(12 nodes) Mixed, incl. SUMOylation of immune response proteins, and SUMO activating enzyme complex network (Caenorhabditis brenneri)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

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protein homology

Your Input:
	CAEBREN_01082	UBIQUITIN_CONJUGAT_2 domain-containing protein. (200 aa)
	CAEBREN_11427	UBIQUITIN_CONJUGAT_2 domain-containing protein. (205 aa)
	CAEBREN_09907	Uncharacterized protein. (149 aa)
	CAEBREN_04083	Uncharacterized protein. (576 aa)
	Cbn-uba-2	SUMO-activating enzyme subunit; Belongs to the ubiquitin-activating E1 family. (607 aa)
	CAEBREN_18819	Uncharacterized protein. (886 aa)
	Cbn-ran-1	GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (215 aa)
	CAEBREN_23438	UBIQUITIN_CONJUGAT_2 domain-containing protein. (226 aa)
	Cbn-aos-1	CBN-AOS-1 protein. (353 aa)
	CAEBREN_02901	Ubiquitin-like domain-containing protein. (91 aa)
	CAEBREN_15266	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (166 aa)
	CAEBREN_03638	Uncharacterized protein. (592 aa)

Your Current Organism:

Caenorhabditis brenneri

NCBI taxonomy Id: 135651
Other names: C. brenneri, Caenorhabditis CB5161, Caenorhabditis brenneri Sudhaus & Kiontke, 2007, Caenorhabditis n. sp. CB5161, Caenorhabditis sp. 1 CB5161, Caenorhabditis sp. 4 (CB5161, LKC28, SB129, SB280), Caenorhabditis sp. 4 (CE-II), Caenorhabditis sp. CB5161, Caenorhabditis sp. PB2801

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CAEBREN_01082	CAEBREN_02901	G0M8H4	G0NFG5	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Ubiquitin-like domain-containing protein.	0.996
CAEBREN_01082	CAEBREN_03638	G0M8H4	G0PKS9	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Uncharacterized protein.	0.710
CAEBREN_01082	CAEBREN_04083	G0M8H4	G0MGE2	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Uncharacterized protein.	0.862
CAEBREN_01082	CAEBREN_09907	G0M8H4	G0MGE1	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Uncharacterized protein.	0.862
CAEBREN_01082	CAEBREN_11427	G0M8H4	G0M8H9	UBIQUITIN_CONJUGAT_2 domain-containing protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein.	0.884
CAEBREN_01082	CAEBREN_18819	G0M8H4	G0MKR3	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Uncharacterized protein.	0.966
CAEBREN_01082	CAEBREN_23438	G0M8H4	G0MX21	UBIQUITIN_CONJUGAT_2 domain-containing protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein.	0.507
CAEBREN_01082	Cbn-aos-1	G0M8H4	G0N937	UBIQUITIN_CONJUGAT_2 domain-containing protein.	CBN-AOS-1 protein.	0.960
CAEBREN_01082	Cbn-ran-1	G0M8H4	G0MKZ4	UBIQUITIN_CONJUGAT_2 domain-containing protein.	GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	0.854
CAEBREN_01082	Cbn-uba-2	G0M8H4	G0MJ42	UBIQUITIN_CONJUGAT_2 domain-containing protein.	SUMO-activating enzyme subunit; Belongs to the ubiquitin-activating E1 family.	0.979
CAEBREN_02901	CAEBREN_01082	G0NFG5	G0M8H4	Ubiquitin-like domain-containing protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein.	0.996
CAEBREN_02901	CAEBREN_03638	G0NFG5	G0PKS9	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.440
CAEBREN_02901	CAEBREN_04083	G0NFG5	G0MGE2	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.925
CAEBREN_02901	CAEBREN_09907	G0NFG5	G0MGE1	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.925
CAEBREN_02901	CAEBREN_11427	G0NFG5	G0M8H9	Ubiquitin-like domain-containing protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein.	0.984
CAEBREN_02901	CAEBREN_15266	G0NFG5	G0P4M8	Ubiquitin-like domain-containing protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.996
CAEBREN_02901	CAEBREN_18819	G0NFG5	G0MKR3	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.981
CAEBREN_02901	CAEBREN_23438	G0NFG5	G0MX21	Ubiquitin-like domain-containing protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein.	0.996
CAEBREN_02901	Cbn-aos-1	G0NFG5	G0N937	Ubiquitin-like domain-containing protein.	CBN-AOS-1 protein.	0.995
CAEBREN_02901	Cbn-ran-1	G0NFG5	G0MKZ4	Ubiquitin-like domain-containing protein.	GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	0.747

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