(139 nodes) Regulation of ion transport network (Caenorhabditis brenneri)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CAEBREN_00438	Uncharacterized protein. (368 aa)
	CAEBREN_30729	SAM domain-containing protein. (127 aa)
	CAEBREN_29181	Uncharacterized protein; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (439 aa)
	CAEBREN_30492	Uncharacterized protein. (295 aa)
	CAEBREN_32201	Uncharacterized protein; Belongs to the potassium channel family. (576 aa)
	CAEBREN_23738	Uncharacterized protein. (545 aa)
	CAEBREN_28544	Uncharacterized protein; Belongs to the potassium channel family. (474 aa)
	CAEBREN_18582	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (234 aa)
	CAEBREN_28667	PRA1 family protein. (136 aa)
	CAEBREN_31076	C2 domain-containing protein. (183 aa)
	CAEBREN_22045	Uncharacterized protein. (337 aa)
	CAEBREN_30976	Uncharacterized protein. (372 aa)
	CAEBREN_31070	Uncharacterized protein. (832 aa)
	CAEBREN_00152	Protein kinase domain-containing protein. (1773 aa)
	CAEBREN_25584	Phosphoinositide phospholipase C. (1447 aa)
	CAEBREN_18719	Uncharacterized protein; Belongs to the potassium channel family. (627 aa)
	CAEBREN_08366	Uncharacterized protein. (445 aa)
	CAEBREN_29873	Uncharacterized protein. (412 aa)
	CAEBREN_28816	Uncharacterized protein; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (737 aa)
	CAEBREN_17541	Uncharacterized protein. (239 aa)
	CAEBREN_31690	Uncharacterized protein. (439 aa)
	Cbn-cav-1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (235 aa)
	CAEBREN_29310	Uncharacterized protein. (139 aa)
	CAEBREN_06236	Uncharacterized protein. (210 aa)
	CAEBREN_19574	Uncharacterized protein. (355 aa)
	Cbn-unc-2	CBN-UNC-2 protein. (351 aa)
	CAEBREN_06143	Uncharacterized protein; Belongs to the potassium channel family. (516 aa)
	CAEBREN_02539	Uncharacterized protein. (78 aa)
	CAEBREN_20829	BTB_2 domain-containing protein. (224 aa)
	CAEBREN_20894	BTB_2 domain-containing protein. (277 aa)
	CAEBREN_31475	DAGKc domain-containing protein. (467 aa)
	Cbn-clhm-1	CBN-CLHM-1 protein. (329 aa)
	Cbn-egl-30	CBN-EGL-30 protein. (303 aa)
	CAEBREN_32581	Uncharacterized protein. (200 aa)
	CAEBREN_25368	C2 domain-containing protein. (287 aa)
	CAEBREN_09982	Uncharacterized protein. (209 aa)
	CAEBREN_11735	Uncharacterized protein. (99 aa)
	Cbn-aex-1	CBN-AEX-1 protein. (985 aa)
	CAEBREN_05251	Uncharacterized protein. (241 aa)
	Cbn-csq-1	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (417 aa)
	CAEBREN_13227	Uncharacterized protein. (156 aa)
	CAEBREN_26020	C2 domain-containing protein. (429 aa)
	CAEBREN_17069	Uncharacterized protein. (466 aa)
	CAEBREN_22038	Uncharacterized protein. (943 aa)
	CAEBREN_05564	Uncharacterized protein. (243 aa)
	Cbn-tsp-17	Tetraspanin. (243 aa)
	CAEBREN_29219	EF-hand domain-containing protein. (1344 aa)
	CAEBREN_28992	Uncharacterized protein. (812 aa)
	CAEBREN_18358	Uncharacterized protein. (122 aa)
	CAEBREN_01170	Uncharacterized protein. (116 aa)
	CAEBREN_28573	Cyclic nucleotide-binding domain-containing protein. (800 aa)
	Cbn-snt-6	CBN-SNT-6 protein. (373 aa)
	Cbn-stn-1	CBN-STN-1 protein. (388 aa)
	CAEBREN_02719	Uncharacterized protein. (1949 aa)
	CAEBREN_06933	BTB domain-containing protein; Belongs to the potassium channel family. (559 aa)
	CAEBREN_22691	Uncharacterized protein. (168 aa)
	Cbn-rab-6.2	CBN-RAB-6.2 protein. (205 aa)
	Cbn-exc-4	CBN-EXC-4 protein. (290 aa)
	CAEBREN_23731	USP domain-containing protein; Belongs to the peptidase C19 family. (434 aa)
	CAEBREN_14201	Uncharacterized protein. (121 aa)
	CAEBREN_00888	Uncharacterized protein. (890 aa)
	CAEBREN_28054	Uncharacterized protein. (112 aa)
	CAEBREN_30318	Uncharacterized protein. (78 aa)
	CAEBREN_00526	Uncharacterized protein; Belongs to the potassium channel family. (481 aa)
	CAEBREN_08677	E3 ubiquitin-protein ligase. (747 aa)
	CAEBREN_26404	Uncharacterized protein; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (438 aa)
	CAEBREN_08170	Uncharacterized protein. (158 aa)
	CAEBREN_13142	Uncharacterized protein. (355 aa)
	CAEBREN_26191	Uncharacterized protein. (233 aa)
	CAEBREN_12970	Uncharacterized protein; Belongs to the potassium channel family. (631 aa)
	CAEBREN_22555	Uncharacterized protein. (196 aa)
	CAEBREN_21624	Uncharacterized protein. (267 aa)
	CAEBREN_16938	Uncharacterized protein. (192 aa)
	Cbn-irk-1	CBN-IRK-1 protein. (544 aa)
	CAEBREN_25833	Uncharacterized protein; Belongs to the potassium channel family. (754 aa)
	CAEBREN_25902	Uncharacterized protein. (316 aa)
	Cbn-cca-1	CBN-CCA-1 protein. (2038 aa)
	Cbn-kvs-1	CBN-KVS-1 protein; Belongs to the potassium channel family. (495 aa)
	Cbn-exp-2	CBN-EXP-2 protein; Belongs to the potassium channel family. (513 aa)
	Cbn-stim-1	CBN-STIM-1 protein. (525 aa)
	CAEBREN_18531	Uncharacterized protein. (286 aa)
	CAEBREN_05779	Galectin. (145 aa)
	CAEBREN_31448	Uncharacterized protein. (366 aa)
	CAEBREN_18745	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (699 aa)
	Cbn-mps-1	CBN-MPS-1 protein. (262 aa)
	CAEBREN_29643	Uncharacterized protein. (241 aa)
	Cbn-slo-1	CBN-SLO-1 protein. (1124 aa)
	Cbn-sphk-1	CBN-SPHK-1 protein. (413 aa)
	CAEBREN_29912	Uncharacterized protein. (31 aa)
	CAEBREN_08298	Uncharacterized protein; Belongs to the potassium channel family. (1345 aa)
	CAEBREN_11995	Uncharacterized protein. (424 aa)
	Cbn-irk-3	CBN-IRK-3 protein. (374 aa)
	Cbn-unc-36	CBN-UNC-36 protein. (1233 aa)
	CAEBREN_30062	Uncharacterized protein. (709 aa)
	CAEBREN_00627	Uncharacterized protein. (239 aa)
	CAEBREN_30173	Uncharacterized protein. (36 aa)
	CAEBREN_29859	Ion_trans domain-containing protein; Belongs to the potassium channel family. (146 aa)
	CAEBREN_05772	Ion_trans_2 domain-containing protein. (69 aa)
	CAEBREN_00367	UDENN domain-containing protein. (1447 aa)
	CAEBREN_09179	Uncharacterized protein. (832 aa)
	CAEBREN_30859	Uncharacterized protein. (75 aa)
	CAEBREN_02056	Uncharacterized protein; Belongs to the potassium channel family. (548 aa)
	CAEBREN_04845	Uncharacterized protein. (195 aa)
	Cbn-egl-3	CBN-EGL-3 protein; Belongs to the peptidase S8 family. (652 aa)
	Cbn-shw-3	CBN-SHW-3 protein. (242 aa)
	CAEBREN_21315	Uncharacterized protein. (145 aa)
	CAEBREN_08970	Uncharacterized protein; Belongs to the potassium channel family. (528 aa)
	Cbn-stg-1	CBN-STG-1 protein. (368 aa)
	Cbn-pde-2	Phosphodiesterase. (805 aa)
	Cbn-egl-8	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1255 aa)
	CAEBREN_12552	Uncharacterized protein. (1003 aa)
	CAEBREN_08195	C2 domain-containing protein. (183 aa)
	CAEBREN_13701	Uncharacterized protein. (374 aa)
	CAEBREN_15502	Uncharacterized protein. (287 aa)
	Cbn-ccb-1	CBN-CCB-1 protein. (523 aa)
	CAEBREN_15422	GuKc domain-containing protein. (523 aa)
	CAEBREN_31807	Uncharacterized protein; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (122 aa)
	Cbn-asic-1	CBN-ASIC-1 protein; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (709 aa)
	CAEBREN_02058	Uncharacterized protein. (1660 aa)
	Cbn-gar-3	CBN-GAR-3 protein. (364 aa)
	CAEBREN_17835	G_PROTEIN_RECEP_F1_2 domain-containing protein. (119 aa)
	CAEBREN_07224	C2 domain-containing protein. (482 aa)
	Cbn-dop-2	CBN-DOP-2 protein; Belongs to the G-protein coupled receptor 1 family. (904 aa)
	Cbn-wnk-1	CBN-WNK-1 protein. (1966 aa)
	CAEBREN_32094	Uncharacterized protein. (442 aa)
	CAEBREN_09828	Uncharacterized protein. (1231 aa)
	CAEBREN_20723	Uncharacterized protein. (2340 aa)
	Cbn-egl-21	CBN-EGL-21 protein. (483 aa)
	CAEBREN_29473	Uncharacterized protein. (66 aa)
	CAEBREN_07774	Uncharacterized protein; Belongs to the potassium channel family. (451 aa)
	CAEBREN_23943	Uncharacterized protein. (309 aa)
	CAEBREN_31959	Uncharacterized protein. (537 aa)
	Cbn-mps-3	CBN-MPS-3 protein. (166 aa)
	CAEBREN_14963	CUB domain-containing protein. (227 aa)
	CAEBREN_11957	BTB domain-containing protein; Belongs to the potassium channel family. (581 aa)
	Cbn-mef-2	CBN-MEF-2 protein. (345 aa)
	CAEBREN_30535	Uncharacterized protein. (429 aa)
	Cbn-snt-4	CBN-SNT-4 protein. (382 aa)
	CAEBREN_14045	SH3 domain-containing protein. (366 aa)

Your Current Organism:

Caenorhabditis brenneri

NCBI taxonomy Id: 135651
Other names: C. brenneri, Caenorhabditis CB5161, Caenorhabditis brenneri Sudhaus & Kiontke, 2007, Caenorhabditis n. sp. CB5161, Caenorhabditis sp. 1 CB5161, Caenorhabditis sp. 4 (CB5161, LKC28, SB129, SB280), Caenorhabditis sp. 4 (CE-II), Caenorhabditis sp. CB5161, Caenorhabditis sp. PB2801

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CAEBREN_00152	Cbn-egl-3	G0PG55	G0N929	Protein kinase domain-containing protein.	CBN-EGL-3 protein; Belongs to the peptidase S8 family.	0.507
CAEBREN_00367	CAEBREN_12552	G0N7K3	G0NCX0	UDENN domain-containing protein.	Uncharacterized protein.	0.566
CAEBREN_00367	Cbn-aex-1	G0N7K3	G0P115	UDENN domain-containing protein.	CBN-AEX-1 protein.	0.566
CAEBREN_00367	Cbn-dop-2	G0N7K3	G0NPR6	UDENN domain-containing protein.	CBN-DOP-2 protein; Belongs to the G-protein coupled receptor 1 family.	0.572
CAEBREN_00438	CAEBREN_02058	G0MIW1	G0NJQ0	Uncharacterized protein.	Uncharacterized protein.	0.597
CAEBREN_00438	CAEBREN_16938	G0MIW1	G0MR45	Uncharacterized protein.	Uncharacterized protein.	0.667
CAEBREN_00438	CAEBREN_18582	G0MIW1	G0PJQ0	Uncharacterized protein.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.550
CAEBREN_00438	CAEBREN_21624	G0MIW1	G0MR40	Uncharacterized protein.	Uncharacterized protein.	0.667
CAEBREN_00438	CAEBREN_22555	G0MIW1	G0MR36	Uncharacterized protein.	Uncharacterized protein.	0.667
CAEBREN_00438	CAEBREN_23738	G0MIW1	G0PLF0	Uncharacterized protein.	Uncharacterized protein.	0.597
CAEBREN_00438	CAEBREN_30729	G0MIW1	G0PMW1	Uncharacterized protein.	SAM domain-containing protein.	0.953
CAEBREN_00438	Cbn-cav-1	G0MIW1	G0PBA9	Uncharacterized protein.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.550
CAEBREN_00438	Cbn-egl-21	G0MIW1	G0NS04	Uncharacterized protein.	CBN-EGL-21 protein.	0.468
CAEBREN_00438	Cbn-egl-30	G0MIW1	G0P5J3	Uncharacterized protein.	CBN-EGL-30 protein.	0.660
CAEBREN_00438	Cbn-mef-2	G0MIW1	G0NXP2	Uncharacterized protein.	CBN-MEF-2 protein.	0.527
CAEBREN_00438	Cbn-pde-2	G0MIW1	G0NB39	Uncharacterized protein.	Phosphodiesterase.	0.411
CAEBREN_00438	Cbn-rab-6.2	G0MIW1	G0MIG9	Uncharacterized protein.	CBN-RAB-6.2 protein.	0.602
CAEBREN_00526	CAEBREN_02056	G0ML84	G0N8Q8	Uncharacterized protein; Belongs to the potassium channel family.	Uncharacterized protein; Belongs to the potassium channel family.	0.416
CAEBREN_00526	CAEBREN_04845	G0ML84	G0N925	Uncharacterized protein; Belongs to the potassium channel family.	Uncharacterized protein.	0.459
CAEBREN_00526	CAEBREN_06933	G0ML84	G0MI63	Uncharacterized protein; Belongs to the potassium channel family.	BTB domain-containing protein; Belongs to the potassium channel family.	0.515

page 1 of 62

Server load: low (16%) [HD]

Permalink

Network

Neighborhood

Experiments

Fusion

Databases

Cooccurrence

Textmining

Coexpression

© STRING Consortium 2025

Credits

Access

Info

About