9	G0P7W7	Fucokinase domain-containing protein.	Elongation of very long chain fatty acids protein.	0.563
CAEBREN_00022	Cbn-ceeh-2	G0MKE9	G0N8Y7	Fucokinase domain-containing protein.	CBN-CEEH-2 protein.	0.800
CAEBREN_00022	Cbn-elo-1	G0MKE9	G0PAR1	Fucokinase domain-containing protein.	Elongation of very long chain fatty acids protein.	0.447
CAEBREN_00022	Cbn-elo-3	G0MKE9	G0PGX9	Fucokinase domain-containing protein.	Elongation of very long chain fatty acids protein.	0.563
CAEBREN_00022	Cbn-elo-4	G0MKE9	G0MJZ9	Fucokinase domain-containing protein.	Elongation of very long chain fatty acids protein.	0.765
CAEBREN_00022	Cbn-elo-9	G0MKE9	G0MQF1	Fucokinase domain-containing protein.	Elongation of very long chain fatty acids protein.	0.580
CAEBREN_01700	CAEBREN_03099	G0NJA4	G0MGC6	Uncharacterized protein.	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]	0.703
CAEBREN_01700	CAEBREN_04521	G0NJA4	G0PBI1	Uncharacterized protein.	Elongation of very long chain fatty acids protein.	0.480
CAEBREN_01700	CAEBREN_05314	G0NJA4	G0PKV7	Uncharacterized protein.	DUF148 domain-containing protein.	0.466
CAEBREN_01700	CAEBREN_07160	G0NJA4	G0PED0	Uncharacterized protein.	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.535
CAEBREN_01700	CAEBREN_08726	G0NJA4	G0PAH2	Uncharacterized protein.	Uncharacterized protein; Belongs to the fatty acid desaturase type 1 family.	0.466
CAEBREN_01700	CAEBREN_11573	G0NJA4	G0NHW6	Uncharacterized protein.	Methyltransf_21 domain-containing protein.	0.522
CAEBREN_01700	CAEBREN_11863	G0NJA4	G0MY22	Uncharacterized protein.	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]	0.703
CAEBREN_01700	CAEBREN_12340	G0NJA4	G0PAQ9	Uncharacterized protein.	Elongation of very long chain fatty acids protein.	0.480
CAEBREN_01700	CAEBREN_14431	G0NJA4	G0MKW3	Uncharacterized protein.	Uncharacterized protein.	0.698
CAEBREN_01700	CAEBREN_17271	G0NJA4	G0NUI8	Uncharacterized protein.	FA_desaturase domain-containing protein.	0.538
CAEBREN_01700	CAEBREN_19665	G0NJA4	G0MRJ9	Uncharacterized protein.	Uncharacterized protein.	0.535
CAEBREN_01700	CAEBREN_20261	G0NJA4	G0M7M7	Uncharacterized protein.	Uncharacterized protein.	0.535
CAEBREN_01700	CAEBREN_21751	G0NJA4	G0PAH1	Uncharacterized protein.	Uncharacterized protein.	0.466
CAEBREN_01700	CAEBREN_23018	G0NJA4	G0NT28	Uncharacterized protein.	Methyltransf_21 domain-containing protein.	0.522

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