(54 nodes) Mixed, incl. Transmembrane receptor protein tyrosine kinase activity, and Interleukin-2 family signaling network (Caenorhabditis brenneri)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CAEBREN_03763	Uncharacterized protein. (874 aa)
	CAEBREN_21305	Protein kinase domain-containing protein. (382 aa)
	Cbn-kin-32	CBN-KIN-32 protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (866 aa)
	Cbn-aap-1	CBN-AAP-1 protein. (517 aa)
	CAEBREN_25145	Uncharacterized protein. (941 aa)
	CAEBREN_18868	Uncharacterized protein. (1094 aa)
	Cbn-abl-1	Tyrosine-protein kinase. (1261 aa)
	CAEBREN_08989	Uncharacterized protein. (423 aa)
	Cbn-kal-1	CBN-KAL-1 protein. (716 aa)
	CAEBREN_31042	Uncharacterized protein; Belongs to the heparin-binding growth factors family. (376 aa)
	CAEBREN_29800	Uncharacterized protein. (71 aa)
	CAEBREN_00204	Uncharacterized protein. (333 aa)
	CAEBREN_30239	Uncharacterized protein. (436 aa)
	CAEBREN_10086	Tyrosine-protein kinase. (525 aa)
	CAEBREN_08526	Fibrinogen C-terminal domain-containing protein. (511 aa)
	Cbn-sos-1	CBN-SOS-1 protein. (1459 aa)
	CAEBREN_13567	Protein kinase domain-containing protein. (395 aa)
	Cbn-age-1	CBN-AGE-1 protein; Belongs to the PI3/PI4-kinase family. (1144 aa)
	Cbn-sem-5	CBN-SEM-5 protein. (230 aa)
	CAEBREN_31173	Uncharacterized protein. (269 aa)
	CAEBREN_08135	Protein kinase domain-containing protein. (292 aa)
	CAEBREN_11030	Uncharacterized protein. (1079 aa)
	CAEBREN_14607	Protein kinase domain-containing protein. (716 aa)
	CAEBREN_18348	Uncharacterized protein. (815 aa)
	Cbn-ced-2	CBN-CED-2 protein. (277 aa)
	CAEBREN_30669	Uncharacterized protein. (554 aa)
	CAEBREN_17226	Uncharacterized protein. (600 aa)
	Cbn-kin-16	CBN-KIN-16 protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (514 aa)
	CAEBREN_03837	Protein kinase domain-containing protein. (460 aa)
	CAEBREN_13701	Uncharacterized protein. (374 aa)
	CAEBREN_08755	Uncharacterized protein. (937 aa)
	CAEBREN_06464	Receptor protein-tyrosine kinase. (1268 aa)
	CAEBREN_31101	Uncharacterized protein; Belongs to the glycosyl hydrolase 1 family. (390 aa)
	CAEBREN_10578	Protein kinase domain-containing protein. (241 aa)
	CAEBREN_15821	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (464 aa)
	CAEBREN_12244	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (460 aa)
	CAEBREN_19981	Protein kinase domain-containing protein. (355 aa)
	CAEBREN_10270	Protein kinase domain-containing protein. (246 aa)
	Cbn-rgef-1	CBN-RGEF-1 protein. (656 aa)
	CAEBREN_02023	Uncharacterized protein. (339 aa)
	CAEBREN_11311	IRS-type PTB domain-containing protein. (300 aa)
	CAEBREN_30892	Uncharacterized protein; Belongs to the glycosyl hydrolase 1 family. (479 aa)
	Cbn-tag-83	CBN-TAG-83 protein. (240 aa)
	CAEBREN_32133	Uncharacterized protein. (517 aa)
	CAEBREN_04712	Tyrosine-protein kinase. (525 aa)
	CAEBREN_28982	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (884 aa)
	CAEBREN_29894	Uncharacterized protein. (1897 aa)
	CAEBREN_03470	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1178 aa)
	Cbn-rol-3	CBN-ROL-3 protein. (347 aa)
	CAEBREN_28668	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (819 aa)
	CAEBREN_28467	SH2 domain-containing protein. (293 aa)
	CAEBREN_31450	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (669 aa)
	CAEBREN_32241	Protein kinase domain-containing protein. (528 aa)
	Cbn-soc-1	CBN-SOC-1 protein. (464 aa)

Your Current Organism:

Caenorhabditis brenneri

NCBI taxonomy Id: 135651
Other names: C. brenneri, Caenorhabditis CB5161, Caenorhabditis brenneri Sudhaus & Kiontke, 2007, Caenorhabditis n. sp. CB5161, Caenorhabditis sp. 1 CB5161, Caenorhabditis sp. 4 (CB5161, LKC28, SB129, SB280), Caenorhabditis sp. 4 (CE-II), Caenorhabditis sp. CB5161, Caenorhabditis sp. PB2801

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CAEBREN_00204	CAEBREN_03470	G0MM45	G0PIY2	Uncharacterized protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.712
CAEBREN_00204	CAEBREN_03763	G0MM45	G0M8L0	Uncharacterized protein.	Uncharacterized protein.	0.851
CAEBREN_00204	CAEBREN_03837	G0MM45	G0NAH3	Uncharacterized protein.	Protein kinase domain-containing protein.	0.757
CAEBREN_00204	CAEBREN_04712	G0MM45	G0P982	Uncharacterized protein.	Tyrosine-protein kinase.	0.773
CAEBREN_00204	CAEBREN_06464	G0MM45	G0NEC2	Uncharacterized protein.	Receptor protein-tyrosine kinase.	0.995
CAEBREN_00204	CAEBREN_08135	G0MM45	G0MXE4	Uncharacterized protein.	Protein kinase domain-containing protein.	0.863
CAEBREN_00204	CAEBREN_08526	G0MM45	G0MQM0	Uncharacterized protein.	Fibrinogen C-terminal domain-containing protein.	0.580
CAEBREN_00204	CAEBREN_08755	G0MM45	G0NE97	Uncharacterized protein.	Uncharacterized protein.	0.915
CAEBREN_00204	CAEBREN_08989	G0MM45	G0MI93	Uncharacterized protein.	Uncharacterized protein.	0.860
CAEBREN_00204	CAEBREN_10086	G0MM45	G0MNP2	Uncharacterized protein.	Tyrosine-protein kinase.	0.773
CAEBREN_00204	CAEBREN_10270	G0MM45	G0NN50	Uncharacterized protein.	Protein kinase domain-containing protein.	0.757
CAEBREN_00204	CAEBREN_10578	G0MM45	G0NMR8	Uncharacterized protein.	Protein kinase domain-containing protein.	0.757
CAEBREN_00204	CAEBREN_11030	G0MM45	G0MZW9	Uncharacterized protein.	Uncharacterized protein.	0.601
CAEBREN_00204	CAEBREN_11311	G0MM45	G0NWA9	Uncharacterized protein.	IRS-type PTB domain-containing protein.	0.442
CAEBREN_00204	CAEBREN_12244	G0MM45	G0NN34	Uncharacterized protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.757
CAEBREN_00204	CAEBREN_13567	G0MM45	G0MTP6	Uncharacterized protein.	Protein kinase domain-containing protein.	0.969
CAEBREN_00204	CAEBREN_13701	G0MM45	G0NE32	Uncharacterized protein.	Uncharacterized protein.	0.596
CAEBREN_00204	CAEBREN_14607	G0MM45	G0N0K7	Uncharacterized protein.	Protein kinase domain-containing protein.	0.863
CAEBREN_00204	CAEBREN_15821	G0MM45	G0NN30	Uncharacterized protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.757
CAEBREN_00204	CAEBREN_17226	G0MM45	G0N7R0	Uncharacterized protein.	Uncharacterized protein.	0.900

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