(74 nodes) cGMP biosynthetic process, and Cyclic nucleotide-dependent protein kinase activity network (Caenorhabditis brenneri)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CAEBREN_30737	Guanylate cyclase. (1128 aa)
	CAEBREN_28683	Guanylate cyclase domain-containing protein. (720 aa)
	CAEBREN_07219	Uncharacterized protein. (331 aa)
	Cbn-ets-5	CBN-ETS-5 protein. (209 aa)
	Cbn-gcy-4	Guanylate cyclase. (1122 aa)
	Cbn-gcy-36	CBN-GCY-36 protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (676 aa)
	CAEBREN_19286	Major sperm protein; Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. (404 aa)
	CAEBREN_15284	Nudix hydrolase domain-containing protein. (140 aa)
	CAEBREN_30389	Uncharacterized protein. (389 aa)
	CAEBREN_30483	ANF_receptor domain-containing protein. (415 aa)
	CAEBREN_31268	Guanylate cyclase. (770 aa)
	CAEBREN_30410	ANF_receptor domain-containing protein. (260 aa)
	CAEBREN_30901	Uncharacterized protein. (304 aa)
	CAEBREN_31888	ANF_receptor domain-containing protein. (571 aa)
	CAEBREN_05535	Uncharacterized protein. (658 aa)
	CAEBREN_31373	Uncharacterized protein. (726 aa)
	Cbn-rgs-5	CBN-RGS-5 protein. (491 aa)
	CAEBREN_14325	THAP-type domain-containing protein. (512 aa)
	CAEBREN_09843	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (343 aa)
	Cbn-gcy-25	Guanylate cyclase. (1047 aa)
	Cbn-gcy-34	CBN-GCY-34 protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (700 aa)
	Cbn-kin-2	CBN-KIN-2 protein. (366 aa)
	CAEBREN_23881	Uncharacterized protein. (338 aa)
	CAEBREN_24538	Uncharacterized protein. (340 aa)
	Cbn-aqp-12	CBN-AQP-12 protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (267 aa)
	Cbn-ttx-1	CBN-TTX-1 protein. (312 aa)
	Cbn-slo-1	CBN-SLO-1 protein. (1124 aa)
	CAEBREN_22481	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (670 aa)
	CAEBREN_09501	Tudor domain-containing protein. (551 aa)
	CAEBREN_29346	Uncharacterized protein. (1101 aa)
	Cbn-acy-3	CBN-ACY-3 protein. (1259 aa)
	Cbn-gcy-37	CBN-GCY-37 protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (704 aa)
	CAEBREN_30054	Uncharacterized protein. (251 aa)
	Cbn-gcy-12	Guanylate cyclase. (1689 aa)
	Cbn-kin-1	CBN-KIN-1 protein; Belongs to the protein kinase superfamily. (379 aa)
	CAEBREN_28650	Uncharacterized protein. (58 aa)
	CAEBREN_30000	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (299 aa)
	CAEBREN_25785	Uncharacterized protein. (322 aa)
	CAEBREN_31325	Uncharacterized protein. (456 aa)
	CAEBREN_32015	Uncharacterized protein. (49 aa)
	CAEBREN_31720	Guanylate cyclase domain-containing protein. (104 aa)
	CAEBREN_02821	ANF_receptor domain-containing protein. (183 aa)
	Cbn-gcy-33	CBN-GCY-33 protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (961 aa)
	Cbn-gcy-7	Guanylate cyclase. (1113 aa)
	Cbn-gcy-22	Guanylate cyclase. (1064 aa)
	CAEBREN_24032	Guanylate cyclase. (1061 aa)
	Cbn-gcy-3	Guanylate cyclase. (2236 aa)
	CAEBREN_08948	Guanylate cyclase. (817 aa)
	CAEBREN_12449	Guanylate cyclase. (821 aa)
	CAEBREN_26417	Guanylate cyclase. (1133 aa)
	CAEBREN_09776	Guanylate cyclase. (1039 aa)
	Cbn-egl-4	cGMP-dependent protein kinase. (777 aa)
	Cbn-gcy-8	CBN-GCY-8 protein. (523 aa)
	CAEBREN_32592	Guanylate cyclase domain-containing protein. (344 aa)
	CAEBREN_17811	Uncharacterized protein. (95 aa)
	Cbn-gcy-17	Guanylate cyclase. (1319 aa)
	CAEBREN_04714	Guanylate cyclase. (962 aa)
	Cbn-srtx-1	CBN-SRTX-1 protein. (355 aa)
	CAEBREN_29111	ANF_receptor domain-containing protein. (246 aa)
	CAEBREN_31371	ANF_receptor domain-containing protein. (562 aa)
	CAEBREN_26379	Uncharacterized protein. (370 aa)
	CAEBREN_22402	Guanylate cyclase. (1043 aa)
	CAEBREN_02344	Uncharacterized protein. (505 aa)
	CAEBREN_06706	Uncharacterized protein; Belongs to the protein kinase superfamily. (313 aa)
	CAEBREN_02442	Uncharacterized protein. (389 aa)
	CAEBREN_29824	HNOB domain-containing protein. (231 aa)
	CAEBREN_28377	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (686 aa)
	CAEBREN_06877	ANF_receptor domain-containing protein. (577 aa)
	CAEBREN_28904	Uncharacterized protein. (428 aa)
	CAEBREN_31769	Guanylate cyclase. (1280 aa)
	CAEBREN_06514	Uncharacterized protein. (112 aa)
	Cbn-gcy-32	CBN-GCY-32 protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (615 aa)
	CAEBREN_29583	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (222 aa)
	CAEBREN_21876	Uncharacterized protein. (365 aa)

Your Current Organism:

Caenorhabditis brenneri

NCBI taxonomy Id: 135651
Other names: C. brenneri, Caenorhabditis CB5161, Caenorhabditis brenneri Sudhaus & Kiontke, 2007, Caenorhabditis n. sp. CB5161, Caenorhabditis sp. 1 CB5161, Caenorhabditis sp. 4 (CB5161, LKC28, SB129, SB280), Caenorhabditis sp. 4 (CE-II), Caenorhabditis sp. CB5161, Caenorhabditis sp. PB2801

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CAEBREN_02344	CAEBREN_05535	G0PF35	G0MPB9	Uncharacterized protein.	Uncharacterized protein.	0.537
CAEBREN_02344	CAEBREN_15284	G0PF35	G0MJ15	Uncharacterized protein.	Nudix hydrolase domain-containing protein.	0.649
CAEBREN_02344	CAEBREN_21876	G0PF35	G0PP04	Uncharacterized protein.	Uncharacterized protein.	0.638
CAEBREN_02344	CAEBREN_22481	G0PF35	G0N1C2	Uncharacterized protein.	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	0.652
CAEBREN_02344	CAEBREN_24032	G0PF35	G0NL65	Uncharacterized protein.	Guanylate cyclase.	0.654
CAEBREN_02344	CAEBREN_31373	G0PF35	G0MPC0	Uncharacterized protein.	Uncharacterized protein.	0.427
CAEBREN_02442	CAEBREN_28904	G0PGP8	G0PKB6	Uncharacterized protein.	Uncharacterized protein.	0.633
CAEBREN_02442	CAEBREN_31769	G0PGP8	G0PKB7	Uncharacterized protein.	Guanylate cyclase.	0.633
CAEBREN_02442	Cbn-gcy-12	G0PGP8	G0NAX7	Uncharacterized protein.	Guanylate cyclase.	0.633
CAEBREN_02821	CAEBREN_05535	G0NG56	G0MPB9	ANF_receptor domain-containing protein.	Uncharacterized protein.	0.859
CAEBREN_02821	CAEBREN_06514	G0NG56	G0PL75	ANF_receptor domain-containing protein.	Uncharacterized protein.	0.527
CAEBREN_02821	CAEBREN_06706	G0NG56	G0PGP4	ANF_receptor domain-containing protein.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.527
CAEBREN_02821	CAEBREN_07219	G0NG56	G0M7U5	ANF_receptor domain-containing protein.	Uncharacterized protein.	0.445
CAEBREN_02821	CAEBREN_09843	G0NG56	G0MQR1	ANF_receptor domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.445
CAEBREN_02821	CAEBREN_15284	G0NG56	G0MJ15	ANF_receptor domain-containing protein.	Nudix hydrolase domain-containing protein.	0.894
CAEBREN_02821	CAEBREN_21876	G0NG56	G0PP04	ANF_receptor domain-containing protein.	Uncharacterized protein.	0.651
CAEBREN_02821	CAEBREN_26379	G0NG56	G0PCS3	ANF_receptor domain-containing protein.	Uncharacterized protein.	0.524
CAEBREN_02821	CAEBREN_28650	G0NG56	G0NCH4	ANF_receptor domain-containing protein.	Uncharacterized protein.	0.445
CAEBREN_02821	CAEBREN_29346	G0NG56	G0N452	ANF_receptor domain-containing protein.	Uncharacterized protein.	0.527
CAEBREN_02821	CAEBREN_30054	G0NG56	G0N7L0	ANF_receptor domain-containing protein.	Uncharacterized protein.	0.513

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