(112 nodes) Kinase regulator activity network (Caenorhabditis brenneri)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CAEBREN_03315	Raptor_N domain-containing protein. (1768 aa)
	Cbn-icp-1	CBN-ICP-1 protein. (650 aa)
	CAEBREN_21775	Uncharacterized protein. (253 aa)
	CAEBREN_31794	ANK_REP_REGION domain-containing protein. (452 aa)
	CAEBREN_21403	ANK_REP_REGION domain-containing protein. (1468 aa)
	CAEBREN_24328	Uncharacterized protein; Belongs to the cyclin family. (391 aa)
	CAEBREN_32306	RICTOR_N domain-containing protein. (763 aa)
	CAEBREN_30436	RICTOR_N domain-containing protein. (727 aa)
	CAEBREN_00712	RICTOR_V domain-containing protein. (748 aa)
	Cbn-cyd-1	CBN-CYD-1 protein; Belongs to the cyclin family. (418 aa)
	CAEBREN_02046	Uncharacterized protein. (330 aa)
	CAEBREN_02963	WD_REPEATS_REGION domain-containing protein. (362 aa)
	CAEBREN_19031	Uncharacterized protein. (474 aa)
	CAEBREN_06299	CYCLIN domain-containing protein; Belongs to the cyclin family. (251 aa)
	Cbn-kin-10	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (229 aa)
	Cbn-cyb-3	CBN-CYB-3 protein; Belongs to the cyclin family. (379 aa)
	CAEBREN_08072	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (103 aa)
	CAEBREN_14236	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (482 aa)
	Cbn-mnat-1	CBN-MNAT-1 protein. (310 aa)
	CAEBREN_05184	Uncharacterized protein. (570 aa)
	CAEBREN_18892	Uncharacterized protein. (402 aa)
	CAEBREN_12491	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (532 aa)
	CAEBREN_28173	Uncharacterized protein; Belongs to the cyclin family. (501 aa)
	CAEBREN_17051	Uncharacterized protein. (335 aa)
	CAEBREN_00250	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (357 aa)
	CAEBREN_08972	SH2 domain-containing protein. (193 aa)
	CAEBREN_06732	Uncharacterized protein. (247 aa)
	Cbn-vhp-1	CBN-VHP-1 protein. (634 aa)
	CAEBREN_03837	Protein kinase domain-containing protein. (460 aa)
	CAEBREN_19694	Uncharacterized protein. (368 aa)
	CAEBREN_03595	Uncharacterized protein. (145 aa)
	CAEBREN_18552	Uncharacterized protein. (427 aa)
	CAEBREN_14796	Uncharacterized protein. (337 aa)
	CAEBREN_23689	Uncharacterized protein. (253 aa)
	Cbn-hen-1	CBN-HEN-1 protein. (113 aa)
	Cbn-dnj-7	CBN-DNJ-7 protein. (495 aa)
	CAEBREN_02111	Uncharacterized protein; Belongs to the eukaryotic ribosomal protein P1/P2 family. (111 aa)
	CAEBREN_10104	DUF727 domain-containing protein. (255 aa)
	CAEBREN_01485	Uncharacterized protein. (107 aa)
	Cbn-cit-1.1	CBN-CIT-1.1 protein. (240 aa)
	Cbn-cit-1.2	CBN-CIT-1.2 protein. (590 aa)
	CAEBREN_29643	Uncharacterized protein. (241 aa)
	CAEBREN_19886	DUF727 domain-containing protein. (193 aa)
	CAEBREN_20846	Cyclin N-terminal domain-containing protein. (310 aa)
	Cbn-dbl-1	CBN-DBL-1 protein. (371 aa)
	Cbn-sek-1	CBN-SEK-1 protein; Belongs to the protein kinase superfamily. (341 aa)
	Cbn-kin-2	CBN-KIN-2 protein. (366 aa)
	CAEBREN_11449	Uncharacterized protein. (261 aa)
	CAEBREN_05829	DUF727 domain-containing protein. (215 aa)
	CAEBREN_19173	Protein kinase domain-containing protein. (1501 aa)
	CAEBREN_00673	CYCLIN domain-containing protein; Belongs to the cyclin family. (309 aa)
	Cbn-wrm-1	CBN-WRM-1 protein. (843 aa)
	CAEBREN_31657	Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. (547 aa)
	CAEBREN_09292	Uncharacterized protein; Belongs to the cyclin family. (432 aa)
	CAEBREN_16235	Uncharacterized protein; Belongs to the cyclin family. (499 aa)
	Cbn-aakg-2	CBN-AAKG-2 protein. (422 aa)
	Cbn-cye-1	CBN-CYE-1 protein; Belongs to the cyclin family. (455 aa)
	CAEBREN_00019	INCENP_ARK-bind domain-containing protein. (297 aa)
	CAEBREN_11672	Uncharacterized protein. (714 aa)
	Cbn-aap-1	CBN-AAP-1 protein. (517 aa)
	CAEBREN_21080	Uncharacterized protein. (199 aa)
	CAEBREN_17299	UDENN FLCN/SMCR8-type domain-containing protein. (513 aa)
	Cbn-cdka-1	Cyclin-dependent kinase 5 activator. (366 aa)
	Cbn-tir-1	CBN-TIR-1 protein. (967 aa)
	CAEBREN_21367	Uncharacterized protein. (429 aa)
	CAEBREN_06979	Uncharacterized protein. (245 aa)
	CAEBREN_01467	Uncharacterized protein. (355 aa)
	Cbn-tap-1	CBN-TAP-1 protein. (393 aa)
	CAEBREN_19506	Uncharacterized protein. (72 aa)
	CAEBREN_05564	Uncharacterized protein. (243 aa)
	Cbn-mop-25.1	CBN-MOP-25.1 protein. (761 aa)
	CAEBREN_06890	Uncharacterized protein. (239 aa)
	Cbn-clc-3	CBN-CLC-3 protein. (222 aa)
	Cbn-aakg-4	CBN-AAKG-4 protein. (464 aa)
	Cbn-aakg-3	CBN-AAKG-3 protein. (376 aa)
	CAEBREN_29276	Uncharacterized protein. (193 aa)
	CAEBREN_02961	Uncharacterized protein; Belongs to the eukaryotic ribosomal protein P1/P2 family. (128 aa)
	Cbn-cki-1	CBN-CKI-1 protein. (187 aa)
	CAEBREN_29266	RICTOR_V domain-containing protein. (754 aa)
	CAEBREN_32546	Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. (547 aa)
	CAEBREN_09421	TGF_BETA_2 domain-containing protein. (370 aa)
	Cbn-daf-15	CBN-DAF-15 protein. (1768 aa)
	CAEBREN_14453	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (103 aa)
	CAEBREN_29750	Uncharacterized protein. (602 aa)
	CAEBREN_14487	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (418 aa)
	CAEBREN_10807	Uncharacterized protein. (234 aa)
	CAEBREN_09216	Uncharacterized protein; Belongs to the eukaryotic ribosomal protein P1/P2 family. (111 aa)
	CAEBREN_20731	Uncharacterized protein. (279 aa)
	Cbn-nsy-1	CBN-NSY-1 protein. (1501 aa)
	CAEBREN_20813	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (98 aa)
	CAEBREN_08050	Uncharacterized protein. (713 aa)
	CAEBREN_30006	INCENP_ARK-bind domain-containing protein. (629 aa)
	Cbn-tpa-1	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (706 aa)
	CAEBREN_32133	Uncharacterized protein. (517 aa)
	CAEBREN_20093	Uncharacterized protein. (292 aa)
	CAEBREN_18164	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (703 aa)
	CAEBREN_08648	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (98 aa)
	CAEBREN_11293	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (98 aa)
	CAEBREN_04699	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (95 aa)
	CAEBREN_14857	CYCLIN domain-containing protein; Belongs to the cyclin family. (302 aa)
	CAEBREN_32679	Uncharacterized protein; Belongs to the cyclin family. (303 aa)
	CAEBREN_21807	TOG domain-containing protein. (2637 aa)
	CAEBREN_21021	MAT1 domain-containing protein. (122 aa)
	CAEBREN_32167	Uncharacterized protein. (220 aa)
	CAEBREN_21571	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (347 aa)
	CAEBREN_21412	Uncharacterized protein. (335 aa)
	Cbn-gcn-1	CBN-GCN-1 protein. (2639 aa)
	CAEBREN_17055	Uncharacterized protein; Belongs to the cyclin family. (303 aa)
	CAEBREN_11617	CYCLIN domain-containing protein; Belongs to the cyclin family. (302 aa)
	CAEBREN_06621	WD_REPEATS_REGION domain-containing protein. (1298 aa)
	CAEBREN_18584	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (532 aa)
	CAEBREN_06993	Cyclin N-terminal domain-containing protein. (317 aa)

Your Current Organism:

Caenorhabditis brenneri

NCBI taxonomy Id: 135651
Other names: C. brenneri, Caenorhabditis CB5161, Caenorhabditis brenneri Sudhaus & Kiontke, 2007, Caenorhabditis n. sp. CB5161, Caenorhabditis sp. 1 CB5161, Caenorhabditis sp. 4 (CB5161, LKC28, SB129, SB280), Caenorhabditis sp. 4 (CE-II), Caenorhabditis sp. CB5161, Caenorhabditis sp. PB2801

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CAEBREN_00019	CAEBREN_00250	G0MFU8	G0NG27	INCENP_ARK-bind domain-containing protein.	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	0.769
CAEBREN_00019	CAEBREN_00673	G0MFU8	G0MPM8	INCENP_ARK-bind domain-containing protein.	CYCLIN domain-containing protein; Belongs to the cyclin family.	0.635
CAEBREN_00019	CAEBREN_21571	G0MFU8	G0P285	INCENP_ARK-bind domain-containing protein.	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	0.769
CAEBREN_00019	Cbn-cyb-3	G0MFU8	G0NKP8	INCENP_ARK-bind domain-containing protein.	CBN-CYB-3 protein; Belongs to the cyclin family.	0.710
CAEBREN_00250	CAEBREN_00019	G0NG27	G0MFU8	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	INCENP_ARK-bind domain-containing protein.	0.769
CAEBREN_00250	CAEBREN_02046	G0NG27	G0NQL0	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Uncharacterized protein.	0.802
CAEBREN_00250	CAEBREN_04699	G0NG27	G0P6M3	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.	0.854
CAEBREN_00250	CAEBREN_06732	G0NG27	G0NCT6	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Uncharacterized protein.	0.523
CAEBREN_00250	CAEBREN_06993	G0NG27	G0NX87	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Cyclin N-terminal domain-containing protein.	0.498
CAEBREN_00250	CAEBREN_08072	G0NG27	G0NJQ4	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.	0.843
CAEBREN_00250	CAEBREN_08648	G0NG27	G0P6M8	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.	0.854
CAEBREN_00250	CAEBREN_09292	G0NG27	G0MJV3	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Uncharacterized protein; Belongs to the cyclin family.	0.946
CAEBREN_00250	CAEBREN_10807	G0NG27	G0PD36	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Uncharacterized protein.	0.523
CAEBREN_00250	CAEBREN_11293	G0NG27	G0P6M4	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.	0.854
CAEBREN_00250	CAEBREN_12491	G0NG27	G0NH51	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	0.813
CAEBREN_00250	CAEBREN_14236	G0NG27	G0NJB1	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	0.946
CAEBREN_00250	CAEBREN_14453	G0NG27	G0PDR6	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.	0.843
CAEBREN_00250	CAEBREN_14487	G0NG27	G0PDD2	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	0.638
CAEBREN_00250	CAEBREN_16235	G0NG27	G0MJV2	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Uncharacterized protein; Belongs to the cyclin family.	0.945
CAEBREN_00250	CAEBREN_17299	G0NG27	G0MEM9	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	UDENN FLCN/SMCR8-type domain-containing protein.	0.934

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