(43 nodes) Mixed, incl. Cortical actin cytoskeleton organization, and Formin, FH2 domain network (Caenorhabditis brenneri)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CAEBREN_10405	Uncharacterized protein; Belongs to the profilin family. (101 aa)
	CAEBREN_00889	Uncharacterized protein; Belongs to the profilin family. (117 aa)
	Cbn-pfn-2	Profilin; Belongs to the profilin family. (131 aa)
	Cbn-cyk-1	CBN-CYK-1 protein. (1444 aa)
	CAEBREN_23287	PH domain-containing protein. (1748 aa)
	Cbn-fozi-1	CBN-FOZI-1 protein. (757 aa)
	CAEBREN_21624	Uncharacterized protein. (267 aa)
	CAEBREN_16938	Uncharacterized protein. (192 aa)
	CAEBREN_10967	Uncharacterized protein. (166 aa)
	Cbn-mrck-1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1590 aa)
	Cbn-inft-1	CBN-INFT-1 protein. (861 aa)
	CAEBREN_08737	PH domain-containing protein. (993 aa)
	Cbn-ani-3	CBN-ANI-3 protein. (777 aa)
	CAEBREN_18419	Uncharacterized protein. (258 aa)
	CAEBREN_20440	Uncharacterized protein. (806 aa)
	CAEBREN_05785	Uncharacterized protein. (502 aa)
	CAEBREN_31493	PH domain-containing protein. (1145 aa)
	CAEBREN_02564	Uncharacterized protein. (702 aa)
	Cbn-pfn-3	Profilin; Belongs to the profilin family. (126 aa)
	CAEBREN_32827	Uncharacterized protein. (376 aa)
	CAEBREN_29004	FH2 domain-containing protein. (893 aa)
	CAEBREN_16594	Drf_GBD domain-containing protein. (177 aa)
	Cbn-daam-1	CBN-DAAM-1 protein. (787 aa)
	CAEBREN_06732	Uncharacterized protein. (247 aa)
	CAEBREN_07679	Uncharacterized protein. (331 aa)
	CAEBREN_30880	Uncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1043 aa)
	CAEBREN_30352	Protein kinase domain-containing protein. (119 aa)
	CAEBREN_21045	Uncharacterized protein. (1287 aa)
	CAEBREN_11480	THUMP domain-containing protein. (391 aa)
	CAEBREN_21655	Uncharacterized protein. (331 aa)
	Cbn-frl-1	CBN-FRL-1 protein. (1188 aa)
	CAEBREN_16586	CNH domain-containing protein. (248 aa)
	CAEBREN_13043	Uncharacterized protein. (1287 aa)
	CAEBREN_17480	Uncharacterized protein. (136 aa)
	CAEBREN_10807	Uncharacterized protein. (234 aa)
	CAEBREN_21935	Uncharacterized protein. (240 aa)
	CAEBREN_11630	Uncharacterized protein. (672 aa)
	CAEBREN_21448	PH domain-containing protein. (993 aa)
	CAEBREN_28912	Drf_GBD domain-containing protein. (218 aa)
	CAEBREN_30939	Uncharacterized protein. (283 aa)
	CAEBREN_29365	Uncharacterized protein. (388 aa)
	CAEBREN_28278	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (250 aa)
	CAEBREN_32354	FH2 domain-containing protein. (556 aa)

Your Current Organism:

Caenorhabditis brenneri

NCBI taxonomy Id: 135651
Other names: C. brenneri, Caenorhabditis CB5161, Caenorhabditis brenneri Sudhaus & Kiontke, 2007, Caenorhabditis n. sp. CB5161, Caenorhabditis sp. 1 CB5161, Caenorhabditis sp. 4 (CB5161, LKC28, SB129, SB280), Caenorhabditis sp. 4 (CE-II), Caenorhabditis sp. CB5161, Caenorhabditis sp. PB2801

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CAEBREN_00889	CAEBREN_06732	G0M8N0	G0NCT6	Uncharacterized protein; Belongs to the profilin family.	Uncharacterized protein.	0.725
CAEBREN_00889	CAEBREN_07679	G0M8N0	G0NH46	Uncharacterized protein; Belongs to the profilin family.	Uncharacterized protein.	0.638
CAEBREN_00889	CAEBREN_10807	G0M8N0	G0PD36	Uncharacterized protein; Belongs to the profilin family.	Uncharacterized protein.	0.725
CAEBREN_00889	CAEBREN_10967	G0M8N0	G0MXH9	Uncharacterized protein; Belongs to the profilin family.	Uncharacterized protein.	0.641
CAEBREN_00889	CAEBREN_11480	G0M8N0	G0NU62	Uncharacterized protein; Belongs to the profilin family.	THUMP domain-containing protein.	0.490
CAEBREN_00889	CAEBREN_11630	G0M8N0	G0PDF1	Uncharacterized protein; Belongs to the profilin family.	Uncharacterized protein.	0.638
CAEBREN_00889	CAEBREN_16594	G0M8N0	G0NBK5	Uncharacterized protein; Belongs to the profilin family.	Drf_GBD domain-containing protein.	0.794
CAEBREN_00889	CAEBREN_16938	G0M8N0	G0MR45	Uncharacterized protein; Belongs to the profilin family.	Uncharacterized protein.	0.691
CAEBREN_00889	CAEBREN_17480	G0M8N0	G0PAI8	Uncharacterized protein; Belongs to the profilin family.	Uncharacterized protein.	0.725
CAEBREN_00889	CAEBREN_18419	G0M8N0	G0N2T5	Uncharacterized protein; Belongs to the profilin family.	Uncharacterized protein.	0.794
CAEBREN_00889	CAEBREN_21624	G0M8N0	G0MR40	Uncharacterized protein; Belongs to the profilin family.	Uncharacterized protein.	0.691
CAEBREN_00889	CAEBREN_21655	G0M8N0	G0P184	Uncharacterized protein; Belongs to the profilin family.	Uncharacterized protein.	0.638
CAEBREN_00889	CAEBREN_21935	G0M8N0	G0PD51	Uncharacterized protein; Belongs to the profilin family.	Uncharacterized protein.	0.794
CAEBREN_00889	CAEBREN_28912	G0M8N0	G0PFQ5	Uncharacterized protein; Belongs to the profilin family.	Drf_GBD domain-containing protein.	0.794
CAEBREN_00889	CAEBREN_29004	G0M8N0	G0N981	Uncharacterized protein; Belongs to the profilin family.	FH2 domain-containing protein.	0.808
CAEBREN_00889	CAEBREN_30939	G0M8N0	G0PGP0	Uncharacterized protein; Belongs to the profilin family.	Uncharacterized protein.	0.638
CAEBREN_00889	CAEBREN_32354	G0M8N0	G0PNF4	Uncharacterized protein; Belongs to the profilin family.	FH2 domain-containing protein.	0.808
CAEBREN_00889	CAEBREN_32827	G0M8N0	G0N8I1	Uncharacterized protein; Belongs to the profilin family.	Uncharacterized protein.	0.725
CAEBREN_00889	Cbn-cyk-1	G0M8N0	G0MEQ9	Uncharacterized protein; Belongs to the profilin family.	CBN-CYK-1 protein.	0.747
CAEBREN_00889	Cbn-daam-1	G0M8N0	G0NBK6	Uncharacterized protein; Belongs to the profilin family.	CBN-DAAM-1 protein.	0.794

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